Search results for "ship"
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Appetite for destruction: A psychometric examination and prevalence estimation of destructive leadership in Sweden
2021
There is a growing awareness that destructive leadership has a significant negative impact on employe outcomes. However, little is known about the content and dimensionality of this multidimensional concept, and there are few reliable measures available for organizations and researchers to evaluate these behaviors. Based on a representative sample (N = 1132) of the Swedish workforce, the aim of this study is threefold: first, to examine the factor structure and validity of an easy-to-use multidimensional destructive leadership measure (Destrudo-L)in the general Swedish work context; second, to identify destructive leadership profiles using latent profile analysis (LPA), and determine in wha…
From Graz to Göttingen: Neugebauer’s Early Intellectual Journey
2016
Otto Neugebauer’s early academic career was marked by a series of transitions. His interests shifted from physics to mathematics, and finally to the history of ancient mathematics and exact sciences. Yet even from his early years in Graz, Neugebauer was strongly attracted to the mathematical culture of Gottingen. When he arrived there in 1922, he quickly established a strong personal friendship with Richard Courant, the newly appointed Director of the Mathematics Institute. Neugebauer and Courant worked together closely up until 1933, when the Nazi government decimated the Gottingen scientific community. In this essay, Neugebauer’s historical work and his vision for a new approach to the st…
Students’ Perceptions of Family Entrepreneurship – A Study on Family Business Academic Education
2010
L’objectif de cette recherche est d’analyser les points de vue d’étudiants universitaires envers la condition des entrepreneurs. Le fond théorique analyse l’interaction entre l’entreprise familiale, le propriétaireship, et l’éducation sur la condition des entrepreneurs. 211 étudiants de l’Université de Jyväskylä ont participé à cette étude pendant le cours fondamental de Basic business studies appelé “Introduction to Entrepreneurship and Business Operations” en septembre 2007. 143 d’entre eux ont écrit un essai d’une page, soit en finnois soit en anglais, sur les entreprises familiales et les propriétaires familiales. Les étudiants ont écrit sur le phénomène avec leurs propres mots. Les rés…
Promoting children’s participation: the role of teachers in preschool and primary school learning sessions
2010
The aim of this study is to provide insights into the social construction of participation in joint activities in Finnish preschool and primary school classrooms. The article deals with two issues: How do teachers promote participation in a preschool classroom as compared with a primary school classroom? What similarities and differences are found? It also considers the question of how the similarities contribute to the continuity from preschool to primary school in terms of participation. Based on observation data insights are provided into the interactions between teachers and children by using extracts from teacher‐led learning sessions. The teachers used a diversity of strategies to pro…
Dual targeting of higher-order DNA structures by azacryptands induces DNA junction-mediated DNA damage in cancer cells
2021
Abstract DNA is intrinsically dynamic and folds transiently into alternative higher-order structures such as G-quadruplexes (G4s) and three-way DNA junctions (TWJs). G4s and TWJs can be stabilised by small molecules (ligands) that have high chemotherapeutic potential, either as standalone DNA damaging agents or combined in synthetic lethality strategies. While previous approaches have claimed to use ligands that specifically target either G4s or TWJs, we report here on a new approach in which ligands targeting both TWJs and G4s in vitro demonstrate cellular effects distinct from that of G4 ligands, and attributable to TWJ targeting. The DNA binding modes of these new, dual TWJ-/G4-ligands w…
Andrei Șerban: The Search for ‘New Forms’
2021
This chapter discusses the theatre of Andrei Șerban, definitely one of the most important theatre directors of the second half of the twentieth century. He began directing in Communist Romania in the 1960s and had to deal with censorship, so in order to avoid this uncomfortable context, he focused on interpreting the text—he constantly searched for new nuances and made use of all possible subtexts. These are the premises of his work and when he moved to the USA, he continued this artistic strategy. Throughout his career, Andrei Șerban has been passionate about staging The Seagull (five times), as he is constantly looking for new forms, just like Chekhov’s character Treplev. A special accent…
Using Crowdsourcing to Overcome Barriers to Women Entrepreneurship
2015
This chapter presents crowdsourcing as a novel way of overcoming barriers facing women entrepreneurs, offering alternatives to conventional solutions. The study analyzes three barriers to women entrepreneurship: access to financing, access to specific management knowledge, and access to information and communication technologies (ICTs). For each barrier, a different form of crowdsourcing is proposed: crowdfunding, crowd wisdom, and crowdfunded media, respectively. Using these crowdsourcing tools, women entrepreneurs can overcome major difficulties when starting businesses.
The self-perceived commitment and relationship maintenance behaviors among Finnish-Chinese couples in Finland : an application of the investment mode…
2015
The investment model (2003) has been widely used in romantic relationship studies but rarely in an intercultural context. This study tests the investment model by examining Finnish-Chinese couples’ self-perceptions of commitment level and relationship maintenance behaviors. A qualitative research method with deductive thematic analysis approach is applied. This study finds that Finnish-Chinese couples have relatively high level of commitment. They tend to remain in their relationships, to actively derogate alternatives, to sacrifice self-welfare for gratifying relationship well-being, to perceive their relationships as good and healthy and to choose relationship constructive responses under…
Detection of an O-methyltransferase synthesising acetosyringone in methyl jasmonate-treated tobacco cell-suspensions cultures.
2013
Acetosyringone (3',5'-dimethoxy-4'-hydroxyacetophenone) is a well-known and very effective inducer of the virulence genes of Agrobacterium tumefaciens but the precise pathway of its biosynthesis in plants is still unknown. We have used two tobacco cell lines, cultured in suspension and exhibiting different patterns of accumulation of acetosyringone in their culture medium upon treatment with methyl jasmonate, to study different steps of acetosyringone biosynthesis. In the two cell lines studied, treatment with 100 mu M methyl jasmonate triggered a rapid and transient increase in acetovanillone synthase activity followed by a progressive increase in S-adenosyl-L-methionine: 5-hydroxyacetovan…
Cladosins L-O, new hybrid polyketides from the endophytic fungus Cladosporium sphaerospermum WBS017
2019
Abstract The endophytic fungus Cladosporium sphaerospermum WBS017 was obtained from healthy bulbs of Fritillaria unibracteata var. wabuensis. Fermentation of C. sphaerospermum on solid rice medium yielded three new hybrid polyketides, cladosins L−N (1–3), and a known derivative cladodionen (4). Further cultivation of this fungus on white bean medium afforded an additional new hybrid polyketide, cladosin O (5) along with three known analogues (6–8). The structures of the new compounds were elucidated using a combination of NMR and HRESIMS data. The absolute configurations of compounds 2 and 3 were determined by Mosher’s method and TDDFT-ECD calculations. All isolated compounds were evaluated…