Search results for "sida"
showing 10 items of 1584 documents
Evolutionary History and Functional Characterization of the Amphibian Xenosensor CAR
2011
AbstractThe xenosensing constitutive androstane receptor (CAR) is widely considered to have arisen in early mammals via duplication of the pregnane X receptor (PXR). We report that CAR emerged together with PXR and the vitamin D receptor from an ancestral NR1I gene already in early vertebrates, as a result of whole-genome duplications. CAR genes were subsequently lost from the fish lineage, but they are conserved in all taxa of land vertebrates. This contrasts with PXR, which is found in most fish species, whereas it is lost from Sauropsida (reptiles and birds) and plays a role unrelated to xenosensing in Xenopus. This role is fulfilled in Xenopus by CAR, which exhibits low basal activity a…
Solapamiento del nicho trófico en un área de cría en la costa portuguesa
2002
The diets and the trophic niche overlap between seven flatfish species were studied in a coastal nursery adjoining to the Tagus estuary (Portugal). Fish were sampled monthly, from March to November 1999, using a beach seine. Arnoglossus imperialis (Rafinesque, 1810), Arnoglossus laterna (Walbaum, 1792) and Arnoglossus thori Kyle, 1913, fed mainly on crustaceans. The diets of Buglossidium luteum (Risso, 1810) and Dicologoglossa cuneata (Moreau, 1881) were mainly composed of Bivalvia and Polychaeta, while for Scophthalmus rhombus (Linnaeus, 1758) the main food items were Mysidacea and Teleostei. The diet of Pegusa lascaris (Risso, 1810) was mainly composed by Cumacea, Bivalvia, Decapoda and A…
Changes in Terpene Content in Milk from Pasture-Fed Cows
2006
Changes of terpene content in milk from cows grazing natural diversified upland pasture were examined in this observational trial. A homogeneous plot divided into 2 subplots was used from May 31 to July 1, 2003 (first growth) and again from October 1 to October 7, 2003 (vegetative regrowth). Each subplot was grazed by 6 dairy cows in 2 ways: strip grazing (SG), with new allocations of pasture strips at 2-d intervals, and paddock grazing (PG). The PG subplot was divided into 3 paddocks and the cows were moved to a new paddock on June 13 and June 24, 2003. Milk from the 6 cows was collected twice a week, pooled, and used for terpene analyses by dynamic headspace gas chromatography-mass spectr…
La transversalidad de los trastornos del comportamiento alimentario: un reto para los cuidados de salud
2004
Los trastornos de la conducta alimentaria son una causa importante de morbilidad física y psicosocial en jóvenes adolescentes y en mujeres adultas jóvenes y, aunque en distinto grado, afectan a personas tanto de países desarrollados como de países en vías de desarrollo. En este trabajo se expone como ejemplo la situación España y Perú. Se trata de un problema de origen multicausal que es transversal a condiciones socioeconómicas y clase social y en la actualidad, es la teoría del factor sociocultural la que mejor soporta la interpretación de los datos disponibles. En este contexto, el rol y la responsabilidad que compete a Enfermería y a otros profesionales de la salud tiene grandes dimensi…
Influencia de las variables sociodemográficas sobre la ansiedad y el rendimiento académico adolescente: el contexto pluricultural de Ceuta
2019
Este trabajo tiene como objetivo fundamental analizar la ansiedad y el rendimiento académico, sus tipos y niveles en función de edad, género, cultura y estrato socioeconómico, así como contemplar las relaciones entre ambas. Se contó con 811 participantes. El 71.6% de la muestra eran musulmanes, mientras que el 28.4% eran cristianos; el 46.1% hombres y el 53.9% mujeres. Como instrumentos de evaluación se empleó el STAIC (Spielberger, 2001) y las calificaciones del alumnado. Se reflejan niveles medio-bajos en ansiedad y medios en rendimiento académico. En la ansiedad influyen edad, género, cultura/religión y estatus socio-económico-cultural. Sobre el rendimiento actúan la edad, la cultura y e…
El enfermo de Sida y otros enfermos crónicos : estudio de la interacción en contextos hospitalarios y de la vivencia de la enfermedad
2016
Este estudio se centra en el enfermo crónico hospitalizado de larga estancia, concretamente enfermos de sida (fase terminal) y otros enfermos crónicos (estado grave). El objetivo fue analizar las diferencias entre ambos grupos de enfermos en las variables relacionadas con la vivencia de la enfermedad, y en las interacciones entre estos enfermos y el resto de las personas que interactúan con ellos en el contexto hospitalario. Los participantes fueron 51 enfermos crónicos hospitalizados en un hospital de larga estancia de la provincia de Valencia, 20 de sida y 31 de otras patologías. El 64.7% fueron hombres y el 35.3% mujeres, con una edad promedio de 55.02 años (DT = 18.8). Los instrumentos …
A role for the MAP kinase gene MKC1 in cell wall construction and morphological transitions in Candida albicans.
1998
The Candida albicans MKC1 gene encodes a mitogen-activated protein (MAP) kinase, which has been cloned by complementation of the lytic phenotype associated with Saccharomyces cerevisiae slt2 (mpk1) mutants. In this work, the physiological role of this MAP kinase in the pathogenic fungus C. albicans was characterized and a role for MKC1 in the biogenesis of the cell wall suggested based on the following criteria. First, C. albicans mkc1Δ/mkc1Δ strains displayed alterations in their cell surfaces under specific conditions as evidenced by scanning electron microscopy. Second, an increase in specific cell wall epitopes (O-glycosylated mannoprotein) was shown by confocal microscopy in mkc1Δ/mkc1…
Secretion, interaction and assembly of two O-glycosylated cell wall antigens from Candida albicans.
2001
The mechanisms of incorporation of two antigens have been determined using a monoclonal antibody (3A10) raised against the material released from the mycelial cell wall by zymolyase digestion and retained on a concanavalin A column. One of the hybridomas secreted an IgG that reacted with two bands in Western blots. Indirect immunofluorescence showed that the antigens were located on the surfaces of mycelial cells, but within the cell walls of yeasts. These antigens were detected in a membrane preparation, in the SDS-soluble material and in the material released by a 1,3-beta-glucanase and chitinase from the cell walls of yeast and mycelial cells. In the latter three samples, an additional h…
Characterization of cell wall proteins from yeast and mycelial cells of Candida albicans by labelling with biotin: Comparison with other techniques
1992
Candida albicans ATCC 26555 blastoconidia and blastoconidia bearing germ tubes were metabolically labelled by incubating the cells with 14C-labelled protein hydrolysate and were subsequently tagged with biotin. Double-labelled (radioactive and biotinylated) cell wall proteins and glycoproteins were extracted from intact cells of both growth forms by treatment with 2-mercaptoethanol (beta ME) and with beta-glucanases (Zymolyase) after treatment with beta ME. The beta ME- and Zymolyase-extracts were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and western blotted (immunoblotted) to nitrocellulose paper. Polyacrylamide gels were stained with Coomassie blue and process…
Šķidruma hromatogrāfijas un masspektrometrijas metožu izstrāde un pielietojums antioksidantu noteikšanai
2017
Antioksidanti ir plaši izplatīti augu valsts pārtikas produktos un pēdējā desmitgadē tiem ir pievērsta pastiprināta uzmanība. Pateicoties to veselību uzlabojošajām īpašībām, ir radusies palielināta interese par to noteikšanas veidiem dažāda veida augos un augu izcelsmes produktos. Līdz ar augsti efektīvās šķidrumu hromatogrāfijas pieejamību apvienojumā ar augstas izšķirtspējas masspektrometriju, ir pavērti jauni apvāršņi analītisko metožu izstrādei sarežģītās paraugu matricās. Darbā dots ieskats par antioksidantu un polifenolu īpašībām, to izdalīšanu no pārtikas produktiem, paraugu sagatavošanas un noteikšanas metodēm, izmantojot augsti efektīvās šķidruma hromatogrāfijas metodes. Kā pētījum…