Search results for "simplex"

showing 10 items of 159 documents

Endoparasites of the blue whiting, Micromesistius poutassou from north-west Spain.

2005

AbstractThe communities of metazoan endoparasites of blue whiting, Micromesistius poutassou, in waters of north-west Spain were analysed and a geographical comparison made with other localities. Four hundred blue whiting collected in July 1999 and September 2000 were examined for parasites, excluding the head and gills. Six species were found: Anisakis simplex s.l. (L3), A. physeteris (L3), Hysterothylacium aduncum (L2 and L3), Stephanostomum lophii (metacercaria), S. pristis (adult), and Prosorhynchus crucibulum (metacercaria). The latter is a new host record, and A. physeteris is reported for the first time in blue whiting from the north-east Atlantic. Host gender was not a significant pr…

GillFood ChainbiologyNematodaEcologyFaunaAnisakis simplexFishesMicromesistiusGeneral Medicinebiology.organism_classificationBlue whitingAnisakiasisHost-Parasite InteractionsFish DiseasesSpainHelminthsDominance (ecology)AnimalsAnimal Science and ZoologyParasitologySeawaterSpecies richnessNematode InfectionsEcosystemJournal of helminthology
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Involvement of actin-containing microfilaments in HSV-induced cytopathology and the influence of inhibitors of glycosylation.

1986

Two and a half hours after infection with a high dose of different strains of HSV-1 which induce rounding of cells, breakdown of actin containing microfilaments can be observed. At the periphery of the cell, actin containing knob-like protuberances were visible. Later on, actin seems to be located exclusively on the surface of cells. Observations were done by immunofluorescence microscopy, scanning electron-microscopy and immunoperoxidase staining of ultrathin sections. The envelope of HSV appears to be stained by anti-actin. Strain IES produces rounding of cells at a high dose of infection before fusion proceeds at 37 degrees C. Similar alterations were not observed with the fusing strains…

GlycosylationGlycosylationCellBiologyDeoxyglucoseMicrofilamentVirusCell LineCell Fusionchemistry.chemical_compoundCytopathogenic Effect ViralFluorodeoxyglucose F18VirologymedicineAnimalsSimplexvirusActinCells CulturedCytoskeletonchemistry.chemical_classificationTunicamycinCell MembraneGeneral MedicineTunicamycinVirologyActinsActin CytoskeletonMicroscopy Electronmedicine.anatomical_structurechemistryCytopathologyGlycoproteinArchives of virology
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Successful treatment of HSV encephalitis during pregnancy.

1989

A propos d'une femme presentant une grossesse de 23 semaines. Description des signes cliniques et electroencephalographiques. Les effets de l'aciclovir sur l'encephalite et sur l'evolution de la grossesse sont etudies

GynecologyAdultPregnancymedicine.medical_specialtyChemotherapybusiness.industrymedicine.medical_treatmentAcyclovirHerpes Simplexmedicine.diseasePregnancyImmunologymedicineGestationEncephalitisHumansFemaleNeurology (clinical)AciclovirHsv encephalitisPregnancy Complications InfectiousbusinessEncephalitismedicine.drugNeurology
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Consensus guidelines for the detection of immunogenic cell death

2014

Apoptotic cells have long been considered as intrinsically tolerogenic or unable to elicit immune responses specific for dead cell-associated antigens. However, multiple stimuli can trigger a functionally peculiar type of apoptotic demise that does not go unnoticed by the adaptive arm of the immune system, which we named "immunogenic cell death" (ICD). ICD is preceded or accompanied by the emission of a series of immunostimulatory damage-associated molecular patterns (DAMPs) in a precise spatiotemporal configuration. Several anticancer agents that have been successfully employed in the clinic for decades, including various chemotherapeutics and radiotherapy, can elicit ICD. Moreover, defect…

HSV-1 herpes simplex virus type IΔψm mitochondrial transmembrane potentialmedicine.medical_treatmentDAMP damage-associated molecular patterndetectionFLT3LG fms-related tyrosine kinase 3 ligandReviewmember 3calreticulinEukaryotic translation initiation factor 2ARFP red fluorescent protein0302 clinical medicineMOMP mitochondrial outer membrane permeabilizationImmunology and AllergyGFP green fluorescent proteinHMGB10303 health scienceseducation.field_of_studyToll-like receptorBAK1 BCL2-antagonist/killer 1H2B histone 2Bendoplasmic reticulum stre3. Good healthBAX BCL2-associated X proteinXBP1 X-box binding protein 1cell deathOncologyPDIA3 protein disulfide isomerase family A030220 oncology & carcinogenesisendoplasmic reticulum stressImmunogenic cell deathHSP heat shock proteinimmunotherapyTLR Toll-like receptorautophagyATF6 activating transcription factor 6ImmunologyICD immunogenic cell deathEIF2A eukaryotic translation initiation factor 2AGuidelinesBiologyBCL2 B-cell CLL/lymphoma 2 proteinER endoplasmic reticulumPI propidium iodideATP release03 medical and health sciencesImmune systemimmunogenicmedicineIFN interferonAntigen-presenting celleducation030304 developmental biologyCALR calreticulinDamage-associated molecular patternImmunotherapyCTL cytotoxic T lymphocyteHMGB1 high mobility group box 1IL interleukinG3BP1 GTPase activating protein (SH3 domain) binding protein 1APC antigen-presenting cellCancer cellImmunologyDiOC6(3) 33′-dihexyloxacarbocyanine iodideDAPI 4′6-diamidino-2-phenylindoleOncoImmunology
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Hepatitis Due to Non-A-E Viruses

2011

HepatitisTorque teno virusViral culturebusiness.industryYellow feverCongenital cytomegalovirus infectionmedicine.disease_causemedicine.diseaseEpstein–Barr virusVirologyHerpes simplex virusmedicinebusinessAcute hepatitis
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Recurrent intraoral HSV-1 infection : a retrospective study of 58 immunocompetent patients from Eastern Europe

2010

Objectives. To revise the clinical features of the recurrent intraoral herpetic infection (RIOH) with respect to precipitating factors, demographic, clinical features and outcome. Study design. Fifty-eight, unrelated Caucasian, immunocompetent patients with positive laboratory test for intraoral Herpes simplex virus infection were studied. Results. The mean age in the women?s group (n=42) was 41.23 years (± 21.73) and in the men?s group was 32.25 years (± 15.68). Possible trigger factors were identified in 9 cases (15.5%). General symptoms were noted in 20 cases (34.48%). Most of patients in this study presented multiple lesions. 14 patients had vermillion lesions associated with intraoral …

Herpes simplex virus infectionAdultMalemedicine.medical_specialtyAdolescentHSL and HSVHerpesvirus 1 HumanYoung AdultRecurrenceMedicineHumansYoung adultChildGeneral DentistryAgedRetrospective StudiesAged 80 and overbusiness.industryGeneral symptomsRomaniaMean ageRetrospective cohort studyHerpes SimplexMiddle Aged:CIENCIAS MÉDICAS [UNESCO]DermatologySurgeryLaboratory testOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryFemaleImmunocompetencebusinessImmunocompetence
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LEVELS OF RIBONUCLEASE H IN CELLS INFECTED WITH HERPES SIMPLEX VIRUS TYPE1

1981

Herpes simplex virusbiologyChemistrymedicinebiology.proteinmedicine.disease_causeRNase HVirology
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Estudio longitudinal del impacto de la violencia de pareja sobre la salud física y el sistema inmune de las mujeres

2009

Introducción: Diversos estudios transversales han demostrado el impacto negativo quela violencia de pareja tiene en la salud mental, en la salud física y en el funcionamientode los sistemas fisiológicos de las mujeres. Si bien, han sido pocos los estudioslongitudinales realizados para establecer la evolución de dicho impacto en la salud delas mujeres a lo largo del tiempo. Objetivos: En este estudio se pretendió, en primerlugar, determinar la evolución del estado de salud física y del funcionamiento delsistema inmune de las mujeres víctimas de violencia de pareja y, en segundo lugar,establecer los factores personales y sociales que contribuyen a la recuperación de lasalud o la perjudican. M…

Herpes simplexsalud físicaFacultat de Psicologiaestrés. / Intimate partner violence316159.9Herpes simplemujeresPsicologiaSociologia. Comunicacióstress.womenviolencia de parejaphysical health
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Localization of latency-associated transcripts in the uterovaginal plexus of herpes simplex virus type 1 and 2 latently infected mice.

1997

The vagina and medulla of the adrenal gland of mice vaginally infected with herpes simplex virus (HSV) types 1 and 2 were examined in the latent stage of infection (5 to 51 weeks post-infection). RNA in situ hybridization with HSV-1 and -2 latency-associated transcript (LAT) RNA probes resulted in positively stained neuronal cell nuclei in the uterovaginal plexus, but not in the medulla of the adrenal gland. These organs were chosen because HSV antigens can be detected not only in the vaginal epithelium, but also in neurons of the uterovaginal plexus and in the medulla of the adrenal gland at the acute stage of genital infection. To our knowledge, this is the first report describing LATs in…

Herpesvirus 2 HumanvirusesCellHerpesvirus 1 HumanIn situ hybridizationBiologyVulvitismedicine.disease_causemedicine.nerveMiceAntigenUterovaginal plexusVirologymedicineAnimalsHumansRNA MessengerVaginitisMedullaNeuronsMice Inbred BALB CHerpes GenitalisAdrenal glandUterusHerpes SimplexVirologyVirus LatencyDisease Models Animalmedicine.anatomical_structureHerpes simplex virusDNA ViralVaginaVaginaFemaleJournal of General Virology
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Apoptosis induced by (E)-5-(2-bromovinyl)-2'-deoxyuridine in varicella zoster virus thymidine kinase-expressing cells is driven by activation of c-Ju…

2003

The molecular mode of cell killing by the antiviral drug (E)-5-(2-bromovinyl-2'-deoxyuridine (BVDU) was studied in Chinese hamster ovary (CHO) cells stably transfected with the thymidine kinase gene (tk) of varicella zoster virus (CHO-VZVtk). The colony-forming ability of the cells was reduced to <1% at a concentration of approximately 1 microM BVDU, whereas for nontransfected cells or cells transfected with tk gene of herpes simplex virus type 1 (CHO-HSVtk), a 1000-fold higher dose was required to achieve the same response. BVDU inhibited thymidylate synthase in CHO-VZVtk but not in CHO-HSVtk and control cells. On the other hand, the drug was incorporated into DNA of VZVtk- and HSVtk-expre…

Herpesvirus 3 HumanFas Ligand ProteinFas-Associated Death Domain ProteinApoptosisCHO CellsBiologyTransfectionAntiviral AgentsThymidine KinaseFas ligandchemistry.chemical_compoundNecrosisCricetinaeCytotoxic T cellAnimalsSimplexvirusAdaptor Proteins Signal TransducingPharmacologyCaspase 8GenomeMembrane GlycoproteinsChinese hamster ovary cellCell CycleJNK Mitogen-Activated Protein KinasesTransfectionDNAThymidylate SynthaseMolecular biologyCaspase 9Transcription Factor AP-1Cell killingchemistryBromodeoxyuridineApoptosisThymidine kinaseCaspasesMolecular MedicineMitogen-Activated Protein KinasesCarrier ProteinsBromodeoxyuridineMolecular pharmacology
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