Search results for "site"

Ecological impacts of invasive signal crayfish in large boreal lakes

2012

Data and code for manuscript: Increasing human environmental footprint does not lead to biotic homogenization of forest bird communities in northern …

2023

R-code and data for replicating statistical analyses used in the study: Increasing human environmental footprint does not lead to biotic homogenization of forest bird communities in northern USA. This study examined how forest loss and increased human domination in the state of Minnesota in the USA were associated with diversity of forest birds using bird count data.

Studies of transition-edge sensor physics : thermal models and noise

2011

This thesis focuses on studying the noise in transition-edge sensors (TES). More specifically, the aim is to find an explanation for the observed excess noise that is limiting their performance and has been troubling the TES field in recent years. Several theories have been put forth but a definitive answer is still missing. In the early stages of this thesis work a novel theory was presented for the noise in a special TES geometry. In our theory the excess noise is caused by correlated fluctuations of superconductivity at the phase boundary between normal and superconducting states. Data from more recent experiments does not give solid support for the theory and in this thesis the validity…

Comprehensive analysis of interacting proteins and genome-wide location studies of the Sas3-dependent NuA3 histone acetyltransferase complex

2014

Highlights • We characterise Sas3p and Gcn5p active HAT complexes in WT and deleted TAP-strains. • We confirm that Pdp3p interacts with NuA3, histones and chromatin regulators. • Pdp3p MS-analysis reveals its phosphorylation, ubiquitination and methylation. • Sas3p can substitute Gcn5p in acetylation of histone H3K14 but not of H3K9. • Genome-wide profiling of Sas3p supports its involvement in transcriptional elongation.

A review of the analytical and numerical modeling of composites

2016

This review article is dedicated to the materials that are made from two or more constituent materials with different physical and/or chemical properties. The focus is on the materials, where the individual components remain separate and distinct within the final structure. The new combined material usually have some additional characteristic properties compared to the individual components, or, in other case, some critical properties of combined material may follow almost equally one of the components. Typically, preferred properties of the new material can be such as strength, porosity, conductivity or cheapness. The ultimate goal of this study is to find methods and tools for achieve adequ…

Relationship between cladoceran (Crustacea) functional diversity and lake trophic gradients

2017

Functional diversity (FD) as a biodiversity measure has an explicit role in ecosystem functioning because the effects of environmental changes in ecosystems are determined by biological functions, such as feeding type and trophic position, of particular species. We evaluated the usability of functional characterization and FD of an aquatic keystone group (Crustacea: Cladocera) for enhancing the understanding of long-term lake functional responses to environmental changes. The aims were to separate ecologically significant functional groups, investigate succession of such functional groups during nutrient enrichment process and determine the relationship between FD and lake productivity usin…

De l’ingénierie de protéines de liaison aux odorants à la détection électrochimique de molécules volatiles vers la conception de biocapteurs et nez é…

2014

The detection of odorant molecules has become an important challenge in different research area, such as the food industry, medical diagnostics and homeland security. Indeed, the thousands of odorants in our environment provide information on their chemical nature or their concentration. Human olfactory system is capable of discriminating thousands of different molecules thanks to biochemical mechanisms involving multiple protein receptor partners and a combinatorial coding. These biomolecules that include olfactory receptors and odorant-binding proteins (OBP) represent an interesting source of detectors for the design of biosensors. OBPs are small soluble proteins present in nasal mucus at…

The role of SAXS and molecular simulations in 3D structure elucidation of a DNA aptamer against lung cancer

2021

Aptamers are short, single-stranded DNA or RNA oligonucleotide molecules that function as synthetic analogs of antibodies and bind to a target molecule with high specificity. Aptamer affinity entirely depends on its tertiary structure and charge distribution. Therefore, length and structure optimization are essential for increasing aptamer specificity and affinity. Here, we present a general optimization procedure for finding the most populated atomistic structures of DNA aptamers. Based on the existed aptamer LC-18 for lung adenocarcinoma, a new truncated LC-18 (LC-18t) aptamer LC-18t was developed. A three-dimensional (3D) shape of LC-18t was reported based on small-angle X-ray scattering…

On displacement-velocity coupling and the origin of in-plane stress in orthotropic moving continua

2014

In this paper, we address the problem of the origin of in-plane stresses in continuous, two-dimensional high-speed webs. In the case of thin, slender webs, a typical modeling approach is the application of a stationary in-plane model, without considering the effects of in-plane velocity field. However, for high-speed webs this approach is insufficient, because it neglects the coupling between the total material velocity and the deformation experienced by the material. By using a mixed Lagrange–Euler approach in model derivation, the solid continuum problem can be transformed to solid a continuum flow problem. Mass conservation in the flow problem, and the behaviour of free edges in the two-dime…

Per un museo diffuso di arte contemporanea: il quartiere Eur a Roma. Frammenti di storia e paesaggio tra preesistenze archeologiche, architettura, ar…

2015

Abstract Obiettivi. Attraverso una lettura storico-artistica di alcuni manufatti collocati nel quartiere romano dell’Eur realizzati tra gli anni trenta e la fine degli anni novanta del Novecento, si vuole tracciare un percorso didattico, culturale e turistico che valorizzi il museo diffuso presente nel quartiere. Metodologia. La metodologia storico-artistica adottata comprende l’analisi del possibile Museo Diffuso analizzato rispetto al contesto spazio-temporale di realizzazione, il rapporto con la committenza, lo studio del profilo biografico e artistico degli autori coinvolti, il confronto con altre aree disciplinari. Risultati. L’intervento mira a tradurre i contributi scientifici sull’a…