Search results for "slip"
showing 10 items of 471 documents
Characteristics of computed tomography angiography findings of coronary arteries in patients with suspected or established familial hypercholesterole…
2021
KOPSAVILKUMS Nosaukums: Koronāro artēriju datortomogrāfiskās angiogrāfijas atrades raksturojums pacientiem ar iespējamu vai konstatētu Ģimenes Hiperholesterinēmiju. Ievads: Ģimenes hiperholesterīnēmija ir biežākais iemesls pārmantotai dislipidēmijai visā pasaulē. Slimība attīstās nemanāmi, bet pēkšņi var kļūt fatāla. Tāpēc ir svarīgi to diagnosticēt vai izvērtēt bojājumu izteiktību cik agri iespējams, pirmsaterosklerotiskiem kardiovaskulāriem notikumiem.Sķiet, ka šobrīd CT angiogrāfija ir laba metode lai raksturotu izmaiņas koronārajās artērijās ĢH pacientiem. Mērkis: Raksturot aterosklerotiskās izmaiņas ĢH pacientu koronārajās artērijās izmantojot CT angiogrāfija rezultātus. Materiāls un m…
Metabolic effects of sacubitril/valsartan: are they relevant in clinical practice?
2018
The burden of cardiometabolic diseases continues to rise worldwide (1). Obesity, insulin resistance, atherogenic dyslipidemia, hypertension and intra-abdominal adiposity are strongly interrelated and are crucial determinants of heart failure (HF) (2).
Positron Annihilation in Polycrystalline Metals Deformed by Uniaxial Tension
2005
Angular distributions of the positron annihilation quanta were measured for polycrystalline samples deformed by uniaxial tension up to difierent deformation degrees. The S parameter as a function of the W parameter was determined. The data obtained for samples elongated up to difierent elongation degrees indicate that in the proportionality and limited proportionality regions the changes in the physical properties of samples are governed mainly by generation of vacancies and formation and kinetics of transformations of vacancy clusters occurring flrst of all on the grains of monocrystallites. In the region of plastic deformations the dominant defects are dislocations and vacancies and their…
Nutraceuticals and functional foods for the control of plasma cholesterol levels. An intersociety position paper
2018
Current evidence shows that cholesterol management either reduces the likelihood of cardiovascular disease (CVD) or slows down its progression. Hence, it is important that all health professionals make appropriate use of all the available intervention strategies to control risk factors: from dietary improvement and positive lifestyle changes to the use of functional foods, food supplements, and drugs. This review examines the effect of the most frequently occurring cholesterol-lowering substances in functional foods or in supplements across Europe, namely plant sterols and stanols, monacolin K found in red yeast rice, berberine and beta-glucans. We conclude that currently available suppleme…
Heat generation associated with collision of two plates: the Himalayan geothermal belt
1998
Abstract An analysis of heat discharged by thermal fluids along the c. 3000-km-long Himalayan geothermal belt (HGB) shows that heat transfer is concentrated along 30- to 50-km-wide `heat bands' which are associated with at least 600 geothermal systems. The bands have been interpreted as segments of major, concentric slip lines caused by plastic deformation of the ductile crust within the Asian plate resulting from plate collision. Assuming that this crust behaves like an ideal plastic medium, the heat transfer within and along a slip line can be estimated. It amounts to c. 55 mW/m2 for a 40-km-wide band. Estimates of present-day heat discharges point to 20–35 mW/m2 for convective, and 10–30…
A strike-slip core complex from the Najd fault system, Arabian shield
2014
Metamorphic core complexes are usually thought to be associated with regional crustal extension and crustal thinning, where deep crustal material is exhumed along gently dipping normal shear zones oblique to the regional extension direction. We present a new mechanism whereby metamorphic core complexes can be exhumed along crustal-scale strike-slip fault systems that accommodated crustal shortening. The Qazaz metamorphic dome in Saudi Arabia was exhumed along a gently dipping jog in a crustal-scale vertical strike-slip fault zone that caused more than 25 km of exhumation of lower crustal rocks by 30 km of lateral motion. Subsequently, the complex was transected by a branch of the strike-sli…
Cross-flow Turbine Design for Variable Operating Conditions
2014
Abstract The potential energy hidden in water resources is becoming more and more a significant economic value. The value of the hydroelectric energy is often magnified by the proximity of the turbine to pumps or other energy sinks owned by the same water manager. Cross-flow or Banki-Michel turbines are a very efficient and economic choice that allows a very good cost/benefit ratio for energy production located at the end of conduits carrying water from a water source to a tank. In the paper the optimum design of a cross-flow turbine is sought after, assuming a flow rate variable in time. Regulation of the discharge entering in the turbine is a key issue, which is faced adopting a shaped se…
Dislipidēmija kā riska faktors nieru funkcionālo spēju samazinājumam I tipa cukura diabēta pacientiem
2019
Diabētiskā nefropātija ir svarīga un bieži diabēta pacienta dzīvību apdraudoša mikrovaskulāra komplikācija (Groop et al., 2009). Diabētiskās nefropātijas pacientiem dislipidēmiju sastop bieži, tomēr līdz šim veikto pētījumu rezultāti nav viennozīmīgi attiecībā uz seruma lipīdu frakciju ietekmi uz nieru funkciju. Pētījuma mērķis bija izpētīt 1. tipa cukura diabēta pacientu lipīdu un apolipoproteīnu līmeņu asociāciju ar nieru funkcionālo spēju (glomerulārā filtrācijas ātruma un albuminūrijas) samazinājumu laika gaitā. Veikts šķērsgriezuma tipa pētījums, kurā tika izmantoti 106 1. tipa cukura diabēta pacientu paraugi un klīniskie dati no „LatDiane: Latvijas diabētiskās nefropātijas pētījuma”, …
[Pharmacogenomics of antiretrovirals].
2008
HIV infection is a serious but treatable disease, yet current treatment is limited by development of resistance and high rates of adverse drug reactions. Antiretroviral therapy is especially suitable for pharmacogenomic investigation as both drug exposure and treatment response can be reliably measured. Increasing knowledge about genes implicated in pharmacokinetics, mode of action, efficacy, and toxicity of drugs has already provided relevant results for clinical practice, for example: The strong association of the abacavir hypersensitivity reaction with HLA-B*5701 permits testing patients for the allele, and if present avoiding the drug and therefore preventing the reaction. Persons with …
Egg consumption and human health: an umbrella review of observational studies
2019
Egg consumption has been an area of controversy regarding its impact on human health largely due to the content in cholesterol and its potential role in cardio-metabolic outcomes. This study aimed to summarise the level of evidence of egg consumption on various health outcomes. A systematic search for meta-analyses was performed: study design, dose-response relationship, heterogeneity and agreement of results over time, and identification of potential confounding factors were considered to assess the level of evidence. Results from this umbrella review showed a substantial no association between egg consumption and a number of health outcomes, including cancer, cardiovascular and metabolic …