Search results for "smoking."
showing 10 items of 631 documents
Resident-Initiated Smoking Ban Surveillance: Text Mining of Shanghai Public Service Hotline Data
2019
Background: On March 1st, 2017, the Amendment of Regulations of Shanghai Municipality on Smoking Control in Public Places was formalized in Shanghai. Since then, this comprehensive smoke-free law prohibits smoking in indoor public places, workplaces, and public transport. To reinforce this law, the "12345 hotline" platform was introduced as an avenue for residents to report smoking violations. Methods: Throughout March 2017, the hotline back-end server had logged a total of 6,937 telephone text records. All records were collected, and text data were analyzed by natural language processing. The analysis of text data has gone through several steps, namely data masking, missing data deletion, …
Sperm selection by swim-up in terms of deoxyribonucleic acid fragmentation as measured by the sperm chromatin dispersion test is altered in heavy smo…
2007
Toxic habits and their relationship with male factor infertility have been a matter of investigation in recent years, and smoking is one of the most common lifestyle toxic exposures to harmful substances. The analysis of sperm deoxyribonucleic acid fragmentation after capacitation detected a detrimental effect produced by tobacco, and this deleterious effect alters the sperm swim-up selection process in smokers, although the molecular and cellular basis of this phenomenon remain to be elucidated.
The impact of cigarette smoking on the health of descendants
2012
This paper presents a review of the literature on the effects of cigarette smoking on the health of descendants and the possible mechanisms that lead to them. The evidence of the effects of prenatal cigarette smoke exposure on neonatal morbidity is clear. A number of birth defects have their incidence raised by maternal cigarette smoking during pregnancy. Prenatal smoke exposure also increases the risk of infant irritability, inattention, decreased response to inanimate auditory stimuli and hypertonia. In addition, the prevalence of obesity in preschool children is higher if the mother smoked during pregnancy, as well as the presence of male or female subfertility/infertility in adult life.…
Cigarette smoke promotes inflammasome‐independent activation of caspase‐1 and ‐4 leading to gasdermin D cleavage in human macrophages
2022
Mechanisms and consequences of gasdermin D (GSDMD) activation in cigarette smoke (CS)-associated inflammation and lung disease are unknown. GSDMD is a downstream effector of caspase-1, -8, and -4. Upon cleavage, GSDMD generates pores into cell membranes. Different degrees of GSDMD activation are associated with a range of physiological outputs ranging from cell hyperactivation to pyroptosis. We have previously reported that in human monocyte-derived macrophages CS extract (CSE) inhibits the NLRP3 inflammasome and shifts the response to lipopolysaccharide (LPS) towards the TLR4-TRIF axis leading to activation of caspase-8, which, in turn, activates caspase-1. In the present work, we investig…
Cellular and Molecular Signatures of Oxidative Stress in Bronchial Epithelial Cell Models Injured by Cigarette Smoke Extract
2022
Exposure of the airways epithelium to environmental insults, including cigarette smoke, results in increased oxidative stress due to unbalance between oxidants and antioxidants in favor of oxidants. Oxidative stress is a feature of inflammation and promotes the progression of chronic lung diseases, including Chronic Obstructive Pulmonary Disease (COPD). Increased oxidative stress leads to exhaustion of antioxidant defenses, alterations in autophagy/mitophagy and cell survival regulatory mechanisms, thus promoting cell senescence. All these events are amplified by the increase of inflammation driven by oxidative stress. Several models of bronchial epithelial cells are used to study the molec…
Certain advantages of Scopus compare with Web of Science in a bibliometric analysis related to smoking
2013
El objetivo de este trabajo es comparar entre Web of Science (WoS) y Scopus los indicadores bibliométricos básicos del área de tabaquismo de autores españoles en el período 2000-2009. Métodos: La búsqueda se realizó en el SCI-Expanded y Scopus (“smok*” OR “tobac*”). Resultados: La media total anual del nº de documentos fue de 41 ± 12 para WoS vs 60 ± 16 en Scopus (p = 0,007). Aumento progresivo del índice de colaboración. La media anual del índice de colaboración fue de 9,41 ± 2,73 en WoS vs 7,12 ± 1,52 en Scopus (p = 0,029). Mayor número de citas con el paso del tiempo en ambas bases de datos pero son más recientes las citas en Scopus, el índice citas/artículo fue mayor en WoS (WoS 14,47 v…
Scientific Literature Among Smoking and Respiratory System: Repercussion and Collaboration
2012
a b s t r a c t Aim: To analyze the distribution of the production, repercussion and co-authorship of articles on smok- ing in the "respiratory system" category through the Science Citation Index Expanded (SCI-E) and their inclusion in the first quartile of the Journal Citation Report (JCR). Methods: The literature search was performed in the SCI-E. Articles were selected for 2001-2010 for "respiratory system" using the descriptors "smok*" and "tobac*". Results: We found 1858 articles (ignoring collaboration) on the topic of smoking. The median number of published articles by five-year period was higher for the 2006-2010 period vs the 2001-2005 period; in contrast, the number of citations a…
Cigarette smoke affects the onco-suppressor DAB2IP expression in bronchial epithelial cells of COPD patients
2019
AbstractCigarette smoke is a risk factor for COPD and lung cancer. In cancer, epigenetic modifications affect the expression of Enhancer of Zester Homolog 2 (EZH2), and silenced disabled homolog 2 interacting protein gene (DAB2IP) (onco-suppressor gene) by Histone H3 tri-methylation in lysine 27 (H3K27me3). In“ex vivo”studies, we assessed EZH2, H3K27me3 and DAB2IP immunoreactivity in bronchial epithelial cells from COPD patients (smokers, ex-smokers), Smoker and control subjects. In“in vitro” experiments we studied the effect of cigarette smoke extract (CSE) on EZH2/H3K27me3/DAB2IP expression, apoptosis, invasiveness, and vimentin expression in 16HBE, primary cells, and lung cancer cell lin…
Using an extended version of the theory of planned behaviour to predict smoking cessation in two age groups
2011
The aim of this study was twofold: (i) to test the utility of the theory of planned behaviour (TPB) in predicting intentions to quit smoking and subsequent behaviour in two age groups, and among women and men, and (ii) to examine whether descriptive norms, moral norms and past behaviour predict intentions and behaviour beyond the impact of the TPB components. Analyses were based on data from a prospective sample of 447 daily smokers (adolescents 16–19 years, n = 174, M = 17.5, adults 35–55 years, n = 311, M = 44 years). The TPB accounted for 31.8% and 38% of the variance in intentions in the adolescent and adult groups, respectively. The extension variables added 12.6% and 12.1% to the …
An extended version of the theory of planned behavour: Prediction of intentions to quit smoking using past behaviour as moderator
2010
It was hypothesised that: (i) intentions to quit smoking were predictable from group identity, self-identity, moral norms and past quit attempts, beyond the components of the Theory of Planned Behaviour (TPB), and (ii) that past experiences with the behaviour (quit attempts) would increase the predictive utility of the extended TPB model on intentions. The data was collected among 357 daily smoking students (M = 24 years). The TPB components accounted for 12.3% of the variance in quitting intentions, while the extension variables added 16.5% to the explained variance in intentions beyond the impact of the TPB. Past behaviour had the strongest impact on intentions (α = 0.30), followed by mor…