6533b7ddfe1ef96bd1275257

RESEARCH PRODUCT

Sperm selection by swim-up in terms of deoxyribonucleic acid fragmentation as measured by the sperm chromatin dispersion test is altered in heavy smokers.

Marcos MeseguerAntonio PellicerJosé Luis FernándezJosé RemohíThamara ViloriaNicolás Garrido

subject

InfertilityAdultMaleSperm RetrievalSemenCell SeparationDNA FragmentationFertilization in VitroBiologyMale infertilityAndrologyCapacitationmedicineHumansFragmentation (cell biology)Infertility MaleSmokingObstetrics and GynecologyMiddle Agedmedicine.diseaseSpermSpermatozoaChromatinReproductive MedicineMolecular Diagnostic TechniquesSperm RetrievalDNA fragmentationSperm Capacitation

description

Toxic habits and their relationship with male factor infertility have been a matter of investigation in recent years, and smoking is one of the most common lifestyle toxic exposures to harmful substances. The analysis of sperm deoxyribonucleic acid fragmentation after capacitation detected a detrimental effect produced by tobacco, and this deleterious effect alters the sperm swim-up selection process in smokers, although the molecular and cellular basis of this phenomenon remain to be elucidated.

yearjournalcountryeditionlanguage
2007-08-01Fertility and sterility
10.1016/j.fertnstert.2006.11.135https://pubmed.ncbi.nlm.nih.gov/17482606