Search results for "soft"

Prediction of Disease–lncRNA Associations via Machine Learning and Big Data Approaches

2021

This chapter introduces long non-coding RNAs and their role in the occurrence and progress of diseases. The discovery of novel lncRNA-disease associations may provide valuable input to the understanding of disease mechanisms at the lncRNA level, as well as to the detection of biomarkers for disease diagnosis, treatment, prognosis, and prevention. Unfortunately, due to costs and time complexity, the number of possible disease-related lncRNAs verified by traditional biological experiments is very limited. Computational approaches for the prediction of potential disease-lncRNA associations can effectively decrease the time and cost of biological experiments. We first review the main computatio…

Comparative evaluation of data preprocessing software tools to increase efficiency and accuracy in diffusion kurtosis imaging

2016

Current characterisation for ultra low power wireless body area networks

2010

The emerging area of body area networks (BAN) imposes challenging requirements on hardware and software to achieve the desired lifetimes for certain devices such as long term medical implants. In this paper, we propose a novel approach to the measurement and characterisation of the energy consumption of BAN devices. The approach uses a low cost energy auditing circuit and addresses the problem of accurately measuring low-level current consumption. This new technique will allow precise and analytical measurements of systems and components in terms of energy. This will help circuit designers minimise power consumption in BAN devices. Software engineers might use this approach to validate and …

Masonry structures subjected to tsunami loads: Modeling issues and application to a case study

2020

Abstract Tsunamis are among the most dangerous natural disasters for coastal areas experiencing tsunami hazard. One of the major concerns in the assessment of strategies for the risk mitigation is to estimate vulnerability of structures and infrastructures. However, reliable approaches for the evaluation of the structural capacity under tsunami loads are nowadays not always available for all the types of structures, especially masonry. On this aim, the paper deals with the modeling issues of 3D masonry structures subjected to tsunami loads and the effect on the structural behavior of different modeling approaches. First, a brief state of the art on the available studies is presented regardi…

Ontological Analysis and Modularization of CIDOC-CRM

2020

Conference cancelled due to COVID19; International audience; The CIDOC-CRM ontology is a standard for cultural heritage data modeling. Despite its large exploitation, the ontology is primarily maintained in a semi-formal notation, which makes it difficult to homogeneously exploit it in digital environments. In addition, the ontology consists of several classes and relations, whereas one sometimes wishes to reuse it but only partially. The purpose of the paper is to contribute to the use of CIDOC by strengthening its foundations. On the basis of formal ontology theories, we propose a first analysis of the ontology to enhance its conceptual structure. We also present a preliminary modularizat…

Optimization of a Time-to-Digital Converter and a coincidence map algorithm for TOF-PET applications

2015

This contribution describes the optimization of a multichannel high resolution Time-to-Digital Converter (TDC) in a Field-Programmable Gate Array (FPGA) initially capable of obtaining time resolutions below 100ps for multiple channels. Due to its fast propagation capability it has taken advantage of the FPGA internal carry logic for accurate time measurements. Furthermore, the implementation of the TDC has been performed in different clock regions and tested with different frequencies as well, achieving improvements of up to 50% for a pair of channels. Moreover, since the TDC is potentially going to be used in a trigger system for Positron Emission Tomography (PET), the algorithm for coinci…

Experimental evaluation of topological-based fitness functions to detect complexes in PPI networks

2012

The detection of groups of proteins sharing common biological features is an important research issue, intensively investigated in the last few years, because of the insights it can give in understanding cell behavior. In this paper we present an extensive experimental evaluation campaign aiming at exploring the capability of Genetic Algorithms (GAs) to find clusters in protein-protein interaction networks, when different topological-based fitness functions are employed. A complete experimentation on the yeast protein-protein interaction network, along with a comparative evaluation of the effectiveness in detecting true complexes on the yeast and human networks, reveals GAs as a feasible an…

Trusted Computing and DRM

2015

Trusted Computing is a special branch of computer security. One branch of computer security involves protection of systems against external attacks. In that branch we include all methods that are used by system owners against external attackers, for example Firewalls, IDS, IPS etc. In all those cases the system owner installs software that uses its own means to determine if a remote user is malicious and terminates the attack. (Such means can be very simple such as detecting signatures of attacks or very complex such as machine learning and detecting anomalies in the usage pattern of the remote user). Another branch of attacks requires protection by the system owner against internal users. …

Experimental BIM applications in Archaeology: a work-flow

2014

In the last few decades various conceptual models, methods and techniques have been studied to allow 3D digital access to Cultural Heritage (CH). Among these is BIM (Building Information Modeling): originally built up for construction projects, it has been already experimented in the CH domain, but not enough in the archaeological field. This paper illustrates a framework to create 3D archaeological models integrated with databases using BIM. The models implemented are queryable by the connection with a Relational Database Management System and sharable on the web. Parametric solid and semantic models are integrated with 3D standardized database models that are finally manageable in the pub…

Integrating Social Skills in Task-Oriented 3D IVA

2005

This paper presents a set of mechanisms oriented to incorporate social information into the decision taking of task-oriented 3DIVA. The aim of this approach is to integrate collaborative skills in different character's roles (seller/buyer, worker, pedestrian, etc.) in order to enhance its behavioral animation. The collective intelligence expected in this kind of multi-character domains (e.g. storytelling, urban simulation, interactive games, etc.) requires agents able to dialogue/interact with other characters, to autonomously group/ungroup (according to their goals), or to distribute tasks and coordinate their execution for solving possible conflicts. The social model implemented follows t…