Search results for "solid"
showing 10 items of 3575 documents
Solid and Semisolid Innovative Formulations Containing Miconazole-Loaded Solid Lipid Microparticles to Promote Drug Entrapment into the Buccal Mucosa
2021
The currently available antifungal therapy for oral candidiasis (OC) has various limita- tions restricting its clinical use, such as short retention time, suboptimal drug concentration and low patients compliance. These issues could be overcome using micro or nanotechnology. In par- ticular, solid lipid microparticles (SLMs) resulted as a particularly promising penetration enhancer carrier for lipophilic drugs, such as the antifungal miconazole (MCZ). Based on these considera- tions, cetyl decanoate (here synthesized without the use of metal catalysis) was employed together with 1-hexadecanol to prepare MCZ-loaded SLMs. These resulted in a powder composed of 45–300 µm diameter solid spheric…
Multi-residue determination of 47 organic compounds in water, soil, sediment and fish—Turia River as case study
2017
A sensitive and reliable method based on solid-liquid extraction (SLE) using McIlvaine-Na2EDTA buffer (pH = 4.5)-methanol and solid-phase extraction (SPE) clean up prior to ultra-high-performance liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS/MS) was applied to determine 47 organic contaminants in fish, soil and sediments. The SPE procedure to clean-up the extracts was also used as extraction method to determine these compounds in water. Recoveries ranged from 38 to 104% for all matrices with RSDs 50% for 36 compounds in front of 9, matrix effect < 20% for 31 compounds against 21, and LOQs <25 ng g−1 for 38 compounds against 22) indicates that the proposed method is mor…
Simultaneous determination of traditional and emerging illicit drugs in sediments, sludges and particulate matter
2015
An analytical method for determining traditional and emerging drugs of abuse in particulate matter, sewage sludge and sediment has been developed and validated. A total of 41 drugs of abuse and metabolites including cocainics, tryptamines, amphetamines, arylcyclohexylamines, cathinones, morphine derivatives, pyrrolidifenones derivatives, entactogens, piperazines and other psychostimulants were selected. Samples were ultrasound extracted with McIlvaine buffer and methanol, and the extracts were cleaned up by solid phase extraction (SPE) using Strata-X cartridges. Drugs were eluted using methanol and methanol-dichloromethane and determined by liquid chromatography tandem mass spectrometry. Th…
Ductility of Reinforced Concrete Members Externally Wrapped with Fiber-Reinforced Polymer Sheets
2007
The effectiveness of external wrapping with fiber-reinforced polymer for enhancing the curvature ductility of lightly reinforced concrete members is investigated. Referring to members with circular transverse cross sections, the performances in terms of both strength and ductility capacities are analyzed, and the predictive reliability of two different recent constitutive models, available in the literature and able to take into account the softening behavior of confined concrete, is checked. A parameter characterizing the effectiveness of the confining wrapping is proposed, and characteristic values are suggested. Moreover, referring to ductility increases due to confinement effects, a com…
The Social State Based on the Rule of Law in the Europe of Rights
2012
Chapter 8 shows how the idea of the social State under the rule of law has been linked to the European Union since its inception. The founding fathers (Adenaeur, de Gasperi, Monet, Schuman) set the principles of dignity, freedom, equality and solidarity as a way of freeing European citizens from fear, misery and misfortune. Welfare is, above all, a state of justice that defines the threshold between indecency and well-being and affirms that human development is not (only) economic growth. Jacques Maritain, whose influence on the European Union is well known, proclaimed the order that contains the three principles of the social state: the primacy of the person, the priority of civil society …
Thermal and optical properties of red luminescent glass forming symmetric and non symmetric styryl-4H-pyran-4-ylidene fragment containing derivatives
2012
Abstract Dyes with amorphous structure deposited from organic solvents and having good fluorescence properties show potential for photonic device applications. Organic glass-forming symmetric and non symmetric styryl- derivatives of 2(2,6-substituted-4H-pyran-4-ylidene)-malononitrile (it has backbone of known laser dye 4-(dicyanomethylene)-2-methyl-6-[p-(dimethylamino)styryl]-4H-pyran), 2(2,6-substituted-4H-pyran-4-ylidene)-1H-indene-1,3(2H)-dione and 2(2,6-substituted-4H-pyran-4-ylidene)-pyrimidine-2,4,6(1H,3H,5H)-trione were synthesized and investigated. Glass transition temperatures higher than 110 °C were achieved. The absorption bands in dichloromethane solution cover the spectral regi…
Solid-state diffusion phenomena in heterogeneous gas-solid reactions : Application to oxides sulfidation
2018
Phase transition phenomena involving the mobility of the reaction interface are involved in a wide variety of chemical reactions and applications. A good example is the sulfidation reaction experienced by the metal oxide-based materials used in the framework of gas purification or catalysts preparation applications. These reactions involve solid-state diffusion phenomena of the reactive species (atomic or ionic form) through the layer of product formed during the reaction (oxide, sulfide, or metal phase). In many cases, solid-state diffusion has a direct impact on the reaction mechanisms while determining the growth direction of the formed phases, as well as the overall kinetics of the reac…
Mediterranean Borders and Diaspora
2020
“And So Europe Dehumanized Itself”, the expression used by Toni Morrison regarding slavery, seems to have returned dramatically to current affairs. We seem to have plunged into a dystopian present in which the European Union, instead of governing the disruptive global migrations through appropriate policies, has expressed such nervousness – both at the popular and institutional levels – to give rise, in an unstoppable crescendo, to practices inspired by xenophobia and racism. It has led to the inhuman treatment of migrants (I refer both to shipwrecks at sea, a real massacre and to the torture and torture reserved for them in Libya with the complicity of European governments) and finally to …
Cautionnement. Cautions solidaires et débiteur principal en liquidation judiciaire. Portée du rejet d'une créance au passif d'un des cofidéjusseurs à…
2015
International audience; (Com., 18 novembre 2014, n° 13-23.976, P+B, Caisse de Crédit Mutuel Mulhouse Concorde c/ M. et Mme X., D. 2014. 2405 ; RTD com. 2015. 152, obs. A. Martin-Serf ; Gaz. Pal. 18 au 20 janv.2015, p. 33, note E. Le Corre-Broly)
Study of the high temperature behaviour of titanium alloy Ti6242S under complex atmospheres : aeronautical applications
2018
The use of titanium alloys in many applications (transport, energy, chemistry,...) allows significant weight savings in relation to the good mechanical properties/density ratio of these materials. Since titanium alloys are employed at high temperatures (T>500°C), their behavior in such conditions has to be studied in severe conditions in order to understand degradation mechanisms. Moreover, some specific conditions can be met during application, like thermal cycling, water vapour or presence of salts. These parameters are known to influence oxidation behavior of titanium alloys.In this thesis work, oxidation behavior of an aeronautics titanium alloy (Ti6242S) has been studied in air and moi…