Search results for "solu"
showing 10 items of 7577 documents
The case for simplifying and using absolute targets for viral hepatitis elimination goals
2021
The 69th World Health Assembly endorsed the Global Health Sector Strategy for Viral Hepatitis, embracing a goal to eliminate hepatitis infection as a public health threat by 2030. This was followed by the World Health Organization's (WHO) global targets for the care and management of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. These announcements and targets were important in raising awareness and calling for action; however, tracking countries’ progress towards these elimination goals has provided insights to the limitations of these targets. The existing targets compare a country's progress relative to its 2015 values, penalizing countries who started their programmes …
Structural Features of β-Cyclodextrin Solvation in the Deep Eutectic Solvent, Reline
2020
The inherently amphiphilic nature of native cyclodextrins (CDs) determines their peculiar molecular encapsulation features, enabling applications such as targeted drug nanodelivery, aroma protection, etc. On the contrary, it may also lead to poor solubility in water and other organic solvents and to potentially detrimental flocking in these media, thus posing limitations to more extensive usage. Here we use small angle X-ray scattering to show that deep eutectic solvent reline (1:2 choline chloride:urea) succeeds in dissolving large amounts of beta-CD (at least 800 mg/mL, compared with the solubility in water of 18 mg/mL), without aggregation phenomena occurring. At the microscopic level, m…
Synthesis and self-assembly of a PEGylated-graphene aerogel
2016
Abstract In the frame of this work, we present, for the first time, the synthesis and self-assembly of an aerogel built by graphene oxide-polyethylene glycol. The synthetic route involves at first the coupling of GO with an amino-terminated polyethylene glycol sample by carbodiimide in aqueous environment, and the subsequent conversion of the hydrogel achieved into an aerogel via freeze-drying. The 3D PEGylated graphene-based aerogel, characterized by spectroscopic, morphological, structural and mechanical analyses, displays an ultralight and highly porous (99.7%) network and possesses high mechanical properties together with a good biocompatibility.
The use of mineral materials for salinity control in roadside soils
2023
This paper presents the results of a fi eld study on using mineral materials (fi ne-grained sand and medium- -grained gravel) to reduce the concentration of readily soluble salts in a roadside environment. The investigated soils were Rendzic Sceletic Leptosols from an urban area characterized by a shallow humus horizon with a high content of skeletal parts, as well as a lack of homogeneity of the material in the soil profi le. All soil samples were taken from fi ve plots located along the main streets in the city of Opole (Southern Poland). It was revealed that the use of fi ne-grained sand and medium-grained gravel improved the structure of the surface soil layer, and thusfavoured the migr…
Apprendimento basato sull'indagine dei fenomeni termici di dissoluzione
2014
On Variational Measures Related to Some Bases
2000
Abstract We extend, to a certain class of differentiation bases, some results on the variational measure and the δ-variation obtained earlier for the full interval basis. In particular the theorem stating that the variational measure generated by an interval function is σ-finite whenever it is absolutely continuous with respect to the Lebesgue measure is extended to any Busemann–Feller basis.
Availability of iron from milk-based formulas and fruit juices containing milk and cereals estimated by in vitro methods (solubility, dialysability) …
2007
Abstract Iron solubility, dialysability and transport and uptake (retention + transport) by Caco-2 cells as indicators of iron availability have been estimated in the in vitro gastrointestinal digests of infant foods (adapted, follow-up and toddler milk-based formulas and fruit juices containing milk and cereals (FMC)). Low correlation coefficients (in all cases R -squared ⩽ 37.1%) were obtained between iron solubility or dialysability versus transport or uptake efficiency – a fact emphasizing the importance of incorporating Caco-2 cell cultures to in vitro systems in order to adapt the conditions to those found in in vivo assays. The highest uptake efficiency corresponded to FMC (25.6–26.1…
Value Co-Creation Opportunities: Managerial Transformation of Digitisation Risks into Success Factors
2018
This chapter examines the challenges and risks managers in the healthcare sector perceive in relation to the development and implementation of digitised services in a healthcare case organisation. Using data collected from managers, focus group interviews and observation method within the case organisation, the authors present an analysis that demonstrates that the risks and success factors that influence the development and implementation of digital healthcare services are related to (1) setting a clear digital strategy and implementation plan, (2) integration of digital services with the overall process and ICT, (3) committed resources and engagement of personnel, and (4) the organisation…
La dirigenza pubblica: criteri di identificazione e specialità della disciplina.
Nel tentativo di far luce sui maggiori coni d’ombra che emergono dalla relativa disciplina speciale del rapporto di lavoro, la tesi riflette l’esigenza di un ripensamento sistematico della figura del dirigente pubblico, nell’ottica di prospettare de iure condendo possibili correttivi. A tal fine, sono analizzate le peculiarità ed attribuzioni della dirigenza pubblica, in chiave storico-evolutiva, alla luce dei principi costituzionali e del processo riformatore che ha contrassegnato la magmatica materia, a tutt’oggi in atto. E’, altresì, rivolto uno sguardo comparativistico alla disciplina del personal directivo español, rivelandosi la stessa, speculare a quella del dirigente italiano quanto…
Inadempimento anticipato e risoluzione del contratto
2021
Le disposizioni di cui agli artt. 1453 e 1455 c.c. individuano una fattispecie alla quale l’ordinamento ricollega in via generale il diritto del contraente alla risoluzione del contratto. Numerosi sono i tentativi di ridefinizione di questa fattispecie. In particolare, tra le varie questioni che tuttora si pongono sul punto, una non risulta ancora chiarita del tutto. Il riferimento è alla collocazione temporale dell’inadempimento; in altri termini, se gli artt. 1453 ss. c.c. richiedono necessariamente che si tratti di un inadempimento successivo alla scadenza del termine o al verificarsi della condizione (sospensiva), quando nel contratto è presente uno di quegli elementi accidentali. Il co…