Search results for "solutions"

Maltose-conjugated chitosans induce macroscopic gelation of pectin solutions at neutral pH

2014

Injectable polymer scaffolds are particularly attractive for guided tissue growth and drug/cell delivery with minimally invasive intervention. In the present work, "all-polymeric" gelling systems based on pectins and water-soluble maltose-conjugated chitosans (CM) have been developed. Maltose-conjugated chitosan has been synthesized at three different molar ratios, as evaluated by FITR analysis and fluorimetric titration. A thorough rheological characterization of the blends and their parent solutions has been performed. Macroscopic gelation has been achieved by mixing the high esterification degree pectins with CM at higher maltose grafted to chitosan contents. Gels form in a few minutes a…

Molecular insights into shellac film coats from different aqueous shellac salt solutions and effect on disintegration of enteric-coated soft gelatin …

2014

The purpose of this investigation was to study the effect of using different salts of shellac on the disintegration properties of shellac-based enteric coatings. In the last two decades, shellac has been increasingly used as an aqueous solution for enteric coating purposes, with the ammonium salt being the form typically used. Little investigation has been performed on using other salts, and therefore, this was the focus of our work. Enteric coatings, based on different shellac salts (ammonium, sodium, potassium and composite ammonium-sodium), were applied onto soft gelatin capsules. Disintegration testing of the coated soft gelatin capsules showed that alkali metal salts promote faster dis…

Digital solutions transform the forest-based bioeconomy into a digital platform industry : a suggestion for a disruptive business model in the digita…

2018

With the notion that the transformation of the forest-based bioeconomy in recent years provides insightful suggestions not only on the bioeconomy, but on business innovation, this paper conducts an empirical analysis of the transformation and attempts to extract suggestions for a digital-solution-driven, disruptive business model in the digital economy. Notwithstanding the potential broad cross-sectoral benefits, the natural environment, locality constraints, and incessant challenge of distance have impeded the balanced development of the bioeconomy. However, driven by digital solutions, the bioeconomy has taken big steps forward in recent years. Digitalization has enabled real-time, end-to…

Digital Solutions in the Forest-Based Bioeconomy

2019

This chapter aims to illustrate the potential and significance of forest-based industry to take the lead in the sustainable development of the bio-based economy under digitalization. The digital solutions are transforming the forest-based industry by enabling the real-time end-to-end supply chain visibility, stock level optimization, demand planning, and real-time order status tracking and transparent, speedy, and hassle-free order fulfillment. In addition, increasing diversification corresponds to eco-consciousness, and shift in people’s preferences induces the transformation of forest-based bioeconomy into a digital platform industry. Further, this chapter will highlight the circular econ…

Spherical harmonic expansion of fundamental solutions and their derivatives for homogenous elliptic operators

2017

In this work, a unified scheme for computing the fundamental solutions of a three-dimensional homogeneous elliptic partial differential operator is presented. The scheme is based on the Rayleigh expansion and on the Fourier representation of a homogeneous function. The scheme has the advantage of expressing the fundamental solutions and their derivatives up to the desired order without any term-by-term differentiation. Moreover, the coefficients of the series need to be computed only once, thus making the presented scheme attractive for numerical implementation. The scheme is employed to compute the fundamental solution of isotropic elasticity showing that the spherical harmonics expansions…

Penetration of 2% cyclosporin eyedrops into human aqueous humour.

1989

The penetration into the eye and the systemic absorption of 2% cyclosporin eye drops were determined by polarisation immunofluorescent assay of cyclosporin in the aqueous humour and plasma of 30 patients at the time of cataract surgery. The results were then compared with the corresponding results after oral administration at a dosage of 5 mg/kg/day to three further patients. The maximum intraocular concentration (24 (SD 9) mg/l) was achieved four hours after topical administration. This level was slightly less than that found in aqueous humour (28 (SD 10) mg/l) 12 hours after systemic administration of the drug at a dosage of 5 mg/kg/day. Both these levels are below the minimum therapeutic…

Up-wind difference approximation and singularity formation for a slow erosion model

2020

We consider a model for a granular flow in the slow erosion limit introduced in [31]. We propose an up-wind numerical scheme for this problem and show that the approximate solutions generated by the scheme converge to the unique entropy solution. Numerical examples are also presented showing the reliability of the scheme. We study also the finite time singularity formation for the model with the singularity tracking method, and we characterize the singularities as shocks in the solution.

Multilayer blue-green roofs as nature-based solutions for water and thermal insulation management

2022

Abstract Green roofs have been widely recognized as sustainable nature-based solutions to mitigate floods in urban areas, which, in the last decades, are increasing due to the combination of intense worldwide urbanization and climate change. Besides flood mitigation, green roofs provide additional benefits for the urban environment (e.g., reducing the urban heat island and ensuring energy saving for the underneath building). Moreover, green roofs facilitate the increase of urban biodiversity, attracting different species of small animals, and upgrade the city aesthetic value. Among the different types of green roofs, multilayer blue-green roofs present an additional layer to store water dur…

Pedagogy in ECEC : Nordic Challenges and Solutions. Seminar Report, Helsinki Finland, 22 September 2016

2017

Some remarks on nonlinear elliptic problems involving Hardy potentials

2007

In this note we prove an Hardy type inequality with a remainder term, where the potential depends only on a group of variables. Such a result allows us to show the existence of entropy solutions to a class of elliptic P.D.E.'s.