Search results for "sonography"

Plerixafor is effective and safe for stem cell mobilization in heavily pretreated germ cell tumor patients.

2010

Up to 10% of germ cell tumor patients require salvage high-dose chemotherapy with stem cell support, achieving cure rates in the range of 10-60%. Stem cell mobilization may be difficult in these patients because of multiple lines of treatment known to seriously hamper stem cell recovery. Plerixafor significantly enhances the success of the CD34+ cell harvest, even in cases where prior mobilization attempts have failed. Six germ cell tumor patients provided informed consent and were included in the compassionate use program. All patients were heavily pretreated, with a median of 3.5 prior lines of therapy. All failed prior mobilization with G-CSF in combination with chemotherapy. Five patien…

Neoadjuvant bevacizumab and anthracycline-taxane-based chemotherapy in 678 triple-negative primary breast cancers; results from the geparquinto study…

2013

Abstract Background We evaluated the pathological complete response (pCR) rate after neoadjuvant epirubicin, (E) cyclophosphamide (C) and docetaxel containing chemotherapy with and without the addition of bevacizumab in patients with triple-negative breast cancer (TNBC). Patients and methods Patients with untreated cT1c-4d TNBC represented a stratified subset of the 1948 participants of the HER2-negative part of the GeparQuinto trial. Patients were randomized to receive four cycles EC (90/600 mg/m2; q3w) followed by four cycles docetaxel (100 mg/m2; q3w) each with or without bevacizumab (15 mg/kg; q3w) added to chemotherapy. Results TNBC patients were randomized to chemotherapy without (n =…

Blood flow and oxygenation status of human tumors. Clinical investigations.

1999

There is a large body of evidence suggesting that blood flow and oxygenation of human tumors are important research topics which may explain, in particular, resistance to radiation and to many antineoplastic drugs, which can limit the curability of solid tumors by radiotherapy and chemotherapy.This manuscript reviews the clinical investigations which have been performed regarding blood flow and oxygenation status of human tumors in radiation oncology.The possible uses and limitations of the prognostic significance and the changes under therapy measuring blood flow and oxygenation in human tumors were discussed. In addition, several approaches were summarized, which can improve the microvasc…

Screening for renal cell carcinoma using ultrasonography: a feasibility study

2004

Coloboma retinocoroideo: estudio mediante retinografía, angiografía fluoresceínica, ecografía y tomografía de coherencia óptica

2018

Depth determination of skin cancers treated with superficial brachytherapy: ultrasound vs. histopathology

2014

Purpose: The purpose of this study is to compare high frequency ultrasonography (HFUS) and histpathologic assessment done by punch biopsy in order to determine depth of basal cell carcinoma (BCC), in both superficial and nodular BCCs prior to brachytherapy treatment. Material and methods: This study includes 20 patients with 10 superficial and 10 nodular BCCs. First, punch biopsy was done to confirm the diagnosis and to measure tumour depth (Breslow rate). Subsequently, HFUS was done to measure tumour depth to search for correlation of these two techniques. Results: Neither clear tendency nor significance of the punch biopsy vs. HFUS depth determination is observed. Depth value differences …

Determination of the facial/oral alveolar crest using RF-echograms. An in vitro study on the periodontium of pigs.

1989

Abstract This study is a part of a research project in which we have been investigating the use of the ultrasonic pulse echo technique as a means of determining in vivo the facial/oral alveolar crest precisely and routinely. Here, RF-echograms are presented, showing the facial/oral periodontium of pigs. These echograms have been produced using a focussed 20 MHz transducer and a special design of an ultrasonic measuring and analysis system. In one series of measurements on macerated periodontia of pigs we found out that RF-echograms characteristic of a particular level of the facial/oral pericrestal aspect can be achieved. Based upon these results, we succeeded in determining exactly the hei…

Ultrasonic B-scans of the facial/oral periodontium in pigs.

1989

In vitro ultrasonic scans of the oral/facial periodontium of pigs were obtained using a special experimental design and with the help of a newly developed ultrasonic measuring and analysis system. These two-dimensional images distinguish themselves from the one-dimensional RF-echograms and A-scans in that they enable the viewer to have a quick overview of the relationship between different interfaces in a scanned sector. A selection of ultrasonic B-scans proves that the scanned tissues such as gingiva, bone, periodontal ligament, tooth surface and even structures of the inner part of the tooth may be clearly imaged and distinctly differentiated. Furthermore, we demonstrate with manipulation…

What Ingredients are Essential for the Recipe of a Study?

2019

In this investigation [1], the authors evaluated among other objectives, the analgesic efficacy and the duration of analgesia from a cohort of 60 patients for arthroscopic shoulder surgery. The gro...

B-mode versus A-mode ultrasonographic measurements of mucosal thickness in vivo

2002

Abstract Objective: The objective of this study was to compare the measurement accuracy of A-mode and B-mode ultrasonographic assessments of palatal masticatory mucosal thickness in vivo. Study Design: Thickness of palatal masticatory mucosa in the molar region of 50 volunteers was measured once with a B-mode ultrasound device (10 MHz) combined with a standoff for intraoral applications. At identical reading points thickness was also assessed with an A-mode device (5 replicates) and by needle probing for determination of true thickness. Results: On average true thickness ranged between 2.9 and 3.3 mm (95% confidence intervals; median, 3.1 mm). B-mode ultrasonography overestimated truth by 0…