Search results for "spinal cord"

showing 10 items of 302 documents

Metastatic spinal cord compression--options for surgical treatment.

1993

Fourty-three cases with metastatic spinal cord compression were reviewed post-operatively to clarify the usefulness of the procedures concerning restoration of neurological function, and pain relief. Only patients with pathological spinal instability and neurological sequelae were included. Posterior decompression and stabilization was performed in all but six patients. All but four patients (91%) reported decrease of pain symptoms. Amelioration of neurological function was achieved in 58%. Re-establishment of walking ability was obtained in 57%. Post-surgery life expectancy averaged 11 months. In patients with widespread metastatic disease and/or multi-level instability of the spine restri…

AdultMalemedicine.medical_specialtyNeurologyThoracic VertebraeCentral nervous system diseasePostoperative ComplicationsSpinal cord compressionmedicineHumansNeuroradiologyAgedAged 80 and overNeurologic ExaminationLumbar VertebraeSpinal Neoplasmsmedicine.diagnostic_testbusiness.industryInterventional radiologyMiddle AgedSpinal cordmedicine.diseaseMagnetic Resonance ImagingSurgerymedicine.anatomical_structureSpinal FusionSurgeryFemaleNeurology (clinical)NeurosurgeryComplicationbusinessTomography X-Ray ComputedSpinal Cord CompressionActa neurochirurgica
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Benign and Atypical Meningioma Metabolic Signatures by High-Resolution Magic-Angle Spinning Molecular Profiling

2008

Meningiomas are neoplasms that arise from the leptomeningeal covering of the brain and spinal cord, accounting for 15%-20% of CNS tumors. The WHO classifies meningiomas into three histological grades: benign, atypical, and anaplasic in accordance with the clinical prognosis. Atypical and anaplasic meningiomas tend to recur. Sometimes, meningiomas with histological diagnosis of benign meningioma show clinical characteristics of atypical meningioma. In this context, high-resolution magic-angle spinning (HR-MAS) spectroscopy of intact tissue from brain tumor biopsies has shown great potential as a support diagnostic tool. In this work, we show differences between benign and atypical meningioma…

AdultMalemedicine.medical_specialtyPathologyMagnetic Resonance SpectroscopyBrain tumorHigh resolutionBiologyMalignancyBiochemistryMeningiomaInternal medicineBiomarkers TumorMeningeal Neoplasmsotorhinolaryngologic diseasesmedicineHumansneoplasmsAgedAged 80 and overPrincipal Component AnalysisGene Expression ProfilingAtypical meningiomaGeneral ChemistryMiddle Agedmedicine.diseaseSpinal cordnervous system diseasesGene expression profilingEndocrinologymedicine.anatomical_structureBenign MeningiomaFemaleMeningiomaJournal of Proteome Research
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The Prevalence of Chronic Cerebrospinal Venous Insufficiency in Meniere Disease: 24-Month Follow-up after Angioplasty

2016

Abstract Purpose To evaluate relationship between Meniere disease (MD) and chronic cerebrospinal venous insufficiency (CCSVI) using ultrasound, magnetic resonance (MR) imaging, and venography and to evaluate the effectiveness of angioplasty of the internal jugular vein (IJV) and azygos vein (AV) in reducing symptoms of MD. Materials and Methods Patients with a confirmed diagnosis of MD unresponsive to standard treatment underwent duplex ultrasound and MR imaging to diagnose CCSVI. Healthy volunteers were also studied to evaluate CCSVI in asymptomatic subjects. Patients with CCSVI and MD underwent venography and percutaneous transluminal angioplasty (PTA) of IJV and AV. Results There were 18…

AdultMalemedicine.medical_specialtyPercutaneousTime Factorsmedicine.medical_treatmentVenographyAsymptomaticMagnetic resonance angiography03 medical and health sciences0302 clinical medicineRisk FactorsAngioplastymedicinePrevalenceHumansRadiology Nuclear Medicine and imaging030223 otorhinolaryngologyInternal jugular veinMeniere DiseaseAgedUltrasonography Doppler Duplexmedicine.diagnostic_testbusiness.industryPhlebographyMiddle Agedmedicine.diseaseSurgeryChronic cerebrospinal venous insufficiencyCerebrovascular DisordersTreatment OutcomeItalySpinal CordVenous InsufficiencyAzygos VeinCase-Control StudiesChronic DiseaseFemaleMeniere Diseasevenous insufficiencyRadiologymedicine.symptomAzygos veinJugular VeinsCardiology and Cardiovascular Medicinebusiness030217 neurology & neurosurgeryAngioplasty BalloonMagnetic Resonance Angiography
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Motivation to Physical Exercise in Manual Wheelchair Users With Paraplegia

2020

Background: Motivation could be considered as a critical factor for being and staying physically active in the spinal cord–injured population. Objectives: Our goals were (1) to describe motivation to exercise in people with paraplegia, comparing those who engage in regular physical exercise with those who do not and (2) to establish whether such motivation is related to the type of physical exercise practiced. Methods: This study was quantitative, cross-sectional descriptive research. One-hundred and six participants with chronic paraplegia completed the Spanish version of the Exercise Motivations Inventory (EMI-2). Participants were divided into the non-exerciser group (NEG) and the exerc…

AdultMalemedicine.medical_specialtyPopulationPhysical Therapy Sports Therapy and RehabilitationPhysical exerciseManual wheelchairWheelchairSurveys and QuestionnairesHumansMedicineeducationExerciseSpinal Cord InjuriesParaplegiaMotivationeducation.field_of_studybusiness.industryRehabilitationFlexibility (personality)ArticlesMiddle AgedChronic paraplegiamedicine.diseaseCross-Sectional StudiesWheelchairsPhysical therapyFemaleNeurology (clinical)businessParaplegiaHealthcare providersTopics in Spinal Cord Injury Rehabilitation
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Cervical Spondylotic Myelopathy: When and Why the Cervical Corpectomy?

2020

Background: Cervical spondylotic myelopathy (CSM) is a degenerative disease that represents the most common spinal cord disorder in adults. The best treatment option has remained controversial. We performed a prospective study to evaluate the clinical, radiographic, and neurophysiologic outcomes for anterior cervical corpectomy in the treatment of CSM. Methods: From January 2011 to January 2017, 60 patients with CSM were prospectively enrolled in the present study. The patients were divided according to the modified Japanese Orthopaedic Association scale (mJOA) score into 2 groups: group A, patients with mild to moderate CSM (mJOA score ≥13); and group B, patients with severe myelopathy (mJ…

AdultMalemedicine.medical_specialtyRadiographymedicine.medical_treatmentSpinal Cord DisorderIntervertebral Disc DegenerationOssification of Posterior Longitudinal LigamentSeverity of Illness IndexMyelopathyYoung AdultDegenerative diseaseSpondylotic myelopathySymptom durationMedicineHumansProspective StudiesCorpectomyProspective cohort studyCervical corpectomy Young Adult Cervical spondylotic myelopathy Degenerative cervical myelopathy Surgical outcomes Adult Aged Cervical Vertebrae Decompression Surgical Functional Status Intervertebral Disc Degeneration Female Intervertebral Disc Displacement Humans Ossification of Posterior Longitudinal Ligament Middle Aged Male Prospective Studies Spinal Cord Compression Severity of Illness Index Treatment Outcome Spinal Fusion SpondylosisAgedbusiness.industryMiddle Agedmedicine.diseaseDecompression SurgicalSurgeryFunctional StatusSpinal FusionTreatment OutcomeCervical VertebraeSurgeryFemaleNeurology (clinical)SpondylosisbusinessSpinal Cord CompressionIntervertebral Disc DisplacementWorld neurosurgery
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Transverse sacral fracture with intrapelvic intrusion of the lumbosacral spine: case report and review of the literature.

2000

AdultMalemedicine.medical_specialtySacrumLumbosacral spineCritical Care and Intensive Care MedicineIntrusionFracture Fixation InternalFractures BoneMedicineHumansSpinal Cord InjuriesPelvic girdleLumbar Vertebraebusiness.industryLaminectomyAnatomySacrumSacral fractureRadiographyOrthopedic surgerySpinal FracturesSurgeryLumbar spinebusinessBone PlatesLumbosacral jointThe Journal of trauma
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Heart rate variability in individuals with thoracic spinal cord injury

2014

Cross-sectional study. The main goal of our study was to explore the differences in heart rate variability (HRV) while sitting between able-bodied (AB) participants and paraplegic (P) individuals. The study was conducted in the Physical Therapy department and the Physical Education and Sports department of the University of Valencia and Vall d’Hebron Hospital. To record the HRV, a 1000-Hz Suunto Oy t6 heart rate monitor was used. The data were analyzed in the temporal and frequency domains, and nonlinear analysis was performed as well. We found significant differences between P and AB participants in SDNN: t(76)=2.81, P<0.01; root mean squared of the difference of successive RR intervals: t…

AdultMalemedicine.medical_specialtySittingThoracic VertebraeHeart RateInternal medicinemedicineHumansHeart rate variabilityCardiac vagal toneSpinal Cord InjuriesSedentary lifestyleParaplegiaFourier Analysisbusiness.industryHeart rate monitorGeneral MedicineMiddle AgedCross-Sectional StudiesNeurologyCardiologyFemaleNeurology (clinical)businessThoracic spinal cord injurySpinal Cord
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Steroids in Acute Spinal Cord Injury: All But Gone Within 5 Years.

2019

Background Spinal cord injury (SCI) is a devastating event often leading to poor neurologic outcomes. One of the most widely practiced treatments has been the administration of methylprednisolone. However, today its use has been called into question over concerns of efficacy and safety. The present study evaluated the changes in the practice of steroid administration in acute SCI among members of the National Spinal Society in Poland in comparison with the results of the survey conducted in 2013. Methods The questionnaire, comprising 5 questions, was distributed among 240 spinal surgeons, members of the Polish Society of Spinal Surgery; of these, 97 (40%) responded. The results were compare…

AdultMalemedicine.medical_specialtyTime FactorsAnti-Inflammatory AgentsSpinal cord injuryMethylprednisolone03 medical and health sciences0302 clinical medicineAge groupsSurveys and QuestionnairesMedicineHumansSurveySpinal cord injurySpinal Cord Injuriesbusiness.industryMiddle Agedmedicine.diseaseSpinal surgeryCritical appraisalNeurosurgeonsMethylprednisoloneClinical evidence030220 oncology & carcinogenesisEmergency medicineAcute spinal cord injurySurgeryFemaleSteroidsNeurology (clinical)Polandbusiness030217 neurology & neurosurgerymedicine.drugWorld neurosurgery
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Does Hybrid Surgery Improve Quality of Life in Multilevel Cervical Degenerative Disk Disease? Five-Year Follow-up Study.

2020

Background: Patient satisfaction is becoming an increasing factor worthy of consideration when evaluating the surgical quality. The correlation between patient satisfaction and surgical outcomes 5 years after cervical hybrid surgery (HS), which incorporates anterior cervical decompression and fusion and cervical disk arthroplasty techniques in multilevel cervical degenerative disk disease, has not been evaluated. Methods: The aim of this study was firstly to analyze prospectively collected data from a sample of patients (n = 50) treated with cervical HS for selected cases of radiculopathy and myelopathy in order to evaluate pain levels of patients, using the Neck and Arm Pain scale as an ex…

AdultMalemedicine.medical_specialtyTotal Disc ReplacementVisual analogue scalemedicine.medical_treatmentDiseaseIntervertebral Disc DegenerationFunctional score03 medical and health sciencesMyelopathyAnterior cervical diskectomy fusion0302 clinical medicinePatient satisfactionPostoperative ComplicationsQuality of lifemedicineHumansRadiculopathyAgedbusiness.industryPain scaleMiddle AgedArtificial disk replacementmedicine.diseaseDecompression SurgicalArthroplastyCombined Modality TherapyMagnetic Resonance ImagingSurgerySpinal FusionTreatment OutcomePatient Satisfaction030220 oncology & carcinogenesisOrthopedic surgeryCervical VertebraeQuality of LifeSurgeryFemaleNeurology (clinical)businessDeglutition DisordersSpinal Cord CompressionHybrid surgery030217 neurology & neurosurgeryFollow-Up StudiesWorld neurosurgery
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Burkitt lymphoma associated with human immunodeficiency virus infection and pulmonary tuberculosis: A case report.

2019

Abstract Introduction: The association of human immunodeficiency virus (HIV) infection with Burkitt lymphoma is related to the presence of Epstein Barr virus infection and the impact of the HIV antigen on the expansion of B-polyclonal cells. In Southeast Europe, the association is rare, and recognizing this is important in the therapeutic decision to increase patient survival rate. The association of HIV with Burkitt lymphoma and tuberculosis is even more rarely described in the literature. Patient concerns: We present the case of a 40-year-old patient who presented with a 3-week history of fever (max. 38.7 °C), painful axillary swelling on the right side, lumbar pain, gait disorders, heada…

AdultMalemedicine.medical_specialtyTuberculosisAntitubercular AgentsAntineoplastic AgentsHIV Infectionshuman immunodeficiency virus infectionNeurosurgical ProceduresMycobacterium tuberculosis03 medical and health sciences0302 clinical medicinePharmacotherapyFatal Outcomeimmune system diseasesInternal medicinehemic and lymphatic diseasesAntiretroviral Therapy Highly ActivemedicineHumans030212 general & internal medicineClinical Case ReportEpstein–Barr virus infectionTuberculosis PulmonaryImmunodeficiencydose-adjusted etoposide doxorubicin and cyclophosphamide with vincristine prednisone and rituximabbiologyClinical Deteriorationbusiness.industry4900BrainBurkitt lymphomaGeneral MedicineViral Loadhighly active antiretroviral therapymedicine.diseasebiology.organism_classificationDecompression SurgicalLymphomaCD4 Lymphocyte CountSpinal Cord030220 oncology & carcinogenesisSputummedicine.symptombusinessViral loadpulmonary tuberculosisResearch ArticleMedicine
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