Search results for "spray drying"

showing 10 items of 42 documents

Properties of spray-dried food flavours microencapsulated with two-layered membranes: Roles of interfacial interactions and water

2012

International audience; Engineering the interface of oil-in-water emulsion droplets with biopolymers that modify its permeability could provide a novel technique to improve flavour retention in dry powders. The objective of this study was to determine if volatile compounds were more retained in dry emulsions stabilized by pea protein isolate (PPI)/pectin complex than that stabilized by PPI alone. The retention of ethyl esters during spray-drying increased with decreasing volatility of the encapsulated compound and ranged from 28% to 40%. The addition of pectin to feed emulsions was quite effective in markedly improving the retention of the three studied flavour compounds. In our previous wo…

Chromatographyfood.ingredientPectinWater activityChemistryPea proteinFlavourSpray-dryingfood and beveragesGeneral MedicineFood chemistrycomplex mixturesMultilayer emulsionsAnalytical ChemistryfoodMembraneSpray dryingReleaseEmulsionFlavours[SDV.IDA]Life Sciences [q-bio]/Food engineering[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringMicroencapsulationFood ScienceWater activity
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Encapsulation of Alcohol Dehydrogenase in Mannitol by Spray Drying

2014

The retention of the enzyme activity of alcohol dehydrogenase (ADH) has been studied in various drying processes such as spray drying. The aim of this study is to encapsulate ADH in mannitol, either with or without additive in order to limit the thermal denaturation of the enzyme during the drying process. The retention of ADH activity was investigated at different drying temperatures. When mannitol was used, the encapsulated ADH was found inactive in all the dried powders. This is presumably due to the quick crystallization of mannitol during spray drying that resulted in the impairment of enzyme protection ability in comparison to its amorphous form. Maltodextin (dextrose equivalent = 11)…

Dextrose equivalentlcsh:RS1-441Pharmaceutical ScienceArticlelaw.inventionlcsh:Pharmacy and materia medicachemistry.chemical_compoundlawmedicinespray dryingCrystallizationAlcohol dehydrogenasechemistry.chemical_classificationChromatographybiologyChemistryalcohol dehydrogenasemannitolMaltodextrinEnzyme assayEnzymeBiochemistrySpray dryingalcohol dehydrogenase; encapsulation; spray drying; mannitolbiology.proteinencapsulationMannitolhormones hormone substitutes and hormone antagonistsmedicine.drugPharmaceutics
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EPR Studies of Oxidation of Iron and Free Radicals Formation after Dessication of Oxyhemoglobin by Freeze-Drying and Spray-Drying

1992

Dans les Centres de Transfusion Sanguine, les hematies a peremption sont inutilisables. Elles peuvente transformees en solution d’hemoglobine en vue d’une utilisation potentielle pour transfuser, mais cela suppose, pour ce type de produit sanguin que les problemes de conservation resultant de l’oxydation de Fe(II) de I’heme soient resolus. Pour minimiser ce phenomene, on a voulu dessecher des preparations d’hemoglobines seules ou en presence de protecteur par differentes techniques a caractere industriel en vue d’etudier les produits formes au cours de ces traitements de dessiccation.

Freeze-dryinglawChemistrySpray dryingRadicalDesiccationElectron paramagnetic resonanceNuclear chemistrylaw.invention
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Effects of Ethanol to Water Ratio in Feed Solution on the Crystallinity of Spray-Dried Lactose

2002

In the present study, the effects of ethanol to water ratio in feed solution on the physical properties of spray-dried alpha-lactose monohydrate were evaluated. Crystallinity of the spray-dried lactose was determined by isothermal microcalorimetry (IMC) and by differential scanning calorimetry (DSC). Water content of the spray-dried lactose was determined by thermogravimetric analysis and the surface area was evaluated by Brunauer, Emmett, and Teller (BET) method. The crystallinity of spray-dried lactose varied from 0% to 100%, depending on the ratio of ethanol to water in the feed solution. Lactose spray dried from pure ethanol was 100% crystalline and contained hydrate water. Lactose spra…

Isothermal microcalorimetryStereochemistryChemistry PharmaceuticalPharmaceutical ScienceLactoseCalorimetrychemistry.chemical_compoundCrystallinityDifferential scanning calorimetryparasitic diseasesDrug DiscoveryLactoseWater contentPharmacologyEthanolOrganic ChemistryWaterPharmaceutical SolutionschemistrySpray dryingThermogravimetryMicroscopy Electron ScanningCrystallizationHydrateSurface waterNuclear chemistryDrug Development and Industrial Pharmacy
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Influence of the drying processes of yeasts on their volatile phenol sorption capacity in model wine.

2009

International audience; Volatile phenols, such as 4-ethylphenol, are responsible for a "horsey" smell in wine. Thus, the study of volatile phenol sorption in yeasts, and their subsequent elimination from wine, helps to optimize eco-friendly wine curative processes. Here, we compared the influences of spray drying, lyophilization and evaporative drying at low water activity on yeast, for improving the 4-ethylphenol sorption capacity in a synthetic model wine. The changes that occur in the physico-chemical characteristics of the yeast surface (surface hydrophobicity, electron-donor character and zeta potential) during these drying processes were determined to assess if any correlation exists …

MESH : PhenolsWater activityMESH : WineMESH : Saccharomyces cerevisiaeElectronsWineSaccharomyces cerevisiaeMESH : Models BiologicalMicrobiologyModels Biologicalcomplex mixturesMembrane Potentialschemistry.chemical_compoundFreeze-dryingPhenols4-ethylphenolMESH : AdsorptionZeta potentialMESH : Membrane PotentialsFood scienceDesiccation[ SDV.BBM ] Life Sciences [q-bio]/Biochemistry Molecular BiologyDrying processesWine4-EthylphenolChromatographyWaterSorptionGeneral MedicineMESH : Freeze DryingYeastYeastMESH : WaterFreeze DryingchemistrySpray dryingMESH : DesiccationSorptionAdsorptionMESH : HydrophobicityMESH : ElectronsHydrophobic and Hydrophilic InteractionsFood Science
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Spray-Drying, Solvent-Casting and Freeze-Drying Techniques: a Comparative Study on their Suitability for the Enhancement of Drug Dissolution Rates.

2019

Purpose Solid dispersions (SDs) represent the most common formulation technique used to increase the dissolution rate of a drug. In this work, the three most common methods used to prepare SDs, namely spray-drying, solvent-casting and freezedrying, have been compared in order to investigate their effect on increasing drug dissolution rate. Methods Three formulation strategies were used to prepare a polymer mixture of polyvinyl-alcohol (PVA) and maltodextrin (MDX) as SDs loaded with the following three model drugs, all of which possess a poor solubility: Olanzapine, Dexamethasone, and Triamcinolone acetonide. The SDs obtained were analysed and compared in terms of drug particle size, drug-lo…

Materials scienceDrug Compoundingdissolution rate . freeze-drying . solid dispersion . solvent-casting method . spray-dryingPharmaceutical Science02 engineering and technology030226 pharmacology & pharmacyTriamcinolone AcetonideDexamethasoneExcipients03 medical and health sciencesFreeze-dryingchemistry.chemical_compound0302 clinical medicinePolysaccharidesPharmacology (medical)Dissolution testingSolubilityDesiccationDissolutionPharmacologyOrganic Chemistry021001 nanoscience & nanotechnologyMaltodextrinSolventDrug LiberationFreeze DryingChemical engineeringchemistryPharmaceutical PreparationsSolubilityOlanzapineSpray dryingPolyvinyl AlcoholSolventsMolecular MedicineParticle size0210 nano-technologyBiotechnologyPharmaceutical research
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Applications of spray-drying in microencapsulation of food ingredients: An overview

2007

International audience; Spray-drying process has been used for decades to encapsulate food ingredients such as flavors, lipids, and carotenoids. During this drying process, the evaporation of solvent, that is most often water, is rapid and the entrapment of the interest compound occurs quasi-instantaneously. This required property imposes a strict screening of the encapsulating materials to be used in addition to an optimization of the operating conditions. Likewise, if the encapsulated compound is of hydrophobic nature, the stability of the feed emulsion before drying should also be considered. Thus, spray-drying microencapsulation process must rather be considered as an art than a science…

Materials scienceProcess (engineering)business.industrySpray-dryingWall materialRequired propertyIngredientScientific methodMass transferSpray drying[SDV.IDA]Life Sciences [q-bio]/Food engineeringEmulsionFood applicationsWall materialCoreFood scienceMicroencapsulationProcess engineeringbusinessFood ScienceFood Research International
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Spherical silica agglomerates possessing hierarchical porosity prepared by spray drying of MCM-41 and MCM-48 nanospheres

2003

Hierarchically ordered porous materials possessing both meso- and macropores can be obtained by agglomeration of spherical primary particles of mesoporous MCM-41 and MCM-48 materials using the spray drying technique. A highly interconnected bimodal pore network is obtained due to the intra- and inter-particle pore systems within the micron-sized spherical agglomerates. Further packing of the agglomerates will result in a three-modal hierarchical pore system, where the first level of porosity originates from the ordered mesopores inside the primary particles, the second level is a result of the particle internal porosity, and the third level is due to the voids between the agglomerates. The …

Materials scienceScanning electron microscopeSmall-angle X-ray scatteringMineralogyGeneral ChemistryPorosimetryCondensed Matter PhysicsChemical engineeringMechanics of MaterialsTransmission electron microscopySpray dryingParticleGeneral Materials SciencePorosityMesoporous materialMicroporous and Mesoporous Materials
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Optimization of Spray-Drying Process of Jerusalem artichoke Extract for Inulin Production

2019

Jerusalem artichoke is an important natural matrix for inulin production. In this experiment, response surface methodology (RSM) was employed to optimize the spray-drying parameters in order to determine the maximal inulin yield. For this study, three independent variables (heating temperature (T&ordf

Materials scienceYield (engineering)<i>Jerusalem artichoke</i>030309 nutrition & dieteticsInulinPharmaceutical ScienceAnalytical Chemistryresponse surface methodologylcsh:QD241-44103 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologylcsh:Organic chemistryDrug DiscoveryResponse surface methodologyFood sciencespray-dryingPhysical and Theoretical ChemistryWater content0303 health sciencesinulinOrganic Chemistry04 agricultural and veterinary sciences040401 food scienceCreepchemistryChemistry (miscellaneous)Spray dryingMolecular MedicineParticle sizeJerusalem artichokeMolecules
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Evaluation of drug-polymer solubility curves through formal statistical analysis: comparison of preparation techniques.

2014

ABSTRACT: In this study, the influence of the preparation technique (ball milling, spray drying, and film casting) of a supersaturated amorphous dispersion on the quality of solubility determinations of indomethacin in polyvinylpyrrolidone was investigated by means of statistical analysis. After annealing of the amorphous dispersions above the crystallization temperature for 2 h, the solubility curve was derived from the glass transition temperature of the demixed material using the Gordon–Taylor relationship and fitting with the Flory–Huggins model. The study showed that the predicted solubility from the ball-milled mixtures was not consistent with those from spray drying and film casting,…

Models MolecularMaterials scienceHot TemperatureChemistry PharmaceuticalDrug CompoundingIndomethacinAnalytical chemistryPharmaceutical SciencemedicinePharmaceutic AidsSolubilitySupersaturationReproducibilityPolyvinylpyrrolidoneCalorimetry Differential ScanningAnti-Inflammatory Agents Non-SteroidalPovidoneReproducibility of ResultsCastingAmorphous solidChemical engineeringSolubilitySpray dryingEmulsionsGlass transitionPowder Diffractionmedicine.drugJournal of pharmaceutical sciences
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