Search results for "spray"

Measurement of pollution levels of N-nitroso compounds of health concern in water using ultra-performance liquid chromatography–tandem mass spectrome…

2017

International audience; This paper reports the development of a highly sensitive analytical method combining solid-phase extraction (SPE) with ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC–MS/MS), for the monitoring of ultra-trace levels of N-nitrosamines in water samples. Under optimized analytical conditions, chromatographic separation was performed in 3 min, in isocratic mode, using an Acquity UHPLC C18 column and a mobile phase consisting of acetonitrile, water, and formic acid (60:40:0.1, v/v/v) at a flow rate of 0.4 mL min−1. Electrospray ionization tandem interface was employed prior to mass spectrometric detection. Good linearity (R2 ≥ 0.9…

Norm values for eosinophil cationic protein in nasal secretions: influence of specimen collection

1999

Background Eosinophil granulocytes play an important role in allergic inflammation of the nasal mucosa. Eosinophil cationic protein (ECP) is a specific eosinophil granule protein released upon activation of these cells. ECP concentration in nasal secretions has been demonstrated to be a good marker for the activity of eosinophilic nasal mucosal inflammation. The clinical use of such a marker requires defined values which are regarded as pathological or within normal range. In analyses of nasal secretion samples, the sampling method has an important influence on the data obtained. Objective We investigated ECP levels in nasal secretions (NS) of healthy volunteers obtained by seven different …

Comparison of the effects of fluticasone propionate, aqueous nasal spray and levocabastine on inflammatory cells in nasal lavage and clinical activit…

1999

BACKGROUND Treatment options for allergic rhinitis include antihistamines, decongestants, anticholinergics, cromolyn sodium and corticosteroids. As the nose is a small organ, comprising less than 1% of total body mass and surface area, it seems logical to confine treatment of rhinitis to the diseased organ. OBJECTIVE To evaluate the effects of therapy with intranasal fluticasone propionate (FP), both on subjective symptoms and pathophysiological mechanisms, in rhinitis patients during pollen season when the patients were symptomatic. METHODS We used a double-blind, placebo (PLA)-controlled, randomized, double dummy, parallel group study of the effect of 6 weeks treatment. The double-blind c…

[N⋅⋅⋅I+⋅⋅⋅N] Halogen-Bonded Dimeric Capsules from Tetrakis(3-pyridyl)ethylene Cavitands

2016

Two [N⋅⋅⋅I+⋅⋅⋅N] halogen-bonded dimeric capsules using tetrakis(3-pyridyl)ethylene cavitands with different lower rim alkyl chains are synthesized and analyzed in solution and the gas phase. These first examples of symmetrical dimeric capsules making use of the iodonium ion (I+) as the main connecting module are characterized by 1H NMR spectroscopy, diffusion ordered NMR spectroscopy (DOSY), electrospray ionization mass spectrometry (ESI-MS), and ion mobility-mass spectrometry (TW-IMS) experiments. The synthesis and effective halogen-bonded dimerization proceeds through analogous dimeric capsules with [N⋅⋅⋅Ag+⋅⋅⋅N] binding motifs as the intermediates as evidenced by the X-ray structures of …

One-step large-scale deposition of salt-free DNA origami nanostructures

2015

AbstractDNA origami nanostructures have tremendous potential to serve as versatile platforms in self-assembly -based nanofabrication and in highly parallel nanoscale patterning. However, uniform deposition and reliable anchoring of DNA nanostructures often requires specific conditions, such as pre-treatment of the chosen substrate or a fine-tuned salt concentration for the deposition buffer. In addition, currently available deposition techniques are suitable merely for small scales. In this article, we exploit a spray-coating technique in order to resolve the aforementioned issues in the deposition of different 2D and 3D DNA origami nanostructures. We show that purified DNA origamis can be …

Pharmacotherapy for Breakthrough Cancer Pain

2012

Breakthrough pain (BTP) is a transient exacerbation of pain that occurs either spontaneously, or in relation to a specific predictable or unpredictable trigger, despite relatively stable and adequately controlled background pain. The principal pharmacological treatment of BTP is represented by the administration of opioids as needed. Oral opioids have traditionally been the only available drugs for BTP. However, the onset and duration of action of oral opioids such as morphine or oxycodone may not be suitable for treating many episodes of BTP that are of short onset and duration. Transmucosal administration of lipophilic substances has gained a growing popularity in recent years due to the …

Development of Antioxidant Protein Extracts from Gilthead Sea Bream (Sparus aurata) Side Streams Assisted by Pressurized Liquid Extraction (PLE)

2021

The pressurized liquid extraction (PLE) technique was used, for the first time, to obtain protein extracts with antioxidant activity from side streams (muscle, heads, viscera, skin, and tailfins) of gilthead sea bream (Sparus aurata) in order to give added value to these underutilized matrices. Extraction conditions previously optimized for sea bass (Dicentrarchus labrax) side streams were applied. Protein recovery percentages were 22% (muscle), 33% (heads), 78% (viscera), 24% (skin), and 26% (tailfins), which represented an increase of 1.2–4.5-fold compared to control samples (extraction by stirring). The SDS-PAGE profiles revealed that PLE-assisted extraction influenced protein molecular …

The water-soluble fraction of marine aerosol particles measured on the Island of Helgoland, North Sea

1997

Investigation of the Cooling of Hot Walls by Liquid Water Sprays

1999

An experimental study was conducted for the heat transfer from hot walls to liquid water sprays. Four full cone, swirl spray nozzles were used at different upstream pressures, giving mass fluxes impinging on the wall, G, from 8 to 80 kg m(-2) s(-1), mean droplet velocities, U, from 13 to 28 m s(-1) and mean droplet diameters, D, from 0.4 to 2.2 mm. A target consisting of two slabs of beryllium-copper alloy, each 4 x 5 cm in size and 1.1 mm thick, was electrically heated to about 300 degrees C and then rapidly and symmetrically cooled by water sprays issuing from two identical nozzles. The midplane temperature was measured by a fast response, thin-foil thermocouple and the experimental data …

The Nukiyama Curve in Water Spray Cooling: its Derivation from Temperature-Time Histories and its Dependence on the Quantities that Characterize Drop…

2007

Abstract Heat transfer from hot aluminium walls to cold water sprays was investigated. The method used was the transient two-side symmetric cooling of a planar aluminium target, previously heated to temperatures of up to 750 K, by twin sprays issuing from full-cone swirl spray nozzles of various gauge. The target’s mid-plane temperature was recorded during the cooling transient by thin-foil K thermocouples and a high-frequency data acquisition system. In order to determine the wall temperature Tw, the wall heat flux q w ″ and the q w ″ - T w heat transfer (Nukiyama) curve, two different approaches were used: the first was based on the solution of an inverse heat conduction problem, the seco…