Search results for "statistica"

showing 10 items of 5969 documents

Purchase intention and purchase behavior online: A cross-cultural approach

2020

This article aims to explore the key factors on e-commerce adoption from elements of social psychology, such as attitude, subjective norms, perceived behavioral control, ease of use and perceived usefulness, introducing the study of non-traditional elements like buying impulse, compatibility, and self-efficacy in online stores, contrasting relationships in a cross-cultural environment. The proposed model is tested from quantitative research with a sample of 584 online consumers in Colombia and Spain. The following statistical analyses were conducted: CFA, structural equations, measurement instrument invariance, and multi-group analysis with EQS 6.3 software. The study reveals that self-effi…

0301 basic medicineTechnology managementOnline purchase intentionColombiaDecision analysisArticlePurchase behavior03 medical and health sciencesCross-cultural psychology0302 clinical medicineStatistical analysesBusinessCross-cultural studylcsh:Social sciences (General)Marketinglcsh:Science (General)Practical implicationsMarketingMultidisciplinarybusiness.industryNational cultureUsabilityConsumer attitudeTechnology management030104 developmental biologyKey factorsSpainlcsh:H1-99businessPsychology030217 neurology & neurosurgerylcsh:Q1-390Technology adoptionDecision analysisHeliyon
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Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy

2017

Fasting reduces glucose levels and protects mice against chemotoxicity, yet drugs that promote hyperglycemia are widely used in cancer treatment. Here, we show that dexamethasone (Dexa) and rapamycin (Rapa), commonly administered to cancer patients, elevate glucose and sensitize cardiomyocytes and mice to the cancer drug doxorubicin (DXR). Such toxicity can be reversed by reducing circulating glucose levels by fasting or insulin. Furthermore, glucose injections alone reversed the fasting-dependent protection against DXR in mice, indicating that elevated glucose mediates, at least in part, the sensitizing effects of rapamycin and dexamethasone. In yeast, glucose activates protein kinase A (P…

0301 basic medicineTime FactorsImmunology and Microbiology (all)Peptide Hormonesmedicine.medical_treatmentAMP-Activated Protein KinasesToxicologyPathology and Laboratory MedicineBiochemistryDexamethasoneMiceEndocrinologyAMP-activated protein kinaseAtrial natriuretic peptideNatriuretic Peptide BrainMedicine and Health SciencesNatriuretic peptideInsulinSmall interfering RNAsBiology (General)Statistical DatabiologyOrganic CompoundsGeneral NeuroscienceMonosaccharidesHeartFastingMetformin3. Good healthMetforminNucleic acidsChemistryPhysical SciencesFemaleAnatomyGeneral Agricultural and Biological SciencesStatistics (Mathematics)Atrial Natriuretic FactorResearch Articlemedicine.drugmedicine.medical_specialtyQH301-705.5medicine.drug_classCarbohydratesEGR1Antineoplastic AgentsCardiotoxinsGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesNatriuretic PeptideStress PhysiologicalInternal medicineGeneticsmedicineAnimalsNon-coding RNAProtein kinase AEarly Growth Response Protein 1Diabetic EndocrinologyNeuroscience (all)Biochemistry Genetics and Molecular Biology (all)Biology and life sciencesToxicityGeneral Immunology and MicrobiologyInsulinOrganic ChemistryChemical CompoundsCorrectionAMPKCyclic AMP-Dependent Protein KinasesHormonesGene regulationDietAtrial Natriuretic PeptideMice Inbred C57BLNeuroscience (all); Immunology and Microbiology (all); Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)Glucose030104 developmental biologyEndocrinologyAgricultural and Biological Sciences (all)CytoprotectionMetabolic DisordersHyperglycemiaCardiovascular Anatomybiology.proteinRNAGene expressionMathematicsPLOS Biology
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Evaluation of Immunofluorescence Antibody Test Used for the Diagnosis of Canine Leishmaniasis in the Mediterranean Basin: A Systematic Review and Met…

2015

With an expected sensitivity (Se) of 96% and specificity (Sp) of 98%, the immunofluorescence antibody test (IFAT) is frequently used as a reference test to validate new diagnostic methods and estimate the canine leihmaniasis (CanL) true prevalence in the Mediterranean basin. To review the diagnostic accuracy of IFAT to diagnose CanL in this area with reference to its Se and Sp and elucidate the potential causes of their variations, a systematic review was conducted (31 studies for the 26-year period). Three IFAT validation methods stood out: the classical contingency table method, methods based on statistical models and those based on experimental studies. A variation in the IFAT Se and Sp …

0301 basic medicineVeterinary medicinelcsh:MedicineArtificial Gene Amplification and ExtensionPolymerase Chain ReactionMediterranean BasinMathematical and Statistical Techniques0302 clinical medicineZoonosesMedicine and Health SciencesCanine leishmaniasisDog Diseaseslcsh:ScienceLeishmaniasisMammalsMultidisciplinaryGeographymedicine.diagnostic_testMediterranean RegionGeographical regionsRegional geographyResearch AssessmentInfectious DiseasesFluorescent Antibody Technique DirectMeta-analysisVertebratesPhysical Sciencesmedicine.symptomStatistics (Mathematics)Research ArticleNeglected Tropical DiseasesSystematic Reviews030231 tropical medicine030106 microbiologyResearch and Analysis MethodsImmunofluorescenceSensitivity and SpecificityAsymptomatic03 medical and health sciencesDogsparasitic diseasesParasitic DiseasesmedicineAnimalsStatistical MethodsMolecular Biology TechniquesMolecular BiologyProtozoan Infectionsbusiness.industrylcsh:RfungiOrganismsReproducibility of ResultsBiology and Life SciencesLeishmaniasisGold standard (test)Tropical Diseasesmedicine.diseaseEarth sciencesParasitologyAmniotesImmunologyMediterranean BasinParasitologylcsh:QbusinessMathematicsMeta-AnalysisPLOS ONE
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Primary vitrectomy for degenerative and tractional lamellar macular holes: A systematic review and meta-analysis

2021

Purpose To assess the efficacy of vitrectomy in degenerative and tractional lamellar macular holes (LMHs) by meta-analysis of published studies. Methods PubMed, Medline and Embase databases were searched up to May 2020. Included cohorts were divided into three groups: degenerative LMH group, lamellar hole associated epiretinal proliferation (LHEP) group and tractional LMH group. LHEP is likely to be associated with degenerative LMHs, but less commonly could be associated with mixed LMHs. To reduce risk of possible misclassification bias, eyes with LHEP which could not have been precisely classified by the authors, were included into the LHEP group. The primary outcome was to investigate th…

0301 basic medicineVisual acuitygenetic structuresVisionmedicine.medical_treatmentVisual AcuitySocial SciencesVitrectomyDatabase and Informatics MethodsMathematical and Statistical Techniques0302 clinical medicineVitrectomyMedicine and Health SciencesPsychologyMedicineDatabase SearchingMacular holeMultidisciplinaryIncidence (epidemiology)StatisticsQOphthalmic ProceduresRMetaanalysisResearch AssessmentMeta-analysisPhysical SciencesMedicineSensory PerceptionAnatomymedicine.symptomResearch Articlemedicine.medical_specialtySystematic ReviewsScienceSurgical and Invasive Medical ProceduresResearch and Analysis Methods03 medical and health sciencesOcular SystemOphthalmologyHumansStatistical Methodsbusiness.industryPrimary vitrectomyCognitive PsychologyBiology and Life SciencesHumans; Retinal Perforations; Visual Acuity; VitrectomyRetinal Perforationsmedicine.diseaseConfidence intervaleye diseases030104 developmental biology030221 ophthalmology & optometryCognitive ScienceEyesPerceptionVisual gainbusinessHeadMathematicsNeuroscience
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Relationship between adipic acid concentration and the core symptoms of autism spectrum disorders.

2016

Dicarboxylic acids are an important source of information about metabolism and potential physiopathological alterations in children with autism spectrum disorders (ASDs). We measured the concentration between dicarboxylic adipic and suberic acids in children with an ASD and typically-developing (TD) children and analyzed any relationships between the severity of the core symptoms of ASDs and other clinical features (drugs, supplements, drugs, or diet). The core symptoms of autism were evaluated using the DSM-IV criteria, and adipic acid and suberic acid were measured in urine samples. Overall, no increase in the concentration of adipic acid in children with ASDs compared to TD children, how…

0301 basic medicineVitamin bMalePediatricsmedicine.medical_specialtyAdolescentAutism Spectrum DisorderAdipatesUrinebehavioral disciplines and activitiesSeverity of Illness Index03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicinemental disordersmedicineHumansDicarboxylic AcidsChildBiological PsychiatryAdipic acidbusiness.industrySignificant differenceMetabolismmedicine.diseaseDiagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental health030104 developmental biologyEndocrinologychemistryCase-Control StudiesChild PreschoolDietary SupplementsVitamin B ComplexAutismFemaleCore symptomsCaprylatesbusinessSuberic acid030217 neurology & neurosurgeryPsychiatry research
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The relationship of mandibular radiomorphometric indices to skeletal age, chronological age and skeletal malocclusion type

2017

Background The present study was performed with the following aims: (1) to assess the relationship between skeletal age, measured using the cervical vertebral maturity (CVM) method, and chronological age; (2) to determine the correlation of skeletal and chronological age to the cortical thickness of the lower border of the mandible using the linear radiomorphometric; and (3) to explore the relationship between these indices and skeletal malocclusion type. Material and methods The data were collected from the records of 180 patients, including 57 males (31.7%) and 123 females (68.3%). The data were based on the panoramic and lateral cephalograms of each patient. The CVM stages were determine…

0301 basic medicinebusiness.industryResearchLateral cephalogramsMandibleDentistryBone ageOrthodonticsChronological age:CIENCIAS MÉDICAS [UNESCO]03 medical and health sciences030104 developmental biologySkeletal malocclusionStatistical significanceUNESCO::CIENCIAS MÉDICASLower borderMedicinebusinessGeneral DentistryJournal of Clinical and Experimental Dentistry
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Molecular Diversity Required for the Formation of Autocatalytic Sets

2019

Systems chemistry deals with the design and study of complex chemical systems. However, such systems are often difficult to investigate experimentally. We provide an example of how theoretical and simulation-based studies can provide useful insights into the properties and dynamics of complex chemical systems, in particular of autocatalytic sets. We investigate the issue of the required molecular diversity for autocatalytic sets to exist in random polymer libraries. Given a fixed probability that an arbitrary polymer catalyzes the formation of other polymers, we calculate this required molecular diversity theoretically for two particular models of chemical reaction systems, and then verify …

0301 basic medicinechemistry.chemical_classificationRandom graphPaleontologyPolymerChemical reactionGeneral Biochemistry Genetics and Molecular BiologyArticleorigin of lifeAutocatalysis03 medical and health sciences030104 developmental biology0302 clinical medicinechemistrySpace and Planetary ScienceAbiogenesisautocatalytic setslcsh:QStatistical physicslcsh:Sciencesystems chemistry030217 neurology & neurosurgeryEcology Evolution Behavior and Systematicsrandom graphsDiversity (business)Life
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How to deal with Haplotype data: An Extension to the Conceptual Schema of the Human Genome

2016

[EN] The goal of this work is to describe the advantages of the application of Conceptual Modeling (CM) in complex domains, such as genomics. Nowadays, the study and comprehension of the human genome is a major challenge due to its high level of complexity. The constant evolution in the genomic domain contributes to the generation of ever larger amounts of new data, which means that if we do not manage it correctly data quality could be compromised (i.e., problems related with heterogeneity and inconsistent data). In this paper, we propose the use of a Conceptual Schema of the Human Genome (CSHG), designed to understand and improve our ontological commitment to the domain and also extend (e…

0301 basic medicinehaplotypesGeISHigher education0206 medical engineeringconceptual modelingLibrary science02 engineering and technologystatistical modelscomputer.software_genreGenomelcsh:QA75.5-76.95Conceptual schema03 medical and health sciencesExtension (metaphysics)Sociologybusiness.industryHaplotypeGeneral MedicineConceptual modelingStatistical models030104 developmental biologyHaplotypesGenetic diagnosisChristian ministryHuman genomelcsh:Electronic computers. Computer scienceData miningbusinessGenetic diagnosiscomputer020602 bioinformaticsgenetic diagnosis.
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Machine learning–XGBoost analysis of language networks to classify patients with epilepsy

2017

Our goal was to apply a statistical approach to allow the identification of atypical language patterns and to differentiate patients with epilepsy from healthy subjects, based on their cerebral activity, as assessed by functional MRI (fMRI). Patients with focal epilepsy show reorganization or plasticity of brain networks involved in cognitive functions, inducing ‘atypical’ (compared to ‘typical’ in healthy people) brain profiles. Moreover, some of these patients suffer from drug-resistant epilepsy, and they undergo surgery to stop seizures. The neurosurgeon should only remove the zone generating seizures and must preserve cognitive functions to avoid deficits. To preserve functions, one sho…

0301 basic medicinemedicine.medical_specialtyCognitive Neuroscience[SCCO.COMP]Cognitive science/Computer scienceAudiologyExtreme Gradient Boostinglcsh:Computer applications to medicine. Medical informaticsArticle03 medical and health sciencesEpilepsy0302 clinical medicineText miningMachine learningmedicineLanguagelcsh:Computer softwareEpilepsyCognitive mapReceiver operating characteristicbusiness.industryCognitionNeurophysiologymedicine.diseaseMLComputer Science ApplicationsStatistical classificationlcsh:QA76.75-76.765030104 developmental biologyNeurologyBinary classification[ SCCO.COMP ] Cognitive science/Computer sciencelcsh:R858-859.7Artificial intelligencePsychologybusiness030217 neurology & neurosurgeryAtypicalXGBoost
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An analysis in vivo of intracanal bacterial load before and after chemo-mechanical preparation: A comparative analysis of two irrigants and two activ…

2016

Background: The goals of this randomized double-blind trial were to assess the antimicrobial activity in vivo of Sodium hypochlorite (NaOCl) vs. chlorhexidine gluconate (CHX) used in combination either with EndoActivator® or IRRI S® files in patients with apical periodontitis. Material and Methods: A total of 120 patients with apical periodontitis (in single or multiple root canals) were randomly assigned to the four irrigation protocols outlined below: Group A: 5.25% sodium hypochlorite (NaOCl) + EndoActivator®; Group B: 5.25% NaOCl + IRRI S® files; Group C: 2% chlorhexidine gluconate (CHX) + EndoActivator®; Group D: 2% CHX + IRRI S® files. Paper points were used to collect microbiological…

0301 basic medicinemedicine.medical_specialtyDentistryOdontologíaEnterococcus faecalisOperative Dentistry and Endodontics03 medical and health scienceschemistry.chemical_compound0302 clinical medicineIn vivomedicineStatistical analysisIn patientGeneral DentistryPeriodontitisbiologybusiness.industryChemo mechanicalResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Antimicrobialmedicine.diseasebiology.organism_classificationCiencias de la saludSurgery030104 developmental biologychemistrySodium hypochloriteUNESCO::CIENCIAS MÉDICASbusinessJournal of Clinical and Experimental Dentistry
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