Search results for "structural model"
showing 8 items of 18 documents
A Structural Deterministic Model for Electrospun Scaffolds.
2009
Assessing pupils' skills : Implications for research in education
2010
10002; The object of this article is the structure and evolution of skills developed by pupils at primary level. Starting from an analysis of the panel data provided by the French Ministry of Education, the main object of this paper is an original measurement of skills using structural models. The findings of this research raise two complementary issues. The first issue concerns the cross-curricular nature of skills suggesting a logic of disciplinary interdependence. The acquisition of a skill may be strongly correlated to the acquisition of other skills belonging to the same subject area or to other subject areas. The notion of a set of skills is used to account for the connections between…
New insights into the pharmacology of the short-chain free fatty acid receptors 2 and 3
2011
Metabolic diseases, such as diabetes, dyslipidemia or obesity, are more and more weighing on public health expenses in developed countries. Despite active research, these widespread diseases remain difficult to handle. Promising new therapeutic strategies against metabolic diseases include the development of drugs targeting the free fatty acid receptors, as key players in metabolism homeostasis. In this context, the current PhD thesis focuses on the study of two G protein-coupled receptors, namely the short-chain free fatty acid receptors 2 (FFA2) and 3 (FFA3). First, we investigated the expression of the two receptors of interest in a variety of cell types. Then, in order to study the phar…
Examining the critical factors that influence the success of construction and demolition waste reverse logistics operations
2022
The reverse logistics (RL) performance of construction and demolition waste (C&DW) differs significantly between countries. Although some countries are successfully circular, other countries are still far behind; with C&DW being largely directed to landfills or being illegally dumped. There is a lack of guidelines on the requirements for transitioning countries towards C&DW diversion, and little attention has been given to the factors that influence the success of C&DW RL and increased circularity. This study aims to develop a framework that helps in structuring and assessing the success of C&DW RL on a regional level and serves as a guide for transitioning developing co…
F-Type Lectins: A highly diversified family of fucose-binding proteins with a unique sequence motif and structural fold, involved in self/non-self-re…
2017
The F-type lectin (FTL) family is one of the most recent to be identified and structurally characterized. Members of the FTL family are characterized by a fucose recognition domain [F-type lectin domain (FTLD)] that displays a novel jellyroll fold (“F-type” fold) and unique carbohydrate- and calcium-binding sequence motifs. This novel lectin family comprises widely distributed proteins exhibiting single, double, or greater multiples of the FTLD, either tandemly arrayed or combined with other structurally and functionally distinct domains, yielding lectin subunits of pleiotropic properties even within a single species. Furthermore, the extraordinary variability of FTL sequences (isoforms) th…
Toward an update of the structural model in Italian submerged areas: contributions from the EMODnet Geology Project
2016
The European Marine Observation and Data Network (EMODNet) Project aims at the collection of as many existing data as possible on European Seas to be represented on digital maps at the 1:250,000 scale, accessible via web through a dedicated portal. It is articulated into different Lots concerning Bathymetry, Geology, Biology, Chemistry, Physics, Physical Habitats, Human activities. The Geology Lot is realized by a Consortium in which the Geological Survey of Italy is partner. EMODnet Geology requires the compilation of a number of layers subdivided into Work Packages (WP), referring to seafloor sediments grainsize, sedimentation rates, Quaternary geology, pre-Quaternary geology and stratigr…
Procedure for Safety Assessment and BIM Modelling of an Historical Complex Structure through a Macroelement Approach: The Building “Molino-Pastificio…
2022
The structural assessment of existing historical structures is a complex task due to the inner main difficulty in making up reliable models for structural analysis, able to include mechanical and geometrical nonlinearities, existing damage, complex configurations and arrangements of materials. This task becomes more difficult in mixed RC-masonry structures, which structural modelling can be particularly tough due to the different connections and interactions between structural members and materials. This paper presents the case study of a multi-storey mixed Reinforced Concrete (RC)- masonry historical structure, namely the former mill “Molino-Pastificio Soresi” building, located in Partinic…
Upside-down ship’s kel-shaped vaults as a contemporary design criteria. The case of the Palace of the Dukes of Braganza in Guimarães (Portugal)
2015
A contemporary worldwide trend is exposing the structural elements of a building to create an articulate and complex architecture whose lines of force give robustness, stability and, at the same time, a sort of lightness and frivolity to the entire construction. However, the combination between the visual conception of architecture and the principles of statics is not new to the world of construction. Exposed structure as a design approach may be observed in many historical buildings, either public, religious or private, and in several cultural and geographical areas where exposed structures communicate power, solidity, and rigour along with an instance of economy and lightness. In this wor…