Search results for "structural"
showing 10 items of 5047 documents
Generation of Natural Runoff Monthly Series at Ungauged Sites Using a Regional Regressive Model
2016
Many hydrologic applications require reliable estimates of runoff in river basins to face the widespread lack of data, both in time and in space. A regional method for the reconstruction of monthly runoff series is here developed and applied to Sicily (Italy). A simple modeling structure is adopted, consisting of a regression-based rainfall–runoff model with four model parameters, calibrated through a two-step procedure. Monthly runoff estimates are based on precipitation, temperature, and exploiting the autocorrelation with runoff at the previous month. Model parameters are assessed by specific regional equations as a function of easily measurable physical and climate basin descriptors. Th…
F-Type Lectins: A highly diversified family of fucose-binding proteins with a unique sequence motif and structural fold, involved in self/non-self-re…
2017
The F-type lectin (FTL) family is one of the most recent to be identified and structurally characterized. Members of the FTL family are characterized by a fucose recognition domain [F-type lectin domain (FTLD)] that displays a novel jellyroll fold (“F-type” fold) and unique carbohydrate- and calcium-binding sequence motifs. This novel lectin family comprises widely distributed proteins exhibiting single, double, or greater multiples of the FTLD, either tandemly arrayed or combined with other structurally and functionally distinct domains, yielding lectin subunits of pleiotropic properties even within a single species. Furthermore, the extraordinary variability of FTL sequences (isoforms) th…
Comparisons of two diaphragm ultrasound-teaching programs: a multicenter randomized controlled educational study
2019
Abstract Background This study aims to ascertain whether (1) an educational program is sufficient to achieve adequate Diaphragm Ultrasound (DUS) assessments on healthy volunteers and (2) combining a video tutorial with a practical session is more effective in making learners capable to obtain accurate DUS measurements, as opposed to sole video tutorial. Results We enrolledstep 1: 172 volunteers naïve to ultrasound. After watching a video tutorial, a questionnaire was administered and considered to be passed when at least 70% of the questions were correctly answered. Course participants who passed the theoretical test were randomized to either intervention or control group. Learners randomiz…
“One Ring to Bind Them All”—Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles
2010
A collection of 26 polyammonium cyclophane-type macrocycles with a large structural diversity has been screened for G-quadruplex recognition. A two-step selection procedure based on the FRET-melting assay was carried out enabling identification of macrocycles of high affinity (ΔT1/2up to30°C) and high selectivity for the human telomeric G-quadruplex. The four selected hits possess sophisticated architectures, more particularly the presence of a pendant side-arm as well as the existence of a particular topological arrangement appear to be strong determinants of quadruplex binding. These compounds are thus likely to create multiple contacts with the target that may be at the origin of their h…
SNPs detection by eBWT positional clustering
2019
Sequencing technologies keep on turning cheaper and faster, thus putting a growing pressure for data structures designed to efficiently store raw data, and possibly perform analysis therein. In this view, there is a growing interest in alignment-free and reference-free variants calling methods that only make use of (suitably indexed) raw reads data. We develop the positional clustering theory that (i) describes how the extended Burrows–Wheeler Transform (eBWT) of a collection of reads tends to cluster together bases that cover the same genome position (ii) predicts the size of such clusters, and (iii) exhibits an elegant and precise LCP array based procedure to locate such clusters in the e…
Natural assets in the right-of-way of A-4 Motorway in the Góra Świętej Anny Landscape Park, Opole Region
2014
Construction of the A-4 Motorway section in the Opole Region begun in Summer 1997. Very soon vigorous resistance of ecological NGOs was encountered. The bone of contention was the section of motorway that passes through the Góra Świętej Anny Landscape Park and verges the natural reserve of strict protection Ligota Dolna where rare species of thermophilic plants are sheltered. Between 2011 and 2013 a detailed mycological, geobotanical, floristic and fauna research took place within the right-of-way of the A-4 Motorway section crossing the Góra Świętej Anny Landscape Park in the Opole Region. The survey revealed several rare and protected species of fungi, plants and animals along the road, i…
The measurement invariance of Job Diagnostic Survey (JDS) across three university student groups
2016
Purpose: The main purpose of this study is to apply a multigroup confirmatory analysis to examine the measurement invariance (MI) of the adapted version of the Job Diagnosis Survey (JDS) as a measurement tool that analyses the relationship between the features of teaching methodologies with university students’ motivation and satisfaction across data collected on different degrees and academic years. Design/methodology/approach: Confirmatory factor analysis was carried out using a multigroup structural equation model, using the program EQS 6.1 to test the invariance of the adapted version of JDS in a sample constituted by 535 student of a Spanish public university. The assessment of invaria…
Optimizing artificial neural networks for the evaluation of asphalt pavement structural performance
2019
Artificial Neural Networks represent useful tools for several engineering issues. Although they were adopted in several pavement-engineering problems for performance evaluation, their application on pavement structural performance evaluation appears to be remarkable. It is conceivable that defining a proper Artificial Neural Network for estimating structural performance in asphalt pavements from measurements performed through quick and economic surveys produces significant savings for road agencies and improves maintenance planning. However, the architecture of such an Artificial Neural Network must be optimised, to improve the final accuracy and provide a reliable technique for enriching d…
Modeling bismuth insertion in 1D hybrid lead halide TMSO(Pb x Bi y )I3 pseudo-perovskites
2022
Abstract The structures of the disordered 1D (pseudo-)perovskites of general TMSO(Pb x Bi y )I3 formulation [TMSO = (CH3)3SO+], obtained by doping the TMSOPbI3 species with Bi3+ ions, are investigated through the formulation of a statistical model of correlated disorder, which addresses the sequences of differently occupied BI6 face-sharing octahedra (B = Pb, Bi or vacant site) within ideally infinite [(BI3)−] n chains. The x-ray diffraction patterns simulated on the basis of the model are matched to the experimental traces, which show many broad peaks with awkward (nearly trapezoidal) shapes, under the assumption that the charge balance is fully accomplished within each chain. The analysis…
Towards a sustainable leader-follower relationship: constructive dissensus, organizational virtuousness and happiness at work (haw)
2020
This paper examines how leaders and followers can interact positively under complex and bounded conditions. For this purpose, this paper conceptualizes and measures the concept of constructive dissensus. Constructive dissensus relates to a mutual understanding leading to a situation of coregulation. In addition, the relationship between constructive dissensus and happiness at work is examined on the basis of affective events theory. Furthermore, the mediating role of organizational virtuousness is assessed. Through structural equation modeling, a multilevel analysis was performed. Data from 130 bank branches and 606 employees were gathered. The results reveal a direct effect of constructive…