Search results for "structures"
showing 10 items of 4815 documents
Stackelberg equilibrium with many leaders and followers. The case of zero fixed costs
2017
Abstract I study a version of the Stackelberg game with many identical firms in which leaders and followers use a continuous cost function with no fixed cost. Using lattice theoretical methods I provide a set of conditions that guarantee that the game has an equilibrium in pure strategies. With convex costs the model shows the same properties as a quasi-competitive Cournot model. The same happens with concave costs, but only when the number of followers is small. When this number is large the leaders preempt entry. I study the comparative statics and the limit behavior of the equilibrium and I show how the main determinants of market structure interact. More competition between the leaders …
PREOPERATIVE ASSESSMENT OF RECTAL CANCER: AN ACCURATE MRI PROTOCOL A RADIOLOGICAL TEMPLATE
2015
Learning objectives Background Findings and procedure details Conclusion Personal information References
Magnetic domain-wall racetrack memory for high density and fast data storage
2012
The racetrack memory device is a new concept of Magnetic RAM (MRAM) based on controlling domain wall (DW) motion in ferromagnetic nanowires. It promises ultra-high storage density thanks to the possibility to store multiple narrow DWS per memory cell. By using read and write heads based on magnetic tunnel junctions (MTJ) with perpendicular magnetic anisotropy (PMA) fast data access speed can also be achieved. Thereby the racetrack memory can be used as universal storage to address both embedded and standalone applications. In this paper, we present the device physics, integration circuit and architecture designs of a racetrack memory based on MTJs with PMA. Mixed SPICE simulations at 65 nm …
Lone Star Stack: Architecture of a Disk-Based Archival System
2014
The need for huge storage systems rises with the ever growing creation of data. With growing capacities and shrinking prices, "write once read sometimes" workloads become more common. New data is constantly added, rarely updated or deleted, and every stored byte might be read at any time - a common pattern for digital archives or big data scenarios. We present the Lone Star Stack, a disk based archival storage system building block that is optimized for high reliability and energy efficiency. It provides a POSIX file system interface that uses flash based storage for write-offloading and metadata and the disk-based Lone Star RAID for user data storage. The RAID attempts to spin down disks a…
LoneStar RAID
2016
The need for huge storage archives rises with the ever growing creation of data. With today’s big data and data analytics applications, some of these huge archives become active in the sense that all stored data can be accessed at any time. Running and evolving these archives is a constant tradeoff between performance, capacity, and price. We present the LoneStar RAID, a disk-based storage architecture, which focuses on high reliability, low energy consumption, and cheap reads. It is designed for MAID systems with up to hundreds of disk drives per server and is optimized for “write once, read sometimes” workloads. We use dedicated data and parity disks, and export the data disks as individu…
A subunit of eukaryotic translation initiation factor 2α-phosphatase (CreP/PPP1R15B) regulates membrane traffic.
2012
The constitutive reverter of eIF2α phosphorylation (CReP)/PPP1r15B targets the catalytic subunit of protein phosphatase 1 (PP1c) to phosphorylated eIF2α (p-eIF2α) to promote its dephosphorylation and translation initiation. Here, we report a novel role and mode of action of CReP. We found that CReP regulates uptake of the pore-forming Staphylococcus aureus α-toxin by epithelial cells. This function was independent of PP1c and translation, although p-eIF2α was involved. The latter accumulated at sites of toxin attack and appeared conjointly with α-toxin in early endosomes. CReP localized to membranes, interacted with phosphomimetic eIF2α, and, upon overexpression, induced and decorated a pop…
Effect of starvation on haemolymph vitellogenins and ovary uptake in Spilostethus pandurus
1993
Abstract 1. 1. Starvation reduces haemolymph vitellogenins and their incorporation by developing oocytes in S. pandurus adult females. 2. 2. Access to food restores unspecifically the protein levels in both haemolymph and ovaries. 3. 3. Topical treatments with JH promote de novo specific synthesis of vitellogenins and incorporation by the ovaries. 4. 4. These results point to a strong role of the JH as the regulatory factor of both reproductive phenomena in S. pandurus .
Sub-threshold signal processing in arrays of non-identical nanostructures
2011
Weak input signals are routinely processed by molecular-scaled biological networks composed of non-identical units that operate correctly in a noisy environment. In order to show that artificial nanostructures can mimic this behavior, we explore theoretically noise-assisted signal processing in arrays of metallic nanoparticles functionalized with organic ligands that act as tunneling junctions connecting the nanoparticle to the external electrodes. The electronic transfer through the nanostructure is based on the Coulomb blockade and tunneling effects. Because of the fabrication uncertainties, these nanostructures are expected to show a high variability in their physical characteristics and…
A study of the human rod and cone electroretinogram a-wave component
2009
The study of the electrical response of the retina to a luminous stimulus is one of the main fields of research in ocular electrophysiology. The features of the first component (a-wave) of the retinal response reflect the functional integrity of the two populations of photoreceptors: rods and cones. We fit the a-wave for pathological subjects with functions that account for possible mechanisms governing the kinetics of the photoreceptors. The paper extends a previous analysis, carried out for normal subjects, in which both populations are active, to patients affected by two particular diseases that reduce the working populations to only one. The pathologies investigated are Achromatopsia, a…
Step-by-Step Control of the Dynamics of a Superconducting QED-like System
2007
We discuss the modus operandi of a theoretical scalable coupling scheme to control step by step the time evolution of a pair of flux qubits embedded in a lossy resonant cavity. The sequential interaction of each qubit with the quantized cavity mode is controlled by externally applied magnetic fluxes. Our analysis indicates that indirect qubit-qubit interactions, with the electromagnetic mode acting as a data bus, can be selectively performed and exploited both for the implementation of entangling gates and for the generation of states with a priori known characteristics.