Search results for "structures"
showing 10 items of 4815 documents
Optomotor-blind negatively regulates Drosophila eye development by blocking Jak/STAT signaling
2015
Organ formation requires a delicate balance of positive and negative regulators. In Drosophila eye development, wingless (wg) is expressed at the lateral margins of the eye disc and serves to block retinal development. The T-box gene optomotor-blind (omb) is expressed in a similar pattern and is regulated by Wg. Omb mediates part of Wg activity in blocking eye development. Omb exerts its function primarily by blocking cell proliferation. These effects occur predominantly in the ventral margin. Our results suggest that the primary effect of Omb is the blocking of Jak/STAT signaling by repressing transcription of upd which encodes the Jak receptor ligand Unpaired.
Cytotoxicity of a new hemostatic agent on human pulp fibroblasts in vitro
2011
Objective: The objective of this study was to evaluate the cytotoxicity of the plant extract ankaferd blood stopper (ABS) in vitro. Study Design: ABS was eluted with fresh Dulbecco's Modified Eagle's Medium (DMEM) without serum for 72 h, at 37°C. The cells treated with various dilutions of ABS were seeded into 96-well microplate at 10 4 /well in triplicates. Cells without treatment served as a control group. The number of viable cells after 48 h incubation was determined by a modified 3-(4, 5-dimethyl-thiazol-2-yl)-2, 5-diphenyl-tetrazolium bromide (MTT) assay. The relative viability of pulp cells was expressed as color intensity of the number in the experimental wells relative to that of t…
Thinking about anxiety moderates the relationship between implicit and explicit anxiety measures
2008
Abstract Explicit measures (e.g., questionnaires) assess introspectively accessible self-descriptions and evaluations. In contrast, implicit measures (e.g., the Implicit Association Test) assess the self-concept indirectly, usually by means of performance measures such as reaction-time tasks. Correlations between implicit and explicit measures of personality dispositions tend to be low. The current study ( N = 82) tested the hypothesis that thinking about anxiety-arousing (vs. extraversion-arousing) situations moderates the relationship between implicit and explicit anxiety measures. Results supported this prediction: While no association between implicit and explicit anxiety measures was …
General support versus individual work support: a qualitative study of social workers and therapists in collaboration meetings within individual plac…
2020
This study aims to increase understanding of how social workers and therapists contribute to cooperation meetings within the individual placement and support intervention. The individual placement and support model of supported employment is expanding worldwide. Although several quantitative studies have shown this model`s effect, the need for qualitative studies on collaboration within this intervention is evident. The individual placement and support fidelity manual presents clear expectations to the social workers and therapist in the cooperation. Still, few previous studies investigate how these expectations are met in praxis. This study draws on sixteen collaboration meetings, recorded…
Polyamines and ripening of photoreceptor outer segments in chicken embryos.
1995
Abstract Polyamines and their related monoacetyl derivatives were studied in rod outer segment (ROS) and cone outer segment (COS) of photoreceptor cells from chick embryo retina during eye development (7th–18th days). Putrescine was found to be necessary, in the second phase of retinogenesis, to sustain both ROS and COS differentiation and, after acetylation, γ-aminobutyric acid synthesis. On the other hand, spermidine and even more spermine intervene in the third phase of development when photoreceptors mature. Moreover, the presence of N1-acetylspermidine already at the 7th day indicates that in the outer segment of photoreceptor cells too, as in the whole retina, putrescine synthesis com…
Communication between iron(II) building blocks in cooperative spin transition phenomena
2003
[EN] In the present article we discuss the cooperative nature of the spin crossover phenomenon in iron(II) complexes, providing a perspective of the state of the art in this area. The first aspect we discuss is the role of the intermolecular interactions, more precisely the ¿-interactions, in mononuclear complexes. We show that by playing with the nature of the ligands, aliphatic, aromatic, or extended aromatic, it is possible to create stronger cohesive forces and receive a more cooperative response from the compound. In the next step the singular family of bipyrimidine-bridged iron(II) dinuclear compounds is presented as the simplest example of polynuclear spin crossover complexes exhibit…
Optical and electrical properties of oriented thin films of oligomer containing betaine-type moiety in side chain
2005
Non-linear optical and electrical properties of polymer films obtained by dipole orientation of active units are reported. Novel polar oligomer with N-(indan-1,3-dion-2-yl)pyridinium betaine (IPB) as a side group is studied. Orientation of polar groups in oligomer thin films causes an increase of the photo-induced change of surface potential on irradiation in the region of photo-induced electron transfer (PIET) where the IPB group exhibits a reversible change of the value and sign of the dipole moment. At longer wavelengths, the value of the surface potential of the oligomer may be determined by transport of photogenerated charge carriers.
Resonance properties of GABAergic interneurons in immature GAD67-GFP mouse neocortex.
2014
Subthreshold resonance is a characteristic membrane property of different neuronal classes, is critically involved in the generation of network oscillations, and tunes the integration of synaptic inputs to particular frequency ranges. In order to investigate whether neocortical GABAergic interneurons show resonant behavior already during early postnatal development, we performed whole-cell patch-clamp recordings from visually identified interneurons in supragranular layers of parietal regions in coronal neocortical slices from postnatal day (P) P6-P13 GAD67-GFP knock-in mice. Subthreshold resonance was analyzed by injection of sinusoidal current with varying frequency. About 50% of the inve…
Socioecological correlates of perceived motor competence in 5- to 7-year-old Finnish children
2019
We investigated child, family, and environmental factors associated with young children’s perceptions of locomotor (LM) and object control (OC) skills. The participants comprised 472 children (6.22 ± 0.63) and their parents. The children were assessed for their perception of motor competence in LM and OC skills (using the pictorial scale of Perceived Movement Skill Competence for young children), and actual motor competence (Test of Gross Motor Development 3rd edition and Körperkoordinationstest Für Kinder). Anthropometrics were calculated using the children’s body mass index standard deviation scores. A parent questionnaire included questions about child factors (sex, child’s independent w…
Diplostomum spathaceum metacercarial infection and colour change in salmonid fish
2004
Colour changes in two salmonid fish, the salmon (Salmo salar) and sea trout (S. trutta), were examined in relation to infection with the trematode Diplostomum spathaceum. This parasite had no effect on the rate of colour change in these fish, although species specific differences in colour adjustment times were observed. Increasing asymmetry in parasite numbers between the right and left eye, which could lead to the retention of vision in one eye, nevertheless tended to reduce the colour change time in salmon with moderate infection (P=0.08). This first experimental attempt to examine colour changes in fish in relation to eye fluke infections provides grounds for future investigations. The …