Search results for "sun"
showing 10 items of 935 documents
The defendant’s guilt beyond a reasonable doubt in the Italian criminal justice system
2021
The criminal law standard of Beyond A Reasonable Doubt (BARD) constitutes an evidentiary and judicial rule, formulated and applied for centuries in common law jurisdictions, which was expressly stated in the Italian Code of Criminal Procedure only about fifteen years ago. Unfortunately, the concept of reasonable doubt is inherently complex and does not easily lend itself to definition or refinement. In this regard, the Author examines especially the various positions and elaborations developed by legal literature and case-law in Italy, proposing a specific interpretation of the BARD rule that enhances and completes the particular procedural connotations of the adversarial system adopted i…
Sociālās kampaņas "Suns meklē mājas" efektivitātes novērtējums
2015
Bakalaura darba nosaukums ir Sociālās kampaņas “Suns meklē mājas” efektivitātes novērtējums. Pētījuma problēmjautājums - vai sociālā kampaņa ir bijusi efektīva - vai cilvēki pamanīja šo kampaņu, kādas ir viņu emocijas, attieksme un uzvedība. Bakalaura darba teorija sastāv no 4 nodaļām – sociālais mārketings, sociālā reklāma, reklāmas efektivitātes dimensijas un dzīvnieku ētika kā sociālās kampaņas saturs. Empīriskajā daļā tika izmantotas 3 pētniecības metodes – daļēji strukturētā intervija, satura analīze un aptauja. Izstrādājot pētījumu, galvenais secinājums ir tāds, ka kampaņa bija efektīva, cilvēkiem sociālā kampaņa patika, tā izraisīja, galvenokārt pozitīvas emocijas.
1.6 suns at 58°20′N - the solar resource in Southern Norway
2014
We measured an extreme overirradiance event of 1.6 suns at latitude 58°20′N during a solar resource assessment in southern Norway. The burst occurred when the sun showed in a narrow gap between broken, optically thin altocumulus clouds. The enhancement was most intense within 3° around the solar disk. The annual solar irradiation in the plane of an optimally tilted PV array peaked at 1.30 MWh/m2 in the year 2013, and measured 1.20 MWh/m2 in the previous two years. These values exclude irradiance below 0.05 suns but include reflections from the sea surface and terrain which have not been quantified. The long-term average predicted by the Photovoltaic Geographical Information System (PVGIS) i…
The polarimetric and helioseismic imager on solar orbiter
2020
This paper describes the Polarimetric and Helioseismic Imager on the Solar Orbiter mission (SO/PHI), the first magnetograph and helioseismology instrument to observe the Sun from outside the Sun-Earth line. It is the key instrument meant to address the top-level science question: How does the solar dynamo work and drive connections between the Sun and the heliosphere? SO/PHI will also play an important role in answering the other top-level science questions of Solar Orbiter, as well as hosting the potential of a rich return in further science. SO/PHI measures the Zeeman effect and the Doppler shift in the FeI 617.3nm spectral line. To this end, the instrument carries out narrow-band imaging…
Sphinx measurements of the 2009 solar minimum x-ray emission
2012
The SphinX X-ray spectrophotometer on the CORONAS-PHOTON spacecraft measured soft X-ray emission in the 1-15 keV energy range during the deep solar minimum of 2009 with a sensitivity much greater than GOES. Several intervals are identified when the X-ray flux was exceptionally low, and the flux and solar X-ray luminosity are estimated. Spectral fits to the emission at these times give temperatures of 1.7-1.9 MK and emission measures between 4 x 10^47 cm^-3 and 1.1 x 10^48 cm^-3. Comparing SphinX emission with that from the Hinode X-ray Telescope, we deduce that most of the emission is from general coronal structures rather than confined features like bright points. For one of 27 intervals o…
Search for Gamma-Ray Emission from the Sun during Solar Minimum with the ARGO-YBJ Experiment
2019
The hadronic interaction of cosmic rays with solar atmosphere can produce high energy gamma-rays. The gamma-ray luminosity is correlated both with the flux of primary cosmic rays and the intensity of the solar magnetic field. The gamma-rays below 200 GeV have been observed by Fermi without any evident energy cutoff. The bright gamma-ray flux above 100 GeV has been detected only during solar minimum. The only available data in the TeV range come from the HAWC observations, however, outside the solar minimum. The ARGO-YBJ data set has been used to search for sub-TeV/TeV gamma-rays from the Sun during the solar minimum from 2008 to 2010, the same time period covered by the Fermi data. A suitab…
Solar Surface Magnetism and Irradiance on Time Scales from Days to the 11-Year Cycle
2009
The uninterrupted measurement of the total solar irradiance during the last three solar cycles and an increasing amount of solar spectral irradiance measurements as well as solar imaging observations (magnetograms and photometric data) have stimulated the development of models attributing irradiance variations to solar surface magnetism. Here we review the current status of solar irradiance measurements and modelling efforts based on solar photospheric magnetic fields. Thereby we restrict ourselves to the study of solar variations from days to the solar cycle. Phenomenological models of the solar atmosphere in combination with imaging observations of solar electromagnetic radiation and meas…
Sunitinib in patients with advanced hepatocellular carcinoma after progression under sorafenib treatment.
2010
<i>Objective:</i> To evaluate the safety and efficacy of sunitinib in patients with advanced hepatocellular carcinoma (HCC) after progression under sorafenib treatment. <i>Methods:</i> Sunitinib was administered at 37.5 mg daily (4-weeks-on/2-weeks-off schedule) after progression under sorafenib treatment. Adverse events (AEs) were assessed using NCI-CTCAE v3.0, and tumor response was evaluated according to RECIST. Data were analyzed retrospectively. <i>Results:</i> Eleven patients with metastatic disease were treated. Seven patients (64%) presented with no liver cirrhosis, including 3 patients with a history of liver transplantation. The first radiologic…
Cardiovascular Damage Induced by Anti-VEGF Therapy
2018
Vascular endothelial growth factor (VEGF) plays an important role in maintaining the regular homeostasis of vascular walls. VEGF binds its receptor (VEGFR) promoting the regular survival and function of endothelial cells. Anti-VEGF and anti-VEGFR drugs inhibit the action of VEGF and VEGFR. These drugs can cause cardiovascular toxic effects such as arterial hypertension, thromboembolism, myocardial ischemia and heart failure. The monoclonal antibody bevacizumab and tyrosine kinase inhibitors (sorafenib, sunitinib, pazopanib, regorafenib, axitinib, cabozantinib, ponatinib) are the main inhibitors of VEGF, VEGFR and other tyrosine kinases. In this chapter we will illustrate the cardiovascular …
BIBF 1120/ nintedanib : a new triple angiokinase inhibitor-directed therapy in patients with non-small cell lung cancer.
2013
Abstract: Introduction: Several new targeted agents with anti-angiogenic properties have been developed recently, including vandetanib, sunitinib, sorafenib, bevacizumab and others. Tumor development, progression, metastasis are strongly linked to angiogenesis. Targeted agents like bevacizumab, a monoclonal antibody which targets VEGF, have been fully developed in several solid tumors. These new agents strongly advocate that targeting angiogenesis is one of the best approaches for cancer therapy. Areas covered: Those agents that target additional pro-angiogenic intracellular signaling pathways beyond VEGF signaling have also the potential to contribute to anticancer therapies. The authors p…