Search results for "supramolecular"

showing 10 items of 830 documents

Tuning the pH-Switch of Supramolecular Polymer Carriers for siRNA to Physiologically Relevant pH

2017

The preparation of histidine enriched dendritic peptide amphiphiles and their self-assembly into multicomponent pH-switchable supramolecular polymers is reported. Alternating histidine and phenylalanine peptide synthons allow the assembly/disassembly to be adjusted in a physiologically relevant range of pH 5.3-6.0. Coassembly of monomers equipped with dendritic tetraethylene glycol chains with monomers bearing peripheral primary amine groups leads to nanorods with a tunable cationic surface charge density. These surface functional supramolecular polycations are able to reversibly bind short interfering RNA (siRNA). The nanorod-like supramolecular polymers, their complexation with siRNA, and…

DendrimersCircular dichroismPolymers and PlasticsStereochemistryPhenylalanineStatic ElectricitySupramolecular chemistryBioengineeringPeptide02 engineering and technology010402 general chemistry01 natural sciencesPolyethylene GlycolsBiomaterialschemistry.chemical_compoundCationsAmphiphileMaterials ChemistryHistidineRNA Small Interferingchemistry.chemical_classificationDrug CarriersNanotubesGene Transfer Techniquestechnology industry and agricultureCationic polymerizationHydrogen-Ion Concentration021001 nanoscience & nanotechnologyCombinatorial chemistry0104 chemical sciencesSupramolecular polymersMonomerchemistrySelf-assemblyPeptides0210 nano-technologyBiotechnology
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Synthesis of quadruped-shaped polyfunctionalized o-carborane synthons

2011

[EN] o-Carborane derivatives with precisely defined patterns of substitution have been prepared from 8,9,10,12-I-4-1,2-closo-C2B10H8 by replacing the iodine atoms, bonded to four adjacent boron vertices in the cluster, with allyl, and subsequently 3-hydroxypropyl groups. The resulting structures, comprising four pendant arms and two reactive vertices located on opposite sides of a central o-carborane core, can be envisaged as versatile precursors for dendritic growth

DendrimersIcosahedral CarboranesStereochemistryMolecular ConformationNeutron-Capture TherapySupramolecular Assemblieschemistry.chemical_elementBoranesCrystallography X-Ray010402 general chemistry01 natural sciencesCatalysisMolecular conformationDendrimerQUIMICA ANALITICAMaterials ChemistryCluster (physics)BoranesBoronta116CancerIodination010405 organic chemistryChemistryPolysubstituted FrameworksSynthonMetals and AlloysHalogenationGeneral Chemistry3. Good health0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsC-HChemistryCrystallographyCeramics and CompositesCarboraneDerivativesIodineChemical Communications
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Molecular and supramolecular structures of self-assembled Cu(II) and Co(II) complexes with 4,4’-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-1,3,5-triazine-2,4-…

2020

Abstract The molecular and supramolecular structures of [Cu(PTM)Cl2]∗0.75MeOH (1), [Co(PTM)Cl2]; (2A) and [Co(PTM)Cl2(EtOH)]; (2B) complexes, where PTM is 4,4’-[6-(3,5-dimethyl-1H-pyrazol-1-yl)-1,3,5-triazine-2,4-diyl]dimorpholine, were presented. In complexes 1 and 2A, the Cu(II) and Co(II) are tetra-coordinated with a distorted tetrahedral coordination environment. In case of complex 2B, an additional ethanol molecule is found coordinated with Co(II) leading to a highly distorted penta-coordinated Co(II) complex. In all cases, the PTM ligand is acting as a bidentate NN-chelate. Hirshfeld surface analysis indicated the importance of H⋯H (49.0–55.1%), Cl⋯H (18.8–20.5%) and O⋯H (8.3–9.9%) co…

Denticity010405 organic chemistryLigandChemistryOrganic ChemistryAtoms in moleculesSupramolecular chemistry010402 general chemistry01 natural sciences0104 chemical sciencesAnalytical ChemistryInorganic ChemistryCrystallographyCovalent bondMoleculeOpen shellSpectroscopyNatural bond orbitalJournal of Molecular Structure
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Template-controlled assembly of ditopic catechol phosphines: a strategy for the generation of complexes of bidentate phosphines with different bite a…

2008

A rational approach to the synthesis of heterobi- or -trimetallic complexes based upon self-assembly of a flexible ditopic catechol-phosphine ligand with [(cod)PdCl(2)] and simple metal halides such as GaCl(3), BiCl(3), SnCl(4), or ZrCl(4) is described. All products were characterized by spectroscopic and analytical data and single-crystal X-ray diffraction studies. The molecular structures can be described in terms of cis-configured palladium complexes with supramolecular bisphosphine ligands that are formed by the assembly of two phosphine catecholate fragments on a main group/transition metal template. Of particular interest are the distinct decreases in P-Pd-P bite angles and P...P dist…

Denticity010405 organic chemistryStereochemistryLigandOrganic ChemistrySupramolecular chemistrychemistry.chemical_elementGeneral Chemistry010402 general chemistry01 natural sciencesCatalysis0104 chemical scienceschemistry.chemical_compoundCrystallographyMetal halideschemistryTransition metalCovalent radiusPhosphinePalladiumChemistry (Weinheim an der Bergstrasse, Germany)
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Heteropolymetallic Supramolecular Solid-State Architectures Constructed from [Cr(AA)(C2O4)2]- Tectons, and Sustained by Coordinative, Hydrogen Bond a…

2004

The paper reports on four novel solid-state architectures constructed by using tectons having the general formula:  [Cr(AA)(C2O4)2]- [AA = 2,2‘-bipyridine (bipy) and 1,10-phenanthroline (phen)]. These building blocks are involved in various intermolecular interactions:  coordinative, hydrogen bonds, and π−π contacts. Two new crystallohydrates in the Ba[Cr(AA)(C2O4)2]2·nH2O family have been characterized:  [BaCr2(bipy)2(C2O4)4(H2O)2]·4H2O (1) and [BaCr2(phen)2(C2O4)4(H2O)2] (2). Because of the different numbers of water molecules, their crystal structures are completely different from those of two others previously reported, [BaCr2(bipy)2(C2O4)4(H2O)]·H2O and [BaCr2(phen)2(C2O4)4(H2O)2]·4H2O…

DenticityChemistryHydrogen bondPhenanthrolineStackingSupramolecular chemistryGeneral ChemistryCrystal structureCondensed Matter Physics22'-Bipyridinechemistry.chemical_compoundCrystallographyMoleculeGeneral Materials ScienceCrystal Growth & Design
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Cu(II) and Cu(I) complexes with 1,2-dithiosquarate as a ligand; from molecular compounds to supramolecular network structures

2008

Abstract Four new complexes of copper(II) and/or copper(I) with 1,2-dtsq as a ligand have been synthesized and characterized by single crystal X-ray diffraction methods, [CuII(terpy)(1,2-dtsq)] (1), [CuII(dmen)(1,2-dtsq)]n (2), {[CuII(dmen)2][CuI(1,2-dtsq)]2}n·2nH2O(3) and {[CuII(men)2][CuI (1,2-dtsq)]2}n·nH2O (4) (1,2-dtsq = 1,2-dithiosquarate, dianion of 3,4-dimercapto-1-cyclobutene-1,2-dione; dmen = N,N-dimethylethylenediamine; men = N-methylethylenediamine, terpy = 2,2′:6,2″-terpyridine). Compound 1 consists of neutral [CuII(terpy)(1,2-dtsq)] mononuclear units which are held together by O⋯H–C and van der Waals interactions. Compound 2 is built of neutral [CuII(dmen)(1,2-dtsq)] entities …

DenticityCoordination sphereChemistryLigandOrganic ChemistrySupramolecular chemistrychemistry.chemical_elementCrystal structureCopperAnalytical ChemistryInorganic Chemistrysymbols.namesakeCrystallographysymbolsvan der Waals forceSingle crystalSpectroscopyJournal of Molecular Structure
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Manganese(II) complexes with croconate and 2-(2-pyridyl)imidazole ligands: Syntheses, X-ray structures and magnetic properties

2009

Abstract The mixed-ligand complexes of manganese(II) of formula [Mn(pyim)2(C5O5)] (1) and [Mn(pyim)(H2O)(C5O5)]n · 2.5nH2O (2) [pyim = 2-(2-pyridyl)imidazole and C 5 O 5 2 -  = croconate (dianion of 4,5-dihydroxy-4-cyclopentene-1,2,3-trione)] have been prepared and their structures determined by X-ray crystallographic methods. Compound 1 is a tris-chelated mononuclear complex where the manganese atom is six-coordinate: four nitrogen atoms from two pyim molecules and two oxygen atoms from a croconate group build a somewhat distorted octahedral surrounding around the metal atom. The resulting neutral mononuclear units are linked to each other through double bridges which are constituted by th…

DenticityLigandInorganic chemistrySupramolecular chemistrychemistry.chemical_elementCrystal structureManganeseInorganic Chemistrychemistry.chemical_compoundCrystallographychemistryOctahedronMaterials ChemistryMoleculeImidazolePhysical and Theoretical ChemistryInorganica Chimica Acta
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Study of the complex formation between the [Cu(bpca)]+ secondary building unit and the aromatic N donors 2,3,5,6-tetra(2-pyridyl)pyrazine (tppz) and …

2017

Two new complexes of the formula [{Cu(bpca)}2(μ-tppz)](NO3)2·5H2O (1) and [Cu(bpca)(H2O)(ClO4)(μ-bpp)Cu(bpca)(H2O)2]ClO4·H2O (2) [tppz = 2,3,5,6-tetra(2-pyridyl)pyrazine and bpp = 1,3-bis(4-pyridyl)propane] have been prepared by the reaction of the [Cu(bpca)]+ [Hbpca = bis(2-pyridylcarbonyl)imide] building block and the tppz and bpp N donors. An unusual coordination mode of the tppz ligand was observed in 1, which functions as a bis(bidentate) ligand to two copper(II) atoms each coordinated to a nitrogen atom of the pyrazine moiety and a pyridyl nitrogen atom. This compound presents a layered structure of alternating anionic (ca. 1.6 A) and cationic (ca. 10 A) slices, providing the opportun…

DenticityPyrazine010405 organic chemistryInorganic chemistrySupramolecular chemistryGeneral Chemistry010402 general chemistryCondensed Matter Physics01 natural sciences0104 chemical scienceschemistry.chemical_compoundPerchlorateCrystallographychemistryElectronic effectMoleculeMoietyGeneral Materials ScienceImideCrystEngComm
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Hydrogen and Halogen Bond Mediated Coordination Polymers of Chloro-Substituted Pyrazin-2-Amine Copper(I) Bromide Complexes

2020

A new class of six mono- (1

DenticityPyrazineDimer116 Chemical sciencesSubstituentSupramolecular chemistry010402 general chemistry01 natural scienceskemialliset sidoksetchemistry.chemical_compoundcopper halidehydrogen bondvetysidoksetHalogen bondhalogeenit010405 organic chemistryHydrogen bondCopper(I) bromideGeneral Medicine3. Good health0104 chemical sciencesCrystallographychemistryhalogeenisidoksetchloropyrazinechloropyrazin-2-aminepyrazinehalogen bondChemistry
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Bio-metal-organic frameworks for molecular recognition and sorbent extraction of hydrophilic vitamins followed by their determination using HPLC-UV

2020

A bio-metal-organic framework (bio-MOF) derived from the amino acid L-serine has been prepared in bulk form and evaluated as sorbent for the molecular recognition and extraction of B-vitamins. The functional pores of bio-MOF exhibit high amounts of hydroxyl groups jointly directing other supramolecular host-guest interactions thus providing the recognition of B-vitamins in fruit juices and energy drinks. Single-crystal X-ray diffraction studies reveal the specific B-vitamin binding sites and the existence of multiple hydrogen bonds between these target molecules and the framework. It offered unique snapshots to accomplish an efficient capture of these solutes in complex aqueous matrices. Fo…

Detection limitVitaminesSorbentChromatographySurface PropertiesUltraviolet RaysElutionChemistryHydrophilic interaction chromatography010401 analytical chemistryExtraction (chemistry)Supramolecular chemistryQuímica analítica010402 general chemistry01 natural sciences0104 chemical sciencesAnalytical ChemistryBegudesMolecular recognitionVitamin B ComplexAdsorptionSolid phase extractionParticle SizeHydrophobic and Hydrophilic InteractionsMetal-Organic FrameworksMicrochimica Acta
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