Search results for "surface plasmon"

showing 10 items of 393 documents

A compound-based proteomic approach discloses 15-ketoatractyligenin methyl ester as a new PPARγ partial agonist with anti-proliferative ability

2017

AbstractProteomics based approaches are emerging as useful tools to identify the targets of bioactive compounds and elucidate their molecular mechanisms of action. Here, we applied a chemical proteomic strategy to identify the peroxisome proliferator-activated receptor γ (PPARγ) as a molecular target of the pro-apoptotic agent 15-ketoatractyligenin methyl ester (compound 1). We demonstrated that compound 1 interacts with PPARγ, forms a covalent bond with the thiol group of C285 and occupies the sub-pocket between helix H3 and the β-sheet of the ligand-binding domain (LBD) of the receptor by Surface Plasmon Resonance (SPR), mass spectrometry-based studies and docking experiments. 1 displayed…

Transcriptional Activation0301 basic medicinenatural productTime FactorsPeroxisome proliferator-activated receptorApoptosisLigandsPartial agonistArticleRosiglitazonePPAR_gammaJurkat Cells03 medical and health sciencesTransactivation0302 clinical medicineproteomicsHumansBinding siteReceptorMode of actionPI3K/AKT/mTOR pathwayCell Proliferationchemistry.chemical_classificationBinding SitesMultidisciplinaryProtein StabilityProtein Proliferator-Activated-Receptor PPARs Ligand-Binding Domain Chemical Proteomics Accurate Docking Pi3k/Akt Pathway Drug Discovery Anticancer compoundsReproducibility of ResultsEstersSurface Plasmon ResonanceMolecular Docking SimulationPPAR gammaKineticsHEK293 Cells030104 developmental biologychemistryBiochemistryDocking (molecular)030220 oncology & carcinogenesisThermodynamicsThiazolidinedionesproteomics PPAR_gamma natural productDiterpenes KauraneHT29 CellsScientific Reports
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Ultrathin high-index metasurfaces for shaping focused beams

2015

The volume size of a converging wave, which plays a relevant role in image resolution, is governed by the wavelength of the radiation and the numerical aperture (NA) of the wavefront. We designed an ultrathin (λ/8 width) curved metasurface that is able to transform a focused field into a high-NA optical architecture, thus boosting the transverse and (mainly) on-axis resolution. The elements of the metasurface are metal-insulator subwavelength gratings exhibiting extreme anisotropy with ultrahigh index of refraction for TM polarization. Our results can be applied to nanolithography and optical microscopy. Spanish Ministry of Economy and Competitiveness (MEC) (TEC2013-50416-EXP).

WavefrontMaterials scienceSubwavelength structuresbusiness.industryMaterials Science (miscellaneous)Surface plasmonPhysics::OpticsSurface plasmonsPolarization (waves)Industrial and Manufacturing EngineeringNumerical apertureWavelengthNanolithographyOpticsBusiness and International ManagementResolutionbusinessImage resolutionRefractive indexÓptica
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Excitation of surface plasmon polaritons guided mode by Rhodamine B molecules doped in PMMA stripe

2010

In this letter we show the inclusion of Rhodamine B molecules (RhB) inside a dielectric-loaded surface plasmon waveguide enables for a precise determination of its optical characteristics. The principle relies on the coupling of the fluorescence emission of the dye to plasmonic waveguided modes allowed in of the structure. Using leakage radiation microscopy in real and reciprocal spaces, we measure the propagation constant of the mode and as well as their attenuation length.

Waveguide (electromagnetism)Guided wave testingMaterials sciencebusiness.industrySurface plasmonPhysics::OpticsFOS: Physical sciencesSurface plasmon polaritonAtomic and Molecular Physics and Opticschemistry.chemical_compoundOpticschemistryMicroscopyRhodamine BOptoelectronicsPropagation constantbusinessPlasmonPhysics - OpticsOptics (physics.optics)
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Leakage radiation microscopy of surface plasmon coupled emission: investigation of gain-assisted propagation in an integrated plasmonic waveguide.

2010

International audience; Using a single-mode dielectric-loaded surface plasmon polariton waveguide doped with quantum dots, we were able to slightly increase the propagation length of the mode by stimulated emission of plasmon. We analyse the amplification phenomenon in the visible range by combining leakage radiation microscopy and surface plasmon coupled emission techniques.

Waveguide (electromagnetism)HistologyMaterials sciencePhysics::OpticsLeakage radiation microscopy02 engineering and technology01 natural sciencesPathology and Forensic MedicineplasmonOptics0103 physical sciencesPhysics::Atomic and Molecular ClustersSpaserStimulated emissionSurface plasmon resonance[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics010306 general physicsPlasmonbusiness.industrysurface plasmon coupled emissionSurface plasmonspaser021001 nanoscience & nanotechnologySurface plasmon polaritonOptoelectronics[ SPI.NANO ] Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics0210 nano-technologybusinessLocalized surface plasmonJournal of microscopy
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Performance of electro-optical plasmonic ring resonators at telecom wavelengths

2012

International audience; In this work we report on the characteristics of an electro-optical dielectric-loaded surface plasmon polariton waveguide ring resonator. By doping the dielectric host matrix with an electro-optical material and designing an appropriate set of planar electrodes, we measured a 16% relative change of transmission upon application of a controlled electric field. We have analyzed the temporal response of the device and conclude that electrostriction of the host matrix is playing a dominating role in the transmission response.

Waveguide (electromagnetism)Materials sciencePhysics::Optics02 engineering and technologyDielectric01 natural sciences010309 opticsCondensed Matter::Materials ScienceResonatorOpticsEXCITATION0103 physical sciencesINTERFEROMETERSMODULATIONPlasmon[PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics][ PHYS.PHYS.PHYS-OPTICS ] Physics [physics]/Physics [physics]/Optics [physics.optics]ElectrostrictionSURFACE-PLASMONbusiness.industrySurface plasmonOptical DevicesEquipment DesignSurface Plasmon Resonance021001 nanoscience & nanotechnologySurface plasmon polaritonAtomic and Molecular Physics and OpticsEquipment Failure AnalysisWAVE-GUIDE COMPONENTSTelecommunicationsOptoelectronicsElectronics0210 nano-technologybusinessFILMLocalized surface plasmonOptics Express
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Efficient excitation of dielectric-loaded surface plasmon-polariton waveguide modes at telecommunication wavelengths

2008

International audience; The excitation of surface plasmon-polariton (SPP) waveguide modes in subwavelength dielectric ridges deposited on a thin gold film has been characterized and optimized at telecommunication wavelengths. The experimental data on the electromagnetic mode structure obtained using scanning near-field optical microscopy have been directly compared to full vectorial three-dimensional finite element method simulations. Two excitation geometries have been investigated where SPPs are excited outside or inside the dielectric tapered region adjoint to the waveguide. The dependence of the efficiency of the SPP guided mode excitation on the taper opening angle has been measured an…

Waveguide (electromagnetism)Materials sciencegenetic structures/dk/atira/pure/subjectarea/asjc/2500/2504NanophotonicsPhysics::Optics02 engineering and technologyDielectric01 natural sciences010309 opticsOptics0103 physical sciencesPolariton[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/MicroelectronicsELECTROMAGNETIC ENERGY-TRANSPORT[PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics]NANO-OPTICS[ PHYS.PHYS.PHYS-OPTICS ] Physics [physics]/Physics [physics]/Optics [physics.optics]business.industry/dk/atira/pure/subjectarea/asjc/3100/3104COMPONENTSBOUND MODES021001 nanoscience & nanotechnologyCondensed Matter PhysicsSurface plasmon polaritoneye diseasesElectronic Optical and Magnetic MaterialsWavelength[SPI.OPTI]Engineering Sciences [physics]/Optics / Photonic[ SPI.NANO ] Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronicssense organs[ SPI.OPTI ] Engineering Sciences [physics]/Optics / PhotonicRadiation mode0210 nano-technologyTelecommunicationsbusinessExcitation
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Vacuum Rabi Splitting and Strong-Coupling Dynamics for Surface-Plasmon Polaritons and Rhodamine 6G Molecules

2009

We report on strong coupling between surface plasmon polaritons (SPP) and Rhodamine 6G (R6G) molecules, with double vacuum Rabi splitting energies up to 230 and 110 meV. In addition, we demonstrate the emission of all three energy branches of the strongly coupled SPP-exciton hybrid system, revealing features of system dynamics that are not visible in conventional reflectometry. Finally, in analogy to tunable-Q microcavities, we show that the Rabi splitting can be controlled by adjusting the interaction time between waveguided SPPs and R6G deposited on top of the waveguide. The interaction time can be controlled with sub-fs precision by adjusting the length of the R6G area with standard lith…

Waveguide (electromagnetism)Rabi cyclesurface plasmonFOS: Physical sciencesPhysics::OpticsGeneral Physics and Astronomy02 engineering and technology01 natural sciencesMolecular physicsRhodamine 6Gchemistry.chemical_compoundstrong coupling0103 physical sciencesPolariton010306 general physicsReflectometryCondensed Matter::Quantum GasesPhysicsCondensed matter physicsSurface plasmonCavity quantum electrodynamicsdynamics021001 nanoscience & nanotechnologySurface plasmon polariton3. Good healthchemistrypolariton0210 nano-technologyPhysics - OpticsOptics (physics.optics)Physical Review Letters
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Applications of light-matter interaction in nanosciences

2009

In this thesis, light matter interaction in nanoscale has been studied from various aspects. The interaction between surface plasmon polaritons (SPPs) and optically active organic molecules (Rhodamine 6G, Sulforhodamine 101 and Coumarine 30) and semiconducting nanocrystals (quantum dots) is studied in the weak coupling regime. In particular, a photon-SPP-photon conversion with spatially separated inand outcoupling was demonstrated by using molecules. Also, a frequency downconversion for propagating SPPs was presented by utilization of vibrational relaxation of organic molecules. A strong coupling regime was reached for Rhodamine 6G (R6G) and SPP despite the broad absorption linewidth of R6G…

Weak interactions (Nuclear physics)Quantum dotssurface plasmon polaritonsStrong interactions (Nuclear physics)Physics::OpticsPolaritonsBose-Einstein condensationMoleculesnanotieteetPlasmons (Physics)pattern transfer
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Power monitoring in dielectric-loaded plasmonic waveguides with internal Wheatstone bridges

2013

We report on monitoring the mode power in dielectric-loaded surface plasmon polariton waveguides (DLSPPWs) by measuring the resistance of gold electrodes, supporting the DLSPPW mode propagation, with internal (on-chip) Wheatstone bridges. The investigated DLSPPW configuration consisted of 1-μm-thick and 10-μm-wide cycloaliphatic acrylate polymer ridges tapered laterally to a 1-μm-wide ridge placed on a 50-nm-thin and 4-um wide gold stripe, all supported by a ~1.7-µm-thick Cytop layer deposited on a Si wafer. The fabricated DLSPPW power monitors were characterized at telecom wavelengths, showing very high responsivities reaching up to ~6.4 μV/μW (for a bias voltage of 245 mV) and the operati…

Wheatstone bridgeMaterials sciencebusiness.industryPhotonic integrated circuitBiasing02 engineering and technologyDielectric021001 nanoscience & nanotechnology01 natural sciencesSurface plasmon polaritonAtomic and Molecular Physics and Opticslaw.invention010309 opticsWavelengthOpticslaw0103 physical sciencesElectrodeWafer0210 nano-technologybusinessOptics Express
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Chemical Interface Damping Depends on Electrons Reaching the Surface.

2017

Metallic nanoparticles show extraordinary strong light absorption near their plasmon resonance, orders of magnitude larger compared to nonmetallic nanoparticles. This "antenna" effect has recently been exploited to transfer electrons into empty states of an attached material, for example to create electric currents in photovoltaic devices or to induce chemical reactions. It is generally assumed that plasmons decay into hot electrons, which then transfer to the attached material. Ultrafast electron-electron scattering reduces the lifetime of hot electrons drastically in metals and therefore strongly limits the efficiency of plasmon induced hot electron transfer. However, recent work has revi…

Work (thermodynamics)ChemistryOrders of magnitude (temperature)ScatteringSurface plasmonGeneral EngineeringPhysics::OpticsGeneral Physics and Astronomy02 engineering and technologyElectron010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesGeneral Materials ScienceSurface plasmon resonanceElectric currentAtomic physics0210 nano-technologyPlasmonACS nano
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