Search results for "surface"
showing 10 items of 9345 documents
Unprecedented use of silver(I) N-heterocyclic carbene complexes for the catalytic preparation of 1,2-bis(boronate) esters.
2005
Catalytic diboration of internal and terminal alkenes with Ag(I) N-heterocyclic carbene complexes leads to 1,2-bis(boronate) esters as single intermediates, that can be oxidised towards the corresponding diols. Sanau Torrecilla, Mercedes, Mercedes.Sanau@uv.es
The use of soil water retention curve models in analyzing slope stability in differently structured soils
2017
Abstract This study analyzes whether and at what rate the parameterization of the Soil Water Retention Curve (SWRC) affects the analysis of shallow slope stability for differently structured unsaturated soils. Advanced empirical or physically-based equations of SWRCs have been proposed in literature to describe soil systems characterized by the so-called bimodal porous domain. In unsaturated soils, SWRC affects the stability assessment in two ways. It influences the resistance properties in terms of shear strengths, which depend on the soil water suction; and it affects the hydrological process modeling (e.g. infiltration) directly influencing soil moisture patterns and indirectly influenci…
Continuous Discharge Monitoring Using Non-contact Methods for Velocity Measurements: Uncertainty Analysis
2014
At gauged site, water stage and discharge hydrographs can be related also during unsteady flow conditions, using the one-dimensional diffusive hydraulic model, DORA, and exploiting sporadic surface velocity measurements carried out with a radar sensor, during the rising limb of the flood. Indeed, starting from the measured surface velocity, the application of a simplified entropic velocity distribution model allows obtaining the benchmark discharge for the Manning’s roughness calibration. The aim of this work is twofold. First, to address the uncertainty of the approach. Second, to detect the minimum water level along the rising limb in which the occasional surface velocity measurement shou…
Nitric oxide increases the decay of matrix metalloproteinase 9 mRNA by inhibiting the expression of mRNA-stabilizing factor HuR.
2003
Dysregulation of extracellular matrix turnover is an important feature of many inflammatory processes. Rat renal mesangial cells express high levels of matrix metalloproteinase 9 (MMP-9) in response to inflammatory cytokines such as interleukin-1 beta. We demonstrate that NO does strongly destabilize MMP-9 mRNA, since different luciferase reporter gene constructs containing the MMP-9 3' untranslated region (UTR) displayed significant reduced luciferase activity in response to the presence of NO. Moreover, by use of an in vitro degradation assay we found that the cytoplasmic fractions of NO-treated cells contained a higher capacity to degrade MMP-9 transcripts than those obtained from contro…
Involvement of KSRP in the post-transcriptional regulation of human iNOS expression–complex interplay of KSRP with TTP and HuR
2005
We purified the KH-type splicing regulatory protein (KSRP) as a protein interacting with the 3'-untranslated region (3'-UTR) of the human inducible nitric oxide (iNOS) mRNA. Immunodepletion of KSRP enhanced iNOS 3'-UTR RNA stability in in vitro-degradation assays. In DLD-1 cells overexpressing KSRP cytokine-induced iNOS expression was markedly reduced. In accordance, downregulation of KSRP expression increases iNOS expression by stabilizing iNOS mRNA. Co-immunoprecipitations showed interaction of KSRP with the exosome and tristetraprolin (TTP). To analyze the role of KSRP binding to the 3'-UTR we studied iNOS expression in DLD-1 cells overexpressing a non-binding mutant of KSRP. In these ce…
The 3'-UTR of the mRNA coding for the major protein kinase C substrate MARCKS contains a novel CU-rich element interacting with the mRNA stabilizing …
2003
The expression of the major protein kinase C substrate MARCKS (myristoylated alanine-rich C kinase substrate) is controlled by the stability of its mRNA. While the MARCKS mRNA is long living in quiescent fibroblasts (t1/2 = 14 h), its half-life time is drastically reduced (t1/2 = 2 h) in cells treated with phorbol esters to activate protein kinase C (PKC) or treated with growth factors. In a first step to study the underlying mechanism we identified both a cis-element on the MARCKS mRNA and the corresponding trans-acting factors. Fusing the complete 3'-UTR or specific regions of the 3'-UTR of the MARCKS gene to a luciferase reporter gene caused a drastic decrease in luciferase expression to…
Assessment of Energy and Economic Effectiveness of Photovoltaic Systems Operating in a Dense Urban Context
2013
A methodology that permits testing the level of integration of the photovoltaic technology in urban areas is presented. The percentage of coverage of the electricity demand of grid-connected photovoltaic systems installed on the roofs of buildings were investigated in a district of the city of Palermo (Sicily). After classifying roofs according to their shape, orientation and pitch by means of satellite images provided by Google Earth, the ratio of the productivity of the PV systems and the consumption of electricity of the households was analysed. The results of the energy assessment have been screened considering the economic feasibility of grid-connected photovoltaic systems: the energy …
La distribución espacial de hogares perceptores de prestaciones económicas individualizadas: una comparación de casos
2021
El análisis de las desigualdades socioespaciales ha constituido una línea de investigación destacada en el ámbito de las ciencias sociales. No obstante, la cuestión de la desigual proyección territorial de las políticas sociales en el interior de las ciudades ha recibido una menor atención académica. En este artículo se analizan, desde una perspectiva comparada, los patrones de distribución espacial de los hogares perceptores de Prestaciones Económicas Individualizadas (PEI) en dos municipios de la Comunidad Valenciana (España): Bétera y Torrent. Para ello, se implementan distintas técnicas de análisis de puntos espaciales y de Análisis Exploratorio de Datos Espaciales (AEDE). Los resultado…
Conflictos y desarrollos del imaginario colectivo: el paisaje de la Albufera y el Saler
2017
La Dehesa del Saler forma parte de la Albufera, el espacio más problemático y al mismo tiempo, el más emblemático del patrimonio paisajístico valenciano. Su análisis no podría estar separado de una construcción histórica polifónica, tejida por un lado por los múltiples discursos que forman la historia del espacio real, humano y paisajístico y, a la vez, por aquellas voces que configuran un imaginario cultural con fuertes valores identitarios. The Dehesa of the Saler forms a part of the Albufera lagoon, the most problematic, and in the same time, the most emblematic space of the Valencian landscape heritage. Its analysis might not be separated from a historical polyphonic construction, woven…
Vivienda pública y estado de bienestar en España: balance y estado de la cuestión en la época del COVID-19
2021
La presente investigación se centra en analizar la trayectoria de la política pública de vivienda en España para el periodo 1956-2020 enfatizando en la emergencia social y habitacional a lo largo de sesenta años al objeto de introducir la coyuntura actual y los retos futuros en el escenario post pandemia. Para ello, se ha realizado una búsqueda exhaustiva en bases de datos jurídicas a partir de la especificación de una serie de descriptores analíticos, así como la búsqueda en fuentes secundarias de tipo bibliográfico y estadístico. El artículo profundiza en la trayectoria de la política pública de vivienda a través de los distintos marcos de actuación a lo largo de sesenta años, su comparat…