Search results for "suspensio"
showing 10 items of 266 documents
Which factors affect the choice of the inhaler in chronic obstructive respiratory diseases?
2015
Inhalation is the preferred route of drug administration in chronic respiratory diseases because it optimises delivery of the active compounds to the targeted site and minimises side effects from systemic distribution. The choice of a device should be made after careful evaluation of the patient's clinical condition (degree of airway obstruction, comorbidities), as well as their ability to coordinate the inhalation manoeuvre and to generate sufficient inspiratory flow. These patient factors must be aligned with the specific advantages and limitations of each inhaler when making this important choice. Finally, adherence to treatment is not the responsibility of the patient alone, but should …
𝔸1-contractibility of affine modifications
2019
We introduce Koras–Russell fiber bundles over algebraically closed fields of characteristic zero. After a single suspension, this exhibits an infinite family of smooth affine [Formula: see text]-contractible [Formula: see text]-folds. Moreover, we give examples of stably [Formula: see text]-contractible smooth affine [Formula: see text]-folds containing a Brieskorn–Pham surface, and a family of smooth affine [Formula: see text]-folds with a higher-dimensional [Formula: see text]-contractible total space.
Transitive Anosov flows and Axiom-A diffeomorphisms
2009
AbstractLet M be a smooth compact Riemannian manifold without boundary, and ϕ:M×ℝ→M a transitive Anosov flow. We prove that if the time-one map of ϕ is C1-approximated by Axiom-A diffeomorphisms with more than one attractor, then ϕ is topologically equivalent to the suspension of an Anosov diffeomorphism.
Un exemple de flot d'Anosov transitif transverse à un tore et non conjugué à une suspension
1994
AbstractWe construct an example of transitive Anosov flow on a compact 3-manifold, which admits a transversal torus and is not the suspension of an Anosov diffeomorphism.
Mineralogical and chemical variability of fluvial sediments 2. Suspended-load silt (Ganga–Brahmaputra, Bangladesh)
2011
Sediments carried in suspension represent a fundamental part of fluvial transport. Nonetheless, largely because of technical problems, they have been hitherto widely neglected in provenance studies. In order to determine with maximum possible precision the mineralogy of suspended load collected in vertical profiles from water surface to channel bottom of Rivers Ganga and Brahmaputra, we combined Raman spectroscopy with traditional heavy-mineral and X-ray diffraction analyses, carried out separately on low-density and dense fractions of all significant size classes in each sample (multiple-window approach). Suspended load resulted to be a ternary mixture of dominant silt enriched in phyllosi…
Electrophoretic mobility of electrostatically interacting colloidal spheres
2004
We have measured the electrophoretic mobility μ = vE/E (where E is the electric field strength and vE the electrophoretic velocity) of highly charged colloidal spheres in deionized aqueous suspension at particle number densities n between 0.15 and 150 µm−3. Under these conditions the system exhibits fluid or crystalline order. We used laser Doppler velocimetry to determine the electrophoretic velocities vE as spatially averaged particle velocities from both integral and spatially resolved measurements. With this approach we were for the first time able to extend measurements far into the crystalline region of the phase diagram. We found μ to be constant at low n while at large n we observe …
High-Generation Amphiphilic Janus-Dendrimers as Stabilizing Agents for Drug Suspensions
2018
Pharmaceutical nanosuspensions are formed when drug crystals are suspended in aqueous media in the presence of stabilizers. This technology offers a convenient way to enhance the dissolution of poorly water-soluble drug compounds. The stabilizers exert their action through electrostatic or steric interactions, however, the molecular requirements of stabilizing agents have not been studied extensively. Here, four structurally related amphiphilic Janus-dendrimers were synthesized and screened to determine the roles of different macromolecular domains on the stabilization of drug crystals. Physical interaction and nanomilling experiments have substantiated that Janus-dendrimers with fourth gen…
Critical assessment of particle size analysis of porous silica microbead high-performance liquid chromatographic packings by photosedimentation
1979
Abstract Particle size analysis of commercial spherical silica packings of graduated pore size by means of photosedimentation (PS) is critically examined and compared to results obtained by microscopy. To avoid particle fractionation, the suspension prepared for PS measurements should be subjected to gentle ultrasonic treatment. For computing the particle size distribution, the effective density of solvent-filled porous particles has to be inserted into the Stokes equation. Reproducibility of d p , estimated by PS is found to be largely dependent upon the accuracy of the specific pore volume determination. Satisfactory agreement of data between PS and microscopy is obtained for all products…
Rheological and Flocculation Analysis of Microfibrillated Cellulose Suspension Using Optical Coherence Tomography
2018
A sub-micron resolution optical coherence tomography device was used together with a pipe rheometer to analyze the rheology and flocculation dynamics of a 0.5% microfibrillated cellulose (MFC) suspension. The bulk behavior of the MFC suspension showed typical shear thinning (power-law) behavior. This was reflected in a monotonously decreasing floc size when the shear stress exceeded the yield stress of the suspension. The quantitative viscous behavior of the MFC suspension changed abruptly at the wall shear stress of 10 Pa, which was reflected in a simultaneous abrupt drop of the floc size. The flocs were strongly elongated with low shear stresses. With the highest shear stresses, the flocs…