Search results for "symptoms"

showing 10 items of 713 documents

Clinical and anti-inflammatory effects of ultra-short preseasonal vaccine to Parietaria in asthma

2013

Objective: The ultra-short course preseasonal allergy vaccine, containing the adjuvant monophosphoryl lipid A (MPL), is effective in treating allergic symptoms; however, the efficacy in controlling asthmatics symptoms has not been fully demonstrated. We aimed at evaluating whether the ultra-short preseasonal course of immunotherapy contributes to asthma control. Methods: Four subcutaneous injections of the active product (Pollinex Quattro) were administered, before the pollen season, to 20 Parietaria-sensitive mild, untreated asthmatics (M/F: 12/8; age: 38 ± 14 years). After the screening visit (visit 1), asthma control was assessed by the Asthma Control Test (ACT) immediately before the fi…

AdultMalePulmonary and Respiratory MedicineBreath TestParietariamedicine.drug_classmedicine.medical_treatmentMonophosphoryl Lipid Aairway inflammationSettore MED/10 - Malattie Dell'Apparato RespiratorioNitric OxideAnti-inflammatoryAllergic symptomsmedicineHumansPharmacology (medical)LungAsthmaInflammationVaccinesbiologybusiness.industryAllergy vaccineImmunotherapyMiddle Agedmedicine.diseasebiology.organism_classificationAsthmaParietariaquality of lifeBreath TestsDesensitization ImmunologicImmunologyFemaleimmunotherapybusinessVaccineAdjuvantHumanTherapeutic Advances in Respiratory Disease
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Depression and religiosity in older age

2011

Abstract We investigated the hypothesis that religious commitment could help counter general affective distress, accompanying depressive symptoms, in older age. A total of 34 older adults, all catholic believers, completed self-reported questionnaires on the presence of depressive symptoms, religiosity, health, worry, and the style of coping with stress. The depressive and non-depressive subgroups were then created. The prevalence of depressive symptoms was 50%, with the substantial predominance of females. Regression analyses indicate that health expectations and worry significantly worsen with increasing intensity of depressive symptoms. The results further show that religious engagement …

AdultMaleReligious commitmentAgingCoping (psychology)medicine.medical_specialtymedia_common.quotation_subjectAffective distresslcsh:MedicineReligiosityAgemedicineHumanspsychosomatic healthPsychiatryDepressive symptomsAgedmedia_commonAged 80 and overResearchReligion and Medicinelcsh:RGeneral MedicineMiddle AgedPrognosisreligiosityDistressMedicine public healthdepressionFemaleWorryPsychologyEuropean Journal of Medical Research
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The Decreasing Prevalence of the Arcuate Foramen

2018

[Background]: The arcuate foramen (AF), or ponticulus posticus, is an anatomic variant of the first cervical vertebra that consists of a complete or partial osseous bridge over the groove for the vertebral artery and extends from the posterior aspect of the superior articular facet to the superior lateral border of the posterior arch. The AF has been associated with clinical symptoms, such as headache, migraine, neck pain, shoulder pain, arm pain, and vertebral artery dissection. We aimed to test whether the prevalence of the AF has decreased in the modern human population over the past centuries as a result of reduction in inbreeding and endogamy.

AdultMaleRural Populationmusculoskeletal diseases0301 basic medicinemedicine.medical_specialtyUrban PopulationVertebral artery dissectionVertebral arteryPopulationConsanguinityYoung Adult03 medical and health sciences0302 clinical medicinemedicine.arteryHumansMedicineProspective StudiesVertebral arteryeducationSigns and symptomsAgedAged 80 and overArcuate forameneducation.field_of_studyNeck painbusiness.industryAnatomic VariationMiddle Agedmusculoskeletal systemmedicine.diseaseConfidence intervalSpineSurgeryBridge (graph theory)ArchaeologyMigraineRisk factorsCervical atlasFemaleSurgery030101 anatomy & morphologyNeurology (clinical)medicine.symptomAnatomybusiness030217 neurology & neurosurgery
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Autonomic markers associated with generalized social phobia symptoms: heart rate variability and salivary alpha-amylase.

2016

The study of autonomic nervous system changes associated with generalized social phobia (GSP) disorder has increased in recent years, showing contradictory results. The present study aimed to evaluate how young people with GSP reacted before, during, and after exposure to the Trier Stress Social Test (TSST), focusing on their autonomic changes (heart rate variability (HRV) and salivary alpha-amylase (sAA)) compared to a control group (non-GSP). Some psychological variables were also considered. Sex was specifically studied as a possible modulator of autonomic fluctuations and psychological state. Eighty young people were randomly distributed into two counterbalanced situations: stress condi…

AdultMaleSalivaAdolescentPhysiologyAutonomic Nervous System050105 experimental psychologyDevelopmental psychology03 medical and health sciencesBehavioral NeuroscienceYoung Adult0302 clinical medicinestomatognathic systemHeart RateSurveys and QuestionnairesHeart rateHeart rate variabilityHumans0501 psychology and cognitive sciencesEndocrine and Autonomic SystemsSymptoms heart05 social sciencesPhobia SocialPsychiatry and Mental healthAutonomic nervous systemAffectNeuropsychology and Physiological PsychologyMoodSalivary alpha-AmylasesFemaleStress conditionsPsychology030217 neurology & neurosurgeryBiomarkersStress PsychologicalClinical psychologyStress (Amsterdam, Netherlands)
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Italian version of the MD Anderson Symptom Inventory-Head and Neck Module: linguistic validation

2015

Background: Head and neck cancer (HNC) patients can experience symptoms due to the tumor itself or to the treatment, with an impact on health-related quality of life (HRQoL). Patient-reported outcome (PRO) measures pertaining to HRQoL are used in medical research and to support clinical decisions. PRO instrument applicability and cultural adaptation must be tested for each population. The aim of this study is to linguistically validate the Italian translation of the M.D. Anderson Symptom Inventory—Head and Neck Module (MDASI-HN). Methods: Following forward and backward translation of the items of the English MDASI-HN into Italian, it was administered along with a cognitive debriefing to HNC…

AdultMaleSettore M-PSI/01 - Psicologia Generalemedicine.medical_specialtyAdolescentPopulationLinguistic validationItalian MDASI-HNYoung AdultQuality of lifeOutcome Assessment Health CarePatient symptomMedicineHumansPatient symptomsTranslationsHead and neckeducationHead and neck cancerPatient-reported outcomeAgedLanguageAged 80 and overeducation.field_of_studybusiness.industryNursing researchHead and neck cancerReproducibility of ResultsLinguisticsHead and neck cancer; Patient symptoms; Patient-reported outcome; Italian MDASI-HN;Middle Agedmedicine.diseasehumanitiesPatient Outcome AssessmentOncologyItalyHead and Neck NeoplasmsPhysical therapyQuality of LifePatient-reported outcomeFemaleSelf ReportSymptom Assessmentbusiness
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Proposal for a new staging system for osteoradionecrosis of the mandible

2014

A new staging system for osteoradionecrosis of the mandible has been retrospectively applied to a group of 31 patients. In this system clinicoradiographic signs and symptoms are incorporated in a simplified manner. For imaging purposes the use of plain radiographs such as periapical films and panoramic radiographs is recommended, mainly because of their readily availability. The presented staging system seems well reproducible, facilitating the comparison of study groups dealing with the various issues of osteoradionecrosis of the mandible. It is yet to be evaluated whether the presently proposed staging system is useful for management purposes. Key words:Osteoradionecrosis, jaw bones, mand…

AdultMaleStudy groupsOsteoradionecrosisRadiographyDentistrySigns and symptomsOdontologíaSeverity of Illness IndexSDG 3 - Good Health and Well-beingmedicineHumansMandibular DiseasesGeneral DentistryStaging systemAgedRetrospective StudiesAged 80 and overOrthodonticsOral Medicine and Pathologybusiness.industryResearchMandibleMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludOsteoradionecrosisOtorhinolaryngologyMandibular DiseasesUNESCO::CIENCIAS MÉDICAS/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleSurgeryPlain radiographsbusiness
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The concept of a surrogate is ill adapted to intensive care: Criteria for recognizing a reference person

2016

IF 2.445; International audience; Purpose: In the intensive care unit (ICU), caregivers may find it difficult to identify a suitable person in the patient's entourage to serve as a reference when there is no official surrogate.Methods: We developed a 12-item questionnaire to identify factors potentially important for caregivers when identifying a reference person. Each criterion was evaluated as regards its importance for the role of reference. Responses were on a scale of 0 (not important) to 10 (extremely important). We recorded respondent's age, job title, and number of years' ICU experience. The questionnaire was distributed to all health care professionals in 2 French ICUs.Results: Amo…

AdultMaleUnit patientsDesignationCritical CareMedical informationDecision MakingPatient AdvocacyCritical Care and Intensive Care MedicinePatient advocacylaw.inventionYoung Adult03 medical and health sciences0302 clinical medicineNursinglawPhysiciansSurveys and QuestionnairesIntensive care[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyHealth careHumansMedicineYoung adultFamily-membersAgedResponse rate (survey)Ethicsbusiness.industryQuestionnaireSurrogate030208 emergency & critical care medicineMiddle AgedIntensive care unitProxy3. Good healthCaregivers030228 respiratory systemScale (social sciences)Intensive careRespondentSymptomsFemalebusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Correlations between hormones, physical, and affective parameters in aging urologic outpatients.

2004

Abstract Objective: To determine the relationship between sex hormones, physical complaints, depression, sexuality, and life satisfaction in aging men. Methods: 263 outpatients aged 40 years and above ( M =56.2; 40–84 years) were recruited from 6 andrological outpatient departments in Germany to evaluate "aging male" symptoms. Subjects were assessed by standardised self-report questionnaires, physical, and endocrinological examination. Results: Total and free testosterone as well as DHEA-S (dehydroepiandrosterone-sulfate) levels decreased significantly with age. SHBG (sex hormone binding globulin) and LH (luteinizing hormone) increased; estradiol remained unchanged. Inactivity, lower urinar…

AdultMaleUrologic Diseasesmedicine.medical_specialtyAgingmedicine.drug_classUrologyPhysiologySex hormone-binding globulinLower urinary tract symptomsInternal medicineSurveys and QuestionnairesOutpatientsmedicineHumansGonadal Steroid HormonesDepression (differential diagnoses)AgedAged 80 and overbiologybusiness.industryDepressionTestosterone (patch)Middle AgedAndrogenmedicine.diseaseSexual desireErectile dysfunctionEndocrinologybiology.proteinQuality of LifebusinessLuteinizing hormoneSexualityEuropean urology
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Urological dysfunctions in patients with Parkinson’s disease: clues from clinical and non-invasive urological assessment

2018

Abstract Background Autonomic nervous system dysfunction, common in patients with Parkinson’s disease (PD), causes significant morbidity and it is correlated with poor quality of life. To assess frequency of urinary symptoms in patients with PD, without conditions known to interfere with urinary function. Methods Non-demented PD patients were consecutively enrolled from the outpatients clinic of our department. Scales investigating motor and non-motor symptoms were carried out. Evaluation of urinary dysfunctions was carried out using the AUTonomic Scale for Outcomes in Parkinson’s disease (SCOPA-AUT) questionnaire. Patients underwent noninvasive urological studies (nUS), including uroflowme…

AdultMaleUrologic Diseasesmedicine.medical_specialtyNeurologyParkinson's diseaseUrinary systemAutonomic dysfunction030232 urology & nephrologyNon-motor symptomsUrinary symptomsDiseaseNon-motor symptomlcsh:RC346-429SCOPA-AUT03 medical and health sciences0302 clinical medicineSurveys and QuestionnairesInternal medicinemedicineHumansNeurochemistryStage (cooking)lcsh:Neurology. Diseases of the nervous systemAgedbusiness.industryAUTonomic SCale for outcomes in Parkinson’s diseaseParkinson DiseaseGeneral MedicineMiddle AgedUrinary functionmedicine.diseaseAutonomic Nervous System DiseasesQuality of LifeParkinson’s diseaseFemaleSettore MED/26 - NeurologiaNeurology (clinical)Neurosurgerybusiness030217 neurology & neurosurgeryBMC Neurology
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Cross validation of the factor structure of the 20-item Toronto Alexithymia Scale: An Italian multicenter study

1996

The 20-item Toronto Alexithymia Scale (TAS-20) has been shown in previous research to measure a general dimension of alexithymia with three intercorrelated factors. This study evaluated the reliability and factorial validity of an Italian translation of the TAS-20 in a group of normal adults (N = 206) and in a mixed group of medical and psychiatric outpatients (N = 642). Using confirmatory factor analyses, the previously established three-factor model of the TAS-20 was found to be replicable in both groups. In addition, the Italian TAS-20 demonstrated adequate estimates of internal reliability and test-retest reliability. Although evaluation of the convergent, discriminant, and concurrent v…

AdultMaleanimal structuresPsychometricsPsychometricsConcurrent validityValidityTest validityModels PsychologicalSampling StudiesDevelopmental psychologyToronto Alexithymia ScaleAlexithymiaRating scalemedicineHumansAffective SymptomsAgedPsychiatric Status Rating ScalesChi-Square Distributionmedicine.diagnostic_testReproducibility of ResultsMiddle AgedTranslatingmedicine.diseasePsychiatry and Mental healthClinical PsychologyItalyScale (social sciences)FemaleFactor Analysis StatisticalPsychologyClinical psychologyJournal of Psychosomatic Research
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