Search results for "talin"
showing 10 items of 126 documents
How do illiterate adults react to metalinguistic training?
2013
The present study focuses on the capacity of illiterate adults to master three different metalinguistic tasks: judgment of phonological length of words, initial consonant deletion, and lexical segmentation of sentences. Illiterates’ performance, during a pre-test and after training, was compared with that of literates and partial illiterates (adults at the beginning of the process of acquiring literacy) who received the same training. In the pre-test, illiterates were lower than literates in the three tasks; and partial-illiterates were at an intermediate level in two of the tasks. The three groups profited from the training, especially illiterates and partial-illiterates for whom improveme…
A influência do método de armazenamento na transparência do cristalino de porco
2019
Este artículo se ha publicado de forma definitiva en: http://www.scielo.br/pdf/abo/v82n1/0004-2749-abo-82-01-0056.pdf Purpose: The porcine eye is frequently used as a research model. This paper analyzes the effect of different storage methods on the transparency of pig crystalline lens. Methods: A spectral transmission curve (from 220 to 780 nm) for the crystalline lens was determined experimentally after storage in different conditions: saline solution, formalin, castor oil, and freezing at -80°C. The total transmission in the visible spectrum, which was used as an index of transparency, was calculated from these curves. For comparative purposes, fresh lenses were evaluated and used as con…
A classroom intervention on Spanish grammar and writing: the use of the past tense with secondary school students / La intervención didáctica en el a…
2015
AbstractThis article presents an innovative experience which links grammar teaching with writing, following the premises of the Grammar Didactic Sequences (GDS) with one basic objective: to create a situation in which students learn to reflect on the language they use and are able to use these reflections to improve their writing. The GDS, focused on the use of past tense verb forms, was carried out with fourth-year secondary school students in Spain. This article highlights the difficulties experienced by students when using grammatical concepts as elements to control usage and the importance of revising texts in order to create metalinguistic awareness in a recursive didactic process: fro…
Quantitation of talinolol in rat plasma by LC-MS-MS.
2010
The aim of this study was to develop and validate an assay based on liquid chromatography-tandem mass spectrometry to quantitate talinolol in rat plasma. After a simple protein precipitation step, separation was performed by reversed-phase liquid chromatography using gradient elution with acetonitrile-water-formic acid. Electrospray ionization in the positive ion mode with multiple reaction monitoring was used to analyze talinolol employing propranolol as internal standard. The calibration curve for talinolol was linear over the concentration range 1-250 ng/mL with a correlation coefficient0.995. The method was sensitive (limit of quantitation, 1 ng/mL) and had acceptable accuracy (85-115% …
Stalinismi musiikissa : narodnost-käsite Neuvostoliiton musiikkipolitiikan diskursseissa 1930-luvulla
2016
Tässä maisterintutkielmassa tarkasteltiin yhden sosialistisen realismin alakäsitteen, narodnostin, merkitystä ja asemaa Neuvostoliiton musiikkipolitiikassa 1930-luvulla. Narodnost-käsitteen merkitystä selvitettiin suhteessa 1930-luvun Neuvostoliiton laajempiin poliittisiin diskursseihin, mikä toi esille Neuvostoliiton virallisen taidesuuntauksen muotoutumisen yhteyden tuon ajan historialliseen ja poliittiseen kontekstiin. Käsitteen määrittelyssä hyödynnettiin kahta historian ja kielen suhdetta tarkastelevaa teoreettista viitekehystä, diskurssintutkimusta ja käsitehistoriaa. Näiden teorioiden pohjalta luotiin lähestymistapa, jossa käsitteiden nähdään muodostuvan diskursseista. Näin ollen käs…
METALANG. Protocolo franco-español de exploración de habilidades metalingüísticas en niños de 6 a 9 años: un estudio preliminar
2012
International audience; In this work are described the principles of functional-pragmatic and the reasons for developing an exploration protocol for natural metalinguistic abilities. This study explains the base hypothesis and structure of METALANG protocol. This protocol consists in a Test and a Questionnaire for parents with two different scales: A = Ability, B = Frequency. Each element of the protocol has 6 sections and 40 items. It is performed a preliminary contrast with 12 subjects aged 6 to 9 years. Among the 12 subjects, 4 were diagnosed with dysphasia. METALANG shows high scores in reliability and internal consistency. This result confirms the hypothesis that it is possible a joint…
Identification of P-glycoprotein substrates and inhibitors among psychoactive compounds--implications for pharmacokinetics of selected substrates.
2004
Abstract The pharmacokinetics of antipsychotic drugs has become an integral part in understanding their pharmacodynamic activity and clinical effects. In addition to metabolism aspects, carrier-mediated transport, particularly secretion by ABC transporters, has been discussed as potentially relevant for this group of therapeutics. In this study, the psychoactive compounds perphenazine, flupentixol, domperidone, desmethyl clozapine, haloperidol, fluphenazine, fluvoxamine, olanzapine, levome-promazine, perazine, desmethyl perazine, clozapine, quetiapine and amisulpride were characterized in terms of P-glycoprotein (P-gp) affinity and transport. Experimental methods involved a radioligand disp…
β1-Integrin Cytoplasmic Subdomains Involved in Dominant Negative Function
1998
The beta1-integrin cytoplasmic domain consists of a membrane proximal subdomain common to the four known isoforms ("common" region) and a distal subdomain specific for each isoform ("variable" region). To investigate in detail the role of these subdomains in integrin-dependent cellular functions, we used beta1A and beta1B isoforms as well as four mutants lacking the entire cytoplasmic domain (beta1TR), the variable region (beta1COM), or the common region (beta1 deltaCOM-B and beta1 deltaCOM-A). By expressing these constructs in Chinese hamster ovary and beta1 integrin-deficient GD25 cells (Wennerberg et al., J Cell Biol 132, 227-238, 1996), we show that beta1B, beta1COM, beta1 deltaCOM-B, a…
The role of language on the reversal error. A study with bilingual Basque-Spanish students
2019
The reversal error is a prevalent phenomenon that consists of reversing the relationship between two variables when writing equations from comparison in verbal language. A study with 169 Basque/Spa...
Revista iberoamericana de educación
2012
Título, resumen y palabras clave en español, portugués e inglés Monográfico con el título: "Didáctica de la Lengua y la Literatura" Resumen tomado de la publicación Se centra en la relación didáctica entre la gramática, entendida como reflexión sobre la lengua, y la mejora del uso lingüístico. Para ello, se aborda, en primer lugar, la finalidad de la enseñanza de las lenguas en los currículos escolares y el papel que se atribuye a la reflexión gramatical en ellos. A continuación, se muestra la importancia de las investigaciones sobre la actividad metalingüística de los hablantes para un planteamiento de la gramática en función del uso. Por último, se revisan algunas vías exploradas por la i…