Search results for "tear"

showing 10 items of 222 documents

Identification of drying oils used in pictorial works of art by liquid chromatography of the 2-nitrophenylhydrazides derivatives of fatty acids.

2004

A new HPLC-UV-Vis method for identification of drying oils from binding media or protective film used in pictorial works of art prior to conservation or restoration is proposed. Chromophore derivatization of fatty acids released by hydrolysis of structural drying oils is studied. The derivatization reagent selected was 2-nitrophenylhydrazine with 1-ethyl-3-(3-dimethyl animopropyl)carbodiimide hydrochloride/pyridine as catalyst. This reaction was carried out using microwave heating. Mobile phase was methanol/water/n-propanol/acetic acid (80:14:5:1) running in isocratic mode. Absorbance was measured at 400nm. In these conditions, hydrazides of myristic, palmitic, oleic, and stearic acids were…

chemistry.chemical_compoundHydrolysisOleic acidChromatographychemistryReagentDrying oilAcid hydrolysisStearic acidDerivatizationHigh-performance liquid chromatographyAnalytical ChemistryTalanta
researchProduct

Non-invassive assessment of the tear film and the ocular surface: Effect of contact lenses

2022

El diagnóstico y tratamiento del síndrome del ojo seco es un reto debido al carácter multifactorial de la enfermedad y la falta de un test clínico “gold standard”. Además, la falta de correlación entre los signos y síntomas de la enfermedad del ojo seco, la falta de correlación entre métricas, su baja repetibilidad, su carácter invasivo y su relativa objetividad dificulta el estudio de la película lagrimal y el diagnóstico de la enfermedad del ojo seco. En el Capítulo 1 del presente trabajo se describen las características principales de la película lagrimal y la enfermedad del ojo seco, y se realiza una revisión bibliográfica sobre técnicas no invasivas de análisis de la película lagrimal …

dry eyeocular surface:CIENCIAS MÉDICAS ::Ciencias clínicas::Oftalmología [UNESCO]meibomian glands dysfunctionUNESCO::CIENCIAS MÉDICAS ::Ciencias clínicas::Oftalmologíatear filmdry eye disease
researchProduct

Valoración de los parámetros geométricos del menisco lagrimal mediante tomografía de coherencia óptica, y su aplicación en el diagnóstico diferencial…

2022

La unidad funcional lagrimal es un sistema integral formado por las glándulas lagrimales y de Meibomio, la superficie ocular (córnea y conjuntiva) y los párpados, así como los nervios sensoriales y motores que los conectan. El mecanismo homeostático de la unidad funcional lagrimal regula la secreción y distribución de la lágrima en respuesta a las señales de la superficie ocular, siendo uno de sus principales objetivos el mantenimiento de una adecuada película lagrimal precorneal. La película lagrimal está formada por dos capas, una capa lipídica externa y un gel muco-acuoso interno en contacto con el glicocálix del epitelio corneal. De vital importancia para su formación es el menisco lagr…

dry eyeoptical coherence tomographytear meniscusUNESCO::CIENCIAS MÉDICASojo secotomografía de coherencia ópticamenisco lagrimal
researchProduct

Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells

2011

International audience; 1-Nitropyrene (1-NP) is a nitro-polycyclic aromatic hydrocarbon (nitro-PAH) present in diesel exhaust and bound to particular matter in urban air. We show that 1-NP and the referent PAH benzo(a)pyrene (BP) induce apoptosis and a lipid accumulation dependent on cytochrome P450 1A1-metabolites in mouse hepatoma cells, whereas 1-amino-pyrene had no effect. The caspase inhibitor, N-benzyloxycarbonyl-Val-Ala-Asp(O-Me) fluoromethyl ketone (Z-VAD-fmk), inhibits 1-NP-induced apoptosis, but failed to alter 1-NP-triggered lipid accumulation determined by Nile red staining. We further show that cholesterol and fatty acid contents are modified after nitro-PAH exposure and that 1…

endoplasmic-reticulum stressMESH: PyrenesHepatoma cellsliver-cellsactivated protein-kinaseApoptosisAMP-Activated Protein KinasesToxicologyMESH: Liver Neoplasms ExperimentalMicechemistry.chemical_compoundMESH: CholesterolLiver Neoplasms ExperimentalMESH: AnimalsMESH: AMP-Activated Protein KinasesStearoyl-CoA desaturase 1CaspaseMESH: Lipid Metabolismchemistry.chemical_classificationhuman macrophages0303 health sciencesPyrenesbiology8-tetrachlorodibenzo-p-dioxin tcdd030302 biochemistry & molecular biologyGeneral Medicineinhibition[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biomolecules [q-bio.BM]CholesterolBiochemistry[SDV.TOX]Life Sciences [q-bio]/ToxicologyCaspaseslipids (amino acids peptides and proteins)stearoyl-coaStearoyl-CoA DesaturaseMESH: Cell Line Tumor[SDV.BC]Life Sciences [q-bio]/Cellular Biology03 medical and health sciencesMESH: Benzo(a)pyreneCell Line Tumor1-NitropyreneBenzo(a)pyreneAnimalsFatty acidsProtein kinase AMESH: Mice030304 developmental biologyaromatic-hydrocarbonsMESH: CaspasesCholesterolMESH: Apoptosisc-srcFatty acidAMPKCytochrome P450Lipid MetabolismMolecular biologychemistryApoptosisMESH: Stearoyl-CoA Desaturasebiology.proteinStearoyl-CoA desaturase-1desaturaseToxicology Letters
researchProduct

Lasten ja nuorten kunto : tutkittavaa riittää

2023

fyysinen kuntonuoretviitearvotlapset (ikäryhmät)seurantapitkittäistutkimusterveysinterventio
researchProduct

Video display terminal use and dry eye: preventive measures and future perspectives

2022

Background: Dry eye disease (DED) is a common cause of ocular pain and discomfort. Dry eye disease (DED) stems from a loss-of-tear film homeostasis and is frequently seen in video display terminal (VDT) users. Video display terminal (VDT) use reduces blink rates and increases incomplete blinks, leading to tear film instability and ocular inflammation, promoting DED. Purpose: To assess and evaluate the methods for preventing VDT-associated DED and ocular discomfort. Methods: Studies were found using PubMed and Embase with the search terms: (digital visual terminal* OR computer use OR screen use OR smartphone OR display OR visual display terminal* OR computer vision syndrome OR tablet OR phon…

genetic structuresCOMPUTER VISION SYNDROMEVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Oftalmologi: 754QUALITY-OF-LIFE:Medisinske Fag: 700 [VDP]ergonomic practicesFatty Acids Omega-3tear film stabilityHumansOMEGA-3-FATTY-ACIDS TREATMENTOFFICE WORKERSInflammationMucinsOCULAR SURFACEGeneral Medicinedry eye diseaseeye diseasesvideo display terminalBLINK RATEOphthalmologySPONTANEOUS EYEBLINK ACTIVITYHIGHLY ADJUSTABLE CHAIRComputer TerminalsTearsRISK-FACTORSpreventive measuresDry Eye SyndromesFIELD INTERVENTIONVDP::Matematikk og Naturvitenskap: 400::Informasjons- og kommunikasjonsvitenskap: 420::Simulering visualisering signalbehandling bildeanalyse: 429
researchProduct

Tear production and intraocular pressure values in clinically normal eyes of whooper swans (Cygnus cygnus)

2018

The objective of this study was to determine the normal range of tear production and values of intraocular pressure (IOP) in clinically normal eyes of whooper swans (Cygnus cygnus). A total of 86 birds: 81 cygnets (6-10 weeks old) and 5 moulting – adult swans (3-6 years old) were examined in this study. Both eyes of all birds underwent a complete ophthalmic examination, including evaluation of tear production with the phenol red thread test (PRTT) and the assessment of the IOP by rebound tonometry, employing the TonoVet® device. The mean ± standard deviation of PRTT values were as follows: all cygnets (81) 22.59±3.48 mm/15s, male cygnets (45) 22.64±3.54 mm/15s, female cygnets (36) 22.53±3.4…

genetic structuresQL1-991Intraocular pressurePhenol red thread testEye Intraocular pressure Phenol red thread test Tear production Whooper swanWhooper swanOriginal Articlesense organsTear productionEyeZoologyeye diseasesOpen Veterinary Journal
researchProduct

Dangerous relationships : biases in freshwater bioassessment based on observed to expected ratios

2018

Copyright by the Ecological Society of America The ecological assessment of freshwaters is currently primarily based on biological communities and the reference condition approach (RCA). In the RCA, the communities in streams and lakes disturbed by humans are compared with communities in reference conditions with no or minimal anthropogenic influence. The currently favored rationale is using selected community metrics for which the expected values (E) for each site are typically estimated from environmental variables using a predictive model based on the reference data. The proportional differences between the observed values (O) and E are then derived, and the decision rules for status ass…

inland waters0106 biological sciencesPercentilepäätöksentekomodelling (creation related to information)010501 environmental sciencesExpected value01 natural sciencescase studylakesStatisticsviitearvotfreshwatersMathematicsevaluationEcologyEcologyBiodiversityVariance (accounting)reference valuessimulationpredictive modelsekologia6. Clean waterreference condition approachmathematical modelsEnvironmental Monitoringmallintaminenecological statusCorrection methodta1172järvetdecision makingtapaustutkimusRiversAnimalssimulointiekologinen tila0105 earth and related environmental sciencesta112bioassessmentluokitus (toiminta)010604 marine biology & hydrobiologyEcological assessmentDecision rulesisävedetInvertebratesReference data13. Climate actionta1181classification errormatemaattiset mallitarviointiQuantileEcological Applications
researchProduct

Determination of the Absolute Density of Fe3+ and Ni2+ Ions in Langmuir-Blodgett Films

1996

By means of the Langmuir–Blodgett (LB) technique, mono- and multilayers of Ni2+ and Fe3+ containing fatty acid salts are transferred onto silicon wafers. After thermal treatment, oxidic layers can be produced. The absolute amounts of Fe3+ and Ni2+ ions per monolayer of LB film were measured and calculated by three different methods. In the case of nickel, the amount expected from theory and preparation conditions was obtained experimentally. In contrast, about twice the number of Fe3+ ions as expected is transferred. An explanation can be given by the presence of hydroxide groups bound to iron. The mean film thickness of the oxidic layers after thermal treatment was estimated where the thic…

inorganic chemicalsX-rayAnalytical chemistrychemistry.chemical_elementSurfaces and InterfacesGeneral ChemistryThermal treatmentCondensed Matter PhysicsLangmuir–Blodgett filmSurfaces Coatings and FilmsIonchemistry.chemical_compoundNickelchemistryMonolayerMaterials ChemistryHydroxideStearic acidSurface and Interface Analysis
researchProduct

Workshop on ICES reference points (WKREF2)

2022

The ICES Workshop on ICES reference points (WKREF2) was tasked review the WKREF1 report and based on the outcome develop updated guidelines for the ICES reference points system and recommendations for ACOM consideration. The WKREF1 report has suggested 5 key recommendations to simplify and harmonise the ICES reference points framework representing a major change to the current guidelines. At WKREF2, we detailed discussions and four key concerns were raised about the proposed approach. The first related to the simplification of rules to define Blim. Around two thirds of category 1 stocks would end up as WKREF1 “Blim Type 2” where Blim would be set as a fraction of B0. The Allee effect or “de…

kalakannatvesiekosysteemitviitearvotsääntelytehokalastussaaliitmeretpopulaatiodynamiikka
researchProduct