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showing 10 items of 19001 documents

Diagnosis and Treatment of Lower Extremity Venous Thromboembolism

2020

Importance: Incidence rates for lower extremity deep vein thrombosis (DVT) range from 88 to 112 per 100 000 person-years and increase with age. Rates of recurrent VTE range from 20% to 36% during the 10 years after an initial event.Observations: PubMed and Cochrane databases were searched for English-language studies published from January 2015 through June 2020 for randomized clinical trials, meta-analyses, systematic reviews, and observational studies. Risk factors for venous thromboembolism (VTE), such as older age, malignancy (cumulative incidence of 7.4% after a median of 19 months), inflammatory disorders (VTE risk is 4.7% in patients with rheumatoid arthritis and 2.5% in those withou…

medicine.medical_specialtyVena Cava FiltersDeep vein01 natural sciencesPostthrombotic Syndromelaw.inventionFibrin Fibrinogen Degradation Products03 medical and health sciencesSex Factors0302 clinical medicineRandomized controlled trialPredictive Value of TestsRisk FactorslawInternal medicineMedical IllustrationFactor V LeidenHumansThrombophiliaMedicineCumulative incidencecardiovascular diseases030212 general & internal medicine0101 mathematicsLife StyleThrombectomyUltrasonographybusiness.industry010102 general mathematicsAge FactorsWarfarinVenous ThromboembolismGeneral Medicinemedicine.diseaseThrombosisPre- and post-test probabilitymedicine.anatomical_structureLower ExtremityPredictive value of testsWarfarinSymptom AssessmentbusinessBiomarkersFactor Xa Inhibitorsmedicine.drugJAMA
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Transverse Sinus Stenosis in Refractory Chronic Headache Patients: An Observational Study

2019

Background: Transverse sinus stenosis is a common brain MRI finding in chronic migraine (CM) and chronic tension-type headache (CTTH) patients in clinical practice; however, its clinical and diagnostic role is unclear. The aim of the study is to determine the frequency of transverse sinus stenosis in these headache patients resistant to preventive treatments and to verify whether this is a useful finding for identifying patients with intracranial hypertension. Methods: This is an observational study. Patients with refractory CM and CTTH underwent a 3T-magnetic resonance venography (MRV) before cerebrospinal fluid (CSF) opening pressure measurement. Transverse sinus stenosis was determined u…

medicine.medical_specialtyVenographylcsh:RC346-429030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineCerebrospinal fluidChronic Migrainechronic headacheInternal medicinemedicineRisk factorlcsh:Neurology. Diseases of the nervous systemSinus (anatomy)Original Researchmedicine.diagnostic_testbusiness.industrysinus stenosisrefractory headachemedicine.diseaseComorbidityStenosismedicine.anatomical_structureNeurologyConcomitantCardiologyNeurology (clinical)businessidiopathic intracranial hypertension030217 neurology & neurosurgeryMRIFrontiers in Neurology
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Estimation of serum lipids in patients with Oral Submucous Fibrosis in India

2014

Objectives: Oral submucous fibrosis (OSMF) is the most prevalent precancerous condition in India. Low levels of lipids serves as a marker and prognostic indicator in the early detection of oral precancerous and cancerous states. In spite of the high prevalence and its potential to undergo malignant transformation, this condition has not widely been investigated with respect to the serum lipid levels. In the present study, an attempt was made to analyze the complete serum lipid profile, total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL) choleste - rol, low density lipoprotein (LDL) cholesterol and very low density lipoprotein (VLDL) cholesterol in OSMF and controls. M…

medicine.medical_specialtyVery low-density lipoproteinBlood lipidsOdontologíaGastroenterologychemistry.chemical_compoundHigh-density lipoproteinInternal medicinemedicineGeneral DentistryOral Medicine and Pathologymedicine.diagnostic_testCholesterolbusiness.industryResearchmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludPrecancerous conditionEndocrinologychemistryOral submucous fibrosisLow-density lipoproteinUNESCO::CIENCIAS MÉDICASlipids (amino acids peptides and proteins)businessLipid profile
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Alveolar echinococcosis: characteristics of a possible emergence and new perspectives in epidemiosurveillance

2001

International audience; The aim of this review is to discuss the situation of alveolar echinococcosis in France, in the light of the current knowledge on its transmission patterns in the world, especially Europe. An important risk of higher contamination of the rural environment may be suspected from newly reported cases of infected foxes or voles in several countries where the disease was not found before. Furthermore, the increase of prevalence rate in foxes in Bade-Würtemberg (Germany) and Franche-Comté (France), traditionally endemic, is also in support of this new trend. Urban foxes and the spreading of infected foxes to cities may also be the cause of the extension to urban and suburb…

medicine.medical_specialtyVeterinary medicinefoxLandscape epidemiologyepidemiosurveillance030231 tropical medicinePrevalencecoprotestEchinococcus multilocularis030308 mycology & parasitologylaw.invention[ SDV.EE ] Life Sciences [q-bio]/Ecology environment03 medical and health sciences0302 clinical medicinelandscape epidemiologylawEnvironmental healthEpidemiologymedicine[SDV.EE]Life Sciences [q-bio]/Ecology environment0303 health sciencesbiologyPublic healthZoonosismedicine.diseasebiology.organism_classification3. Good health[SDV.EE] Life Sciences [q-bio]/Ecology environmentInfectious DiseasesTransmission (mechanics)GeographyEchinococcus multilocularisRural area
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Interrater reliability of ultrasound in the diagnosis of sialolithiasis

2019

 The aim of this study was to assess the interrater reliability of ultrasound for diagnosing sialolithiasis. A total of 100 consecutive patients with signs of obstructive sialadenopathy were evaluated. The patients all underwent ultrasound examinations in a standardized manner conducted by one specialist with extensive experience in the management of salivary gland disorders and proficiency in head and neck ultrasonography. The video recordings were sent to six colleagues with comparable experience without providing any further information about the patients' medical history and physical examination. The overall agreement between the seven observers was substantial, with a κ of 0.765 for th…

medicine.medical_specialtyVideo RecordingPhysical examination030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinePatient informationMedicineHumansRadiology Nuclear Medicine and imagingMedical historyHead and neckUltrasonographyObserver VariationSalivary Gland Calculi030219 obstetrics & reproductive medicinemedicine.diagnostic_testbusiness.industryUltrasoundReproducibility of Resultsmedicine.diseaseInter-rater reliabilityStenosisRadiologyUltrasonographybusiness
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Treatment of early childhood medulloblastoma by postoperative chemotherapy alone.

2005

The prognosis for young children with medulloblastoma is poor, and survivors are at high risk for cognitive deficits. We conducted a trial of the treatment of this brain tumor by intensive postoperative chemotherapy alone.After surgery, children received three cycles of intravenous chemotherapy (cyclophosphamide, vincristine, methotrexate, carboplatin, and etoposide) and intraventricular methotrexate. Treatment was terminated if a complete remission was achieved. Leukoencephalopathy and cognitive deficits were evaluated.Forty-three children were treated according to protocol. In children who had complete resection (17 patients), residual tumor (14), and macroscopic metastases (12), the five…

medicine.medical_specialtyVincristineCyclophosphamidemedicine.medical_treatmentIntelligenceBrain tumorNeuropsychological TestsCarboplatinchemistry.chemical_compoundAntineoplastic Combined Chemotherapy ProtocolsMedicineHumansCerebellar NeoplasmsCyclophosphamideEtoposideEtoposideProportional Hazards ModelsMedulloblastomaPostoperative CareChemotherapyAnalysis of Variancebusiness.industryDesmoplastic medulloblastomaRemission InductionInfantGeneral Medicinemedicine.diseaseSurvival AnalysisCarboplatinSurgeryMethotrexatechemistryChemotherapy AdjuvantVincristineChild PreschoolNeoplasm Recurrence Localbusinessmedicine.drugFollow-Up StudiesMedulloblastomaThe New England journal of medicine
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Beals–Hecht syndrome and choroidal neovascularization

2010

PURPOSE To describe a case of choroidal neovascularization (CNV) in a female diagnosed with Beals-Hecht syndrome. METHODS A retrospective, interventional case is described in a 26-year-old female complaining of metamorphopsia and visual loss in her left eye (counting fingers). The fluorescein angiogram and the optical coherence tomography supported the diagnosis of CNV. Intravitreal ranibizumab was administered. RESULTS After the third intravitreal ranibizumab, her visual acuity improved to 0.8 and the morphology of the macular area was restored. CONCLUSIONS To our knowledge this is the first report of CNV in Beals-Hecht syndrome treated with ranibizumab. Self-monitoring by periodically per…

medicine.medical_specialtyVisual acuityAmsler gridgenetic structuresmedicine.diagnostic_testbusiness.industryeye diseasesOphthalmologyChoroidal neovascularizationOptical coherence tomographyOphthalmologyBeals-Hecht syndromeMedicineFluorescein angiogramMetamorphopsiasense organsRanibizumabmedicine.symptombusinessmedicine.drugClinical Ophthalmology
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Visual processing in patients with age-related macular degeneration performing a face detection test

2017

Purpose: People with age-related macular degeneration (AMD) have difficulties in familiar face recognition and facial expression discrimination. Our aim was to evaluate the visual processing of faces in AMD patients and whether this would be improved by anti-vascular endothelial growth factor therapy. This was a prospective interventional cohort study. Patients: Twelve patients with monocular wet AMD and 6 control subjects were recruited. Face detection processes were studied using cortical event-related potentials (ERPs). Patients received 3 bevacizumab intravitreal injections to the single affected eye. At baseline and 4–6 weeks after the last injection, clinical presentation and ERPs of …

medicine.medical_specialtyVisual acuityBevacizumabgenetic structuresfacial expressionsElectroencephalographybevacizumabfacial recognitionVisual processing03 medical and health sciences0302 clinical medicineOphthalmologymedicineilmeetEEGage-related eye diseasesFace detectionta315tunnistaminenOriginal ResearchFacial expressionMonocularmedicine.diagnostic_testbusiness.industryvisuaalisuuseye diseasesta3141Clinical OphthalmologyMacular degenerationRE1-994medicine.diseaseeye diseasesOphthalmologyvisualityN170silmätaudit030221 ophthalmology & optometrysense organsmedicine.symptomrecognitionbusiness030217 neurology & neurosurgerykasvontunnistus (tietotekniikka)medicine.drugface recognitionClinical Ophthalmology
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Visual acuity and contrast sensitivity screening with a new iPad application

2016

We present a new iPad application (app) for a fast assessment of Visual Acuity (VA) and Contrast Sensitivity (CS) whose reliability and agreement was evaluated versus a commercial screening device (Optec 6500). The measurement of VA was programmed in the app in accordance with the Amblyopia Treatment Study protocol. The CS was measured with sinusoidal gratings of four different spatial frequencies: 3, 6, 12 and 18 cpd at the same contrast values of the Functional Acuity Contrast Test (FACT) included in the Optec 6500. Forty-five healthy subjects with monocular corrected visual acuities better than 0.2 logMAR participated in the agreement study. Bland-Altman analyses were performed to assess…

medicine.medical_specialtyVisual acuityVisual acuitygenetic structuresComputer sciencemedia_common.quotation_subject01 natural sciences010104 statistics & probability03 medical and health sciences0302 clinical medicineOphthalmologymedicineContrast (vision)Computer visionContrast sensitivity0101 mathematicsElectrical and Electronic Engineeringmedia_commonbusiness.industryLimits of agreementHealthy subjectsFunctional acuity contrast testHuman-Computer InteractioniPadHardware and ArchitectureTreatment studyFISICA APLICADA030221 ophthalmology & optometryScreeningSpatial frequencyArtificial intelligencemedicine.symptombusinessSensitivity (electronics)
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ATD perimetry in glaucoma and ocular hypertensive patients. A preliminar study

2007

Purpose: The new ATD perimetry assesses contrast sentivity thresholds for the three afferent sensory pathways of the visual system. Our aim is to compare contrast sensitivity to stimuli with different spatio-temporal frequencies in glaucomatous (G) and ocular hypertensive (OHT) subjects. Methods: Twenty three G and OHT subjects were selected from the ophthalmic clinic, all subjects signed an informed consent. Inclusion criteria were diagnosis of G or OHT, normal Farnsworth-Munsell color test, ametropia less than 6 D, visual acuity over 20/30, absence of previous ocular surgery and experience in perimetry. Twenty locations and the fovea were evaluated in a 60o x 40o fovea-centered field. Eig…

medicine.medical_specialtyVisual acuitybusiness.industryOcular surgeryColor testGlaucomamedicine.diseaseOphthalmologyAfferentOphthalmologymedicineStatistical analysisAnalysis of variancemedicine.symptomHigh intraocular pressurebusinessActa Ophthalmologica Scandinavica
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