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showing 10 items of 4607 documents

Exposing Empirical Links between COVID-19 Situation Report and Available Data: The Case of Nigeria

2020

Ever since the index case of COVID-19 was announced in Nigeria, the number of confirmed cases has gradually increased to 46,140 (about 4.5% of total confirmed cases in Africa) as the time of writing this article. This seemingly low number of confirmed cases has provoked heated debates among researchers. This cross-sectional study explores the Nigerian COVID-19 report to expose some links between the number of confirmed cases, testing, and some environmental conditions. The findings reveal that there is no state in Nigeria which has up to 12 confirmed cases per 10,000 population. That means, the number of confirmed COVID-19 cases is less than 0.15% of the population of people across each sta…

2019-20 coronavirus outbreakAfrican most populous nationCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Populationlcsh:MedicineNigeria010501 environmental sciences01 natural sciencesArticle03 medical and health sciences0302 clinical medicineenvironmental factors030212 general & internal medicineeducationIndex case0105 earth and related environmental scienceseducation.field_of_studypandemiclcsh:Rcorrelational studyCOVID-19low number of testingVDP::Matematikk og Naturvitenskap: 400::Matematikk: 410GeographyCorrelational studyDemographyDiseases
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Real-life evaluation of a rapid extraction-free SARS-CoV-2 RT-PCR assay (COVID-19 PCR Fast-L) for the diagnosis of COVID-19.

2021

2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)SARS-CoV-2Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Extraction (chemistry)COVID-19BiologyVirologyPolymerase Chain ReactionSensitivity and SpecificityInfectious DiseasesReal-time polymerase chain reactionLife evaluationVirologyCOVID-19 Nucleic Acid TestingHumansRNA ViralProspective StudiesLetter to the EditorJournal of medical virology
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Repeated Testing in SARS-CoV-2 Infection

2020

2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia ViralTestingReal-Time Polymerase Chain ReactionSevere Acute Respiratory SyndromeArticleBetacoronavirusRepeated testingCOVID-19 TestingPandemicHumansMedicinePandemicsbiologyClinical Laboratory Techniquesbusiness.industrySARS-CoV-2COVID-19General Medicinebiology.organism_classificationTesting SARS-CoV-2 COVID-19VirologyCoronavirus InfectionsbusinessBetacoronavirusCoronavirus InfectionsMayo Clinic Proceedings
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The COVID-19 outbreak and rheumatologic skin diseases.

2020

2019-20 coronavirus outbreakLetterCoronavirus disease 2019 (COVID-19)business.industryClinical Laboratory TechniquesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia ViralMEDLINEOutbreakCOVID-19DermatologyGeneral MedicineVirologySkin DiseasesDisease OutbreaksArthritis RheumatoidCOVID-19 TestingRisk FactorsMedicineHumansLettersbusinessCoronavirus InfectionsPandemicsDermatologic therapy
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Comparison of Reported Deaths From COVID-19 and Increase in Total Mortality in Italy

2020

This analysis compares reported deaths from COVID-19, February 23 to April 4, 2020, and total mortality in Italy from January 12 through April 4 in the years 2015 through 2020.

2019-20 coronavirus outbreakmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Pneumonia ViralMEDLINE01 natural sciences03 medical and health sciencesBetacoronavirus0302 clinical medicineCOVID-19 TestingPandemicInternal MedicineResearch LetterMedicineHumans030212 general & internal medicine0101 mathematicsMortalityMortality trendsDisease NotificationPandemicsbusiness.industryClinical Laboratory TechniquesSARS-CoV-2010102 general mathematicsCOVID-19covidPublic Reporting of Healthcare DataTotal mortalityItalyDisease NotificationEmergency medicinebusinessCoronavirus InfectionsCoronavirus Infections
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The timing of initial imaging in testicular cancer: impact on radiological findings and clinical decision making

2021

Background In testicular cancer determination of clinical stage and recommendation of therapeutic strategy after inguinal orchiectomy are based on primary imaging by CT-scan of the chest and CT- or MRI- abdomen. It has not been investigated so far, whether the imaging should be performed before or after primary testicular surgery. Staging before surgery means exposing all patients to CT radiation irrespective of ensured histologic malignancy while postoperative staging could pose a risk in biased clinical decision making by increased presence of unspecific lymph node enlargement caused by postsurgical effects. Therefore, we aimed to investigate the association between the timing of initial …

2748 UrologyMalemedicine.medical_specialtyUrologymedicine.medical_treatmentClinical Decision-Making610 Medicine & health2700 General MedicineMalignancyTesticular NeoplasmsmedicineHumansStage (cooking)Lymph nodeTesticular cancerNeoplasm StagingRetrospective StudiesInguinal orchiectomy2727 Nephrology10042 Clinic for Diagnostic and Interventional Radiologybusiness.industrymedicine.diseasemedicine.anatomical_structureNephrologyLymphatic MetastasisRadiological weaponCohortAbdomenRadiologybusinessMinerva Urology and Nephrology
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Co-Loading of Ascorbic Acid and Tocopherol in Eudragit-Nutriosomes to Counteract Intestinal Oxidative Stress

2019

The present study aimed at developing a new vesicular formulation capable of promoting the protective effect of ascorbic acid and tocopherol against intestinal oxidative stress damage, and their efficacy in intestinal wound healing upon oral administration. A pH-dependent copolymer (Eudragit&reg

3003AntioxidantVitamina CVitamina Emedicine.medical_treatmentNeuroimmunologyPhospholipidPharmaceutical Sciencelcsh:RS1-441CicatritzacióWound healingNutriose02 engineering and technologymedicine.disease_causeEudragitArticlelcsh:Pharmacy and materia medica03 medical and health scienceschemistry.chemical_compoundOral administrationmedicinePhospholipid vesiclesVitamin ETocopherolVitamin C030304 developmental biology0303 health sciencesIntestinsChromatographyVesiclePrebiotic021001 nanoscience & nanotechnologyAscorbic acidIntestinal wound healingNeuroimmunologiaIntestineschemistryAntioxidant; Eudragit; Intestinal wound healing; Nutriose; Phospholipid vesicles; 3003Antioxidant0210 nano-technologyOxidative stress
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Splenic Littoral Cell Hemangioendothelioma in a Patient With Crohn's Disease Previously Treated With Immunomodulators and Anti-TNF Agents: A Rare Tum…

2011

Th e risk of malignancy in Crohn ’ s disease (CD) has been well described. Moreover, immunomodulators, uch as azathioprine (AZA) and 6-mercaptopurine (6-MP), and biological agents, such as infl iximab and adalimumab, may promote carcinogenesis ( 1 – 3 ). Splenic littoral cell tumors are recently described tumors of vascular origin composed of endothelial cells, with typical microscopic and immunohistochemical features of splenic sinus lining cells ( 4 ). Clinical findings are not specific, and outcome is unpredictable but usually benign, although a few cases with a malignant behavior have been reported ( 5,6 ). We report a 58-year-old Caucasian man with a long history of ileocolonic CD.

6-MercaptopurineMalePathologymedicine.medical_specialtyColonic Diseasemedicine.medical_treatmentAzathioprineSplenic NeoplasmHemangioendotheliomaHemangiomaImmunosuppressive AgentImmunocompromised HostImmunologic FactorCrohn Disease6-Mercaptopurine; Azathioprine; Colonic Diseases; Crohn Disease; Gastrointestinal Agents; Hemangioendothelioma; Hemangioma; Humans; Ileal Diseases; Immunologic Factors; Immunosuppressive Agents; Male; Middle Aged; Splenic Neoplasms; Tumor Necrosis Factor-alpha; Immunocompromised Host; GastroenterologyAzathioprineGastrointestinal AgentMedicineGastrointestinal agentCrohn's diseaseHepatologyTumor Necrosis Factor-alphabusiness.industryGastroenterologyImmunosuppressionMiddle Agedmedicine.diseaseSplenic NeoplasmHemangioendotheliomaImmunologyIleal DiseaseTumor necrosis factor alphaHemangiomabusinessHumanmedicine.drugAmerican Journal of Gastroenterology
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Evaluación de la biodisponibilidad oral de isoflavonas: papel de la microbiota intestinal

2014

El papel de las isoflavonas en la salud ha despertado un interés importante recientemente. Sin embargo, pocos son los estudios rigurosos al respecto, ya que en muchas ocasiones los efectos se infieren de prácticas tradicionales en los que concurren muchas otras variables además del factor en estudio. Mayor desconocimiento existe acerca de la coadministración de varias de estas sustancias o complementos cuando es una práctica habitual. En el presente proyecto se caracteriza la influencia de suplementos de microbiota sobre la biodisponibilidad de las isoflavonas. Ambos se utilizan con frecuencia en condiciones de premenopausia o durante el climaterio para compensar transtornos asociados al mi…

:CIENCIAS MÉDICAS ::Farmacodinámica::Absorción de medicamentos [UNESCO]Glucósidos (Daidzina Genistina)IsoflavonasUNESCO::CIENCIAS MÉDICAS ::Farmacodinámica::Absorción de medicamentosBiodisponibilidad oralMicrobiota intestinalAgliconas (Daidzeína Genisteína)
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Absorción gastrointestinal de la nevirapina en la rata y potenciales interacciones farmacocinéticas con fármacos antidepresivos

2015

En la actualidad, el síndrome de la inmunodeficiencia adquirida (SIDA) es una enfermedad incurable. Sin embargo, el uso de una adecuada terapia antirretroviral reduce la morbilidad y la mortalidad relacionadas con esta enfermedad y permite retrasar su progresión clínica. El tratamiento de elección consiste en la combinación de, al menos, tres fármacos antirretrovirales, estando presente en muchas de estas combinaciones la nevirapina (NVP), un inhibidor no nucleósido de la transcriptasa inversa del virus de la inmunodeficiencia humana tipo 1 (VIH-1). En los pacientes VIH-positivos, la depresión es una de las comorbilidades psicosociales más comunes, presentando una prevalencia del 20-45 %. E…

:CIENCIAS MÉDICAS ::Farmacodinámica::Absorción de medicamentos [UNESCO]inhibición del metabolismoUNESCO::CIENCIAS MÉDICAS ::Farmacología ::Análisis de medicamentosabsorción gastrointestinalinteracción farmacocinéticavirus diseases:CIENCIAS MÉDICAS ::Farmacología ::Análisis de medicamentos [UNESCO]:CIENCIAS MÉDICAS ::Farmacodinámica::Procesos metabólicos de los medicamentos [UNESCO]biodisponibilidadimmune system diseasesUNESCO::CIENCIAS MÉDICAS ::Farmacodinámica::Absorción de medicamentosUNESCO::CIENCIAS MÉDICAS ::Farmacodinámica::Procesos metabólicos de los medicamentosnevirapinafarmacocinéticanortriptilina
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