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6533b839fe1ef96bd12a5bc2

RESEARCH PRODUCT

Co-Loading of Ascorbic Acid and Tocopherol in Eudragit-Nutriosomes to Counteract Intestinal Oxidative Stress

Octavio Díez-salesOctavio Díez-salesJosé Esteban PerisElvira Escribano-ferrerClaudia CarboneIris UsachMaryam RezvaniMaria Letizia MancaCarla CaddeoAnna Maria FaddaMaria Manconi

subject

3003AntioxidantVitamina CVitamina Emedicine.medical_treatmentNeuroimmunologyPhospholipidPharmaceutical Sciencelcsh:RS1-441CicatritzacióWound healingNutriose02 engineering and technologymedicine.disease_causeEudragitArticlelcsh:Pharmacy and materia medica03 medical and health scienceschemistry.chemical_compoundOral administrationmedicinePhospholipid vesiclesVitamin ETocopherolVitamin C030304 developmental biology0303 health sciencesIntestinsChromatographyVesiclePrebiotic021001 nanoscience & nanotechnologyAscorbic acidIntestinal wound healingNeuroimmunologiaIntestineschemistryAntioxidant; Eudragit; Intestinal wound healing; Nutriose; Phospholipid vesicles; 3003Antioxidant0210 nano-technologyOxidative stress

description

The present study aimed at developing a new vesicular formulation capable of promoting the protective effect of ascorbic acid and tocopherol against intestinal oxidative stress damage, and their efficacy in intestinal wound healing upon oral administration. A pH-dependent copolymer (Eudragit&reg

yearjournalcountryeditionlanguage
2019-01-04
10.3390/pharmaceutics11010013http://hdl.handle.net/2445/173852
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