0000000000399799

AUTHOR

Claudia Carbone

showing 4 related works from this author

Formulative and stability studies of a Citrus extract to produce novel “healthy food"

2015

nutraceuticalsfunctional foodnutraceuticals functional food Citrus by-productSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoCitrus extractCitrus by-productMMPsantioxidant capacityMMPsantioxidant capacityCitrus extractFunctional food citrus baked goods microencapsulation
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COMBINATION OF ARGAN OIL AND PHOSPHOLIPIDS FOR THE DEVELOPMENT OF AN EFFECTIVE LIPOSOME-LIKE FORMULATION ABLE TO IMPROVE SKIN HYDRATION AND ALLANTOIN…

2016

Allantoin is traditionally employed in the treatment of skin ulcers and hypertrophic scars. In the present work, to improve its local deposition in the skin and deeper tissues, allantoin was incorporated in conventional liposomes and in new argan oil enriched liposomes. In both cases, obtained vesicles were unilamellar, as confirmed by cryo-TEM observation, but the addition of argan oil allowed a slight increase of the mean diameter (∼130nm versus ∼85nm). The formulations, especially those containing argan oil, favoured the allantoin accumulation in the skin, in particular in the dermis (∼8.7μg/cm(2)), and its permeation through the skin (∼33μg/cm(2)). The performances of vesicles as skin d…

3003Pig skinfood.ingredientSwineChemistry PharmaceuticalSkin AbsorptionPharmaceutical ScienceArgan oil02 engineering and technologyAdministration Cutaneous030207 dermatology & venereal diseases03 medical and health scienceschemistry.chemical_compoundDrug Delivery Systems0302 clinical medicineAllantoinfoodDermisElastic ModulusSkin rheologymedicineAnimalsPlant OilsAllantoinSofteningPhospholipidsSkinDrug CarriersLiposomeChromatographyintegumentary systemChemistryVesicleLiposomes; Argan oil; Phospholipids; Pig skin; Turbiscan lab; Skin rheology; Skin hydrationPermeation021001 nanoscience & nanotechnologyTurbiscan labmedicine.anatomical_structureSkin hydrationArgan oilLiposomesDermatologic Agents0210 nano-technologyDrug carrierargan oil; liposomes; phospholipids; pig skin; skin hydration; skin rheology; turbiscan lab; 3003
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Co-Loading of Ascorbic Acid and Tocopherol in Eudragit-Nutriosomes to Counteract Intestinal Oxidative Stress

2019

The present study aimed at developing a new vesicular formulation capable of promoting the protective effect of ascorbic acid and tocopherol against intestinal oxidative stress damage, and their efficacy in intestinal wound healing upon oral administration. A pH-dependent copolymer (Eudragit&reg

3003AntioxidantVitamina CVitamina Emedicine.medical_treatmentNeuroimmunologyPhospholipidPharmaceutical Sciencelcsh:RS1-441CicatritzacióWound healingNutriose02 engineering and technologymedicine.disease_causeEudragitArticlelcsh:Pharmacy and materia medica03 medical and health scienceschemistry.chemical_compoundOral administrationmedicinePhospholipid vesiclesVitamin ETocopherolVitamin C030304 developmental biology0303 health sciencesIntestinsChromatographyVesiclePrebiotic021001 nanoscience & nanotechnologyAscorbic acidIntestinal wound healingNeuroimmunologiaIntestineschemistryAntioxidant; Eudragit; Intestinal wound healing; Nutriose; Phospholipid vesicles; 3003Antioxidant0210 nano-technologyOxidative stress
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Development of novel diolein–niosomes for cutaneous delivery of tretinoin: Influence of formulation and in vitro assessment

2014

Abstract This work describes innovative niosomes, composed of diolein alone or in association with the hydrophilic penetration enhancer Labrasol ® , as carriers for cutaneous drug delivery. The model drug was tretinoin and conventional, and Labrasol ® containing liposomes was used as controls to evaluate the influence of vesicle composition and the role of Labrasol ® on vesicle physico-chemical properties and performance as skin delivery system. Vesicles, prepared by the thin film hydration technique, were characterized in terms of size distribution, morphology, zeta potential, structure, incorporation efficiency, and rheological properties. The influence of carrier composition on tretinoin…

KeratinocytesSurface PropertiesDrug CompoundingSkin AbsorptionPharmaceutical ScienceTretinoinHuman skinNanotechnologyIn Vitro TechniquesAdministration CutaneousGlyceridesDiglyceridesX-Ray DiffractionStratum corneummedicineZeta potentialHumansNiosomeParticle SizeCells CulturedSkinDrug CarriersLiposomeMicroscopy ConfocalChemistryBilayerVesicleEndocytosismedicine.anatomical_structureLiposomesDrug deliveryBiophysicsRheologyInternational Journal of Pharmaceutics
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