Search results for "testing."

Design Procedures for Soil-Lime Stabilization for Road and Railway Embankments. Part 2-Experimental Validation

2012

AbstractAs detailed in Part 1, the most common Italian Technical Specifications refer to different design methodologies for design of lime-soil mixtures, some being quite different from those internationally adopted. Therefore, it seemed appropriate to the Authors to compare these methodologies, via a wide experimental program.It is shown that the Italian methodology of the National Road Agency is different not only from those used in Italy, but also from the main international standards. The experimental results highlight that a revision of that methodology is needed in order to bring it into line with what is prescribed by the European standard.

Multiphysical Testing of Soils and Shales. Springer, 978-3-642-32491-8, Springer Series in Geomechanics and Geoengineering, 340p.

2012

Advances in Laboratory Testing and Modelling of Soils and Shales (ATMSS).

2017

This volume contains the invited keynote and feature lectures, as well as the papers that have been presented at the workshop. The topics of the lectures and papers cover a wide range of theoretical and experimental research, including unsaturated behaviour of soils and shales, multiphysical testing of geomaterials, hydromechanical behaviour of shales and stiff clays, the geomechanical behaviour of the Opalinus Clay shale, advanced laboratory testing for site characterization and in situ applications, and soil–structure interactions.

Sexually transmitted COVID‐19

2020

Subclinical impairment of lung function is related to mild cardiac dysfunction and manifest heart failure in the general population.

2016

Lung function impairment has previously been related to heart failure, although no overt cardiovascular or structural heart disease is present. The extent to which pulmonary function is related to subclinical left ventricular impairment in the general population remains to be investigated.15010 individuals from the general population (mean age 55±11years, 50.5% men) in the Gutenberg Health Study underwent spirometry, transthoracic echocardiography and biomarker measurement. Forced expiratory volume in 1s (FEV1) and forced vital capacity (FVC) in percent of the predicted value and FEV1/FVC ratio were associated with echocardiographic measures of cardiac structure, systolic and diastolic func…

Cardiorespiratory fitness in volleyball athletes following a covid-19 infection: A cross-sectional study

2021

Athletes’ lifestyles have been dramatically affected by the coronavirus disease 2019 (COVID-19) pandemic. Since COVID-19 primarily affects the respiratory system and to a lesser degree the cardiovascular system, the goal of this study was to examine the effects of COVID-19-caused detraining on cardiorespiratory fitness (CRF) of recently recovered volleyball athletes. Sixteen experienced volleyball athletes (age 24 ± 4.5 years) who were recently diagnosed and recovered from a COVID-19 infection volunteered to participate in this study and were tested for CRF and spirometry. Given that participants had only mild symptoms of infection, the primary focus of this study was on the effects of detr…

Italian pediatric respiratory society recommendations on pediatric pulmonary function testing during COVID-19 pandemic

2020

The coronavirus disease 2019 (COVID-19) is a public health emergency of international concern caused by a newly discovered coronavirus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2). Person-toperson transmission of SARS-CoV-2 occurs primarily through close contact with an infected person, mainly occurring via respiratory droplets and after touching contaminated objects. Accordingly, pulmonary function testing (PFT) could be considered at high-risk for viral transmission due to the potential for coughing and droplet formation during PFT procedures. The most likely surfaces for possible contamination by this route are mouthpieces, proximal valves, and tubing. Also, both technic…

Genome-wide association analysis identifies six new loci associated with forced vital capacity

2014

Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung diseases. We performed genome-wide association study meta-analysis of FVC in 52,253 individuals from 26 studies and followed up the top associations in 32,917 additional individuals of European ancestry. We found six new regions associated at genome-wide significance (P <5 x 10(-8)) with FVC in or near EFEMP1, BMP6, MIR129-2-HSD17B12, PRDM11, WWOX and KCNJ2. Two loci previously associated with spirometric measures (GSTCD and PTCH1) were related to FVC. Newly implicated regions were followed up in samples from African-American, Korean, Chinese and Hispani…

Respiratory Effects of Exposure to Traffic-Related Air Pollutants During Exercise

2020

Traffic-related air pollution (TRAP) is increasing worldwide. Habitual physical activity is known to prevent cardiorespiratory diseases and mortality, but whether exposure to TRAP during exercise affects respiratory health is still uncertain. Exercise causes inflammatory changes in the airways, and its interaction with the effects of TRAP or ozone might be detrimental, for both athletes exercising outdoor and urban active commuters. In this Mini-Review, we summarize the literature on the effects of exposure to TRAP and/or ozone during exercise on lung function, respiratory symptoms, performance, and biomarkers. Ozone negatively affected pulmonary function after exercise, especially after co…

Clinical and economic consequences of switching from omalizumab to mepolizumab in uncontrolled severe eosinophilic asthma

2021

AbstractSevere asthma is burdened by frequent exacerbations and use of oral corticosteroids (OCS), which worsen patients’ health and increase healthcare spending. The aim of this study was to assess the clinical and economic impact of switching from omalizumab (OMA) to mepolizumab (MEP) in patients eligible for both biologics, but not optimally controlled by omalizumab. We retrospectively enrolled uncontrolled severe asthmatic patients who switched from OMA to MEP during the last two years. Information included blood eosinophil count, asthma control test (ACT), spirometry, serum IgE, fractional exhaled nitric oxide (FeNO), OCS intake, drugs, exacerbations/hospitalizations, visits and diagno…