Search results for "testing."
showing 10 items of 1654 documents
Psychodiagnostic Assessment of Pathological Gamblers: A Focus on Personality Disorders, Clinical Syndromes and Alexithymia
2015
Comorbid psychopathological syndromes are common in pathological gamblers (PGs), but the contribution of alexithymia, as a disorder of affect regulation, has not been fully explored yet. This study sought to examine the association between personality disorders, clinical syndromes and alexithymia levels in a group of PGs and to highlight a relationship between gambling behaviour and alexithymia scores, apart from the relationship between other disorders and gambling behaviour. Psychological assessment included the South Oaks Gambling Screen, Millon Clinical Multiaxial Inventory (MCMI-III) and Toronto Alexithymia Scale (TAS-20) performed on 70 treatment seeking PGs and 70 healthy controls. S…
Stubborn sets, frozen actions, and fair testing
2021
Many partial order methods use some special condition for ensuring that the analysis is not terminated prematurely. In the case of stubborn set methods for safety properties, implementation of the condition is usually based on recognizing the terminal strong components of the reduced state space and, if necessary, expanding the stubborn sets used in their roots. In an earlier study it was pointed out that if the system may execute a cycle consisting of only invisible actions and that cycle is concurrent with the rest of the system in a non-obvious way, then the method may be fooled to construct all states of the full parallel composition. This problem is solved in this study by a method tha…
Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing.
2014
In genetic toxicology, risk assessment has traditionally adopted linear dose-responses for any compound that causes genotoxic effects. Increasing evidence of non-linear dose-responses, however, suggests potential cellular tolerance to low levels of many genotoxicants with diverse modes of action. Such putative non-linear dose-responses need to be substantiated by strong mechanistic data that identifies the mechanisms responsible for the tolerance to low doses. This can be achieved by experimental demonstration of cytoprotective mechanisms and by providing experimental support for the existence of tolerance mechanisms against low dose effects. By highlighting key experiments into low dose me…
Asthma, allergies and respiratory symptoms in different activity groups of swimmers exercising in swimming halls
2021
Abstract Background Respiratory symptoms are common in competitive swimmers. However, among these and in swimmers at other activity levels the swimming distance, the total spent time in swimming halls and their medical background varies. Our objectives were, first, to assess their medical histories and the associations with respiratory symptoms among swimmers in different activity groups and then second, to study the pulmonary function findings and related medications in competitive swimmers who exercise in swimming hall environments the most. Methods First, 1118 participants consisting of 133 competitive-, 734 fitness- and 251 occasional swimmers answered questionnaires concerning their me…
Relationship between particle size and dissolution rate of bulk powders and sieving characterized fractions of two qualities of orthoboric acid
1996
Drug Dev. Ind. Pharm. ISI Document Delivery No.: VN279 Times Cited: 1 Cited Reference Count: 22 Tromelin, A Habillon, S Andres, C Pourcelot, Y Chaillot, B; International audience; We have carried out a study of the particle size distribution and aqueous dissolution rate of two commercially available qualities of orthoboric acid, labeled ''crystal'' (ABC) and ''powder'' (ABP). In a previous work, we have shown that the two commercial qualities of orthoboric acid chosen as model compound (''powder'' and ''crystal'') are related to the same crystal network in spite of their different names. However, these two qualities have very different size particle distributions, as previously determined b…
Assessing behavioural problems and assets in children and adolescents
1990
Abstract The main purpose of this brief report is to introduce a wide range battery of instruments for the psychological assessment of children and adolescents, which was developed in Spain and coordinated by the last author. The battery includes a General Diagnostic Report (anamnesis and general way of life), two Behaviour Problem Scales (one for school and one for non-school settings), a Hyperactivity Scale, the ‘Battery of Socialization’, the I-6 (Junior) Questionnaire, the EPQ-J, a Questionnaire for the Assessment of Self-Concept, the Antisocial Behaviour Scale, a Locus of Control Scale, an Irrational Beliefs Inventory, an Assertiveness Scale, a Fear Inventory, an Anxiety Scale, a Depre…
Automated GUI Testing for Android Applications
2012
Mobiililaitteet ovat yhä tärkeämmässä asemassa yhteiskunnassamme. Kun mobiililaitteiden käyttäjien määrä kasvaa, samoin kasvaa tarve sovelluksien paremmalle laadunvarmistukselle. Testauksen automatisointi on yksi avaintekijöistä sovelluksien laadun parantamiseen. Tämä tutkimus on kirjallisuuskatsaus Android-ohjelmien graafisten käyttöliittymien testauksen automatisaation nykytutkimuksesta. Mobile devices are becoming more and more important in our society. As the number of mobile device users grows, so does the importance of proper application quality control and verification. Test automation is one of the key factors in increasing application quality. This paper is a literature review on c…
Intralaboratory validation of four in vitro assays for the prediction of the skin sensitizing potential of chemicals
2011
Abstract Allergic contact dermatitis is induced by repeated skin contact with an allergen. Assessment of the skin sensitizing potential of chemicals, agrochemicals, and especially cosmetic ingredients is currently performed with the use of animals. Animal welfare and EU legislation demand animal-free alternatives reflected in a testing and marketing ban for cosmetic ingredients beginning in 2013. The underlying mechanisms of induction and elicitation of skin sensitization are complex and a chemical needs to comply several properties being skin sensitizing. To account for the multitude of events in the induction of skin sensitization an in vitro test system will consist of a battery of vario…
Molecular Strategies for Targeting Antioxidants to Mitochondria: Therapeutic Implications
2015
Mitochondrial function and specifically its implication in cellular redox/oxidative balance is fundamental in controlling the life and death of cells, and has been implicated in a wide range of human pathologies. In this context, mitochondrial therapeutics, particularly those involving mitochondria-targeted antioxidants, have attracted increasing interest as potentially effective therapies for several human diseases. For the past 10 years, great progress has been made in the development and functional testing of molecules that specifically target mitochondria, and there has been special focus on compounds with antioxidant properties. In this review, we will discuss several such strategies, …
Delivery of liquorice extract by liposomes and hyalurosomes to protect the skin against oxidative stress injuries.
2015
Liquorice extract, obtained by percolation in ethanol of Glycyrrhiza glabra L. roots, was incorporated in liposomes and hyalurosomes, new phospholipid-sodium hyaluronate vesicles, and their protective effect against oxidative stress skin damages was probed. As a comparison, raw glycyrrhizin was also tested. All the vesicles were small in size (≤ 100 nm), with a highly negative zeta potential ensuring long-term stability, and able to incorporate a high amount of the extract. In vitro tests showed that the liquorice extract loaded in vesicles was able to scavenge DPPH free radical (80% inhibition) and to protect 3T3 fibroblasts against H2O2-induced oxidative stress, restoring the normal condi…