Search results for "testing"

Lynch Syndrome Genetics and Clinical Implications

2023

Lynch syndrome (LS) is one of the most prevalent hereditary cancer syndromes in humans and accounts for some 3% of unselected patients with colorectal or endometrial cancer and 10%-15% of those with DNA mismatch repair-deficient tumors. Previous studies have established the genetic basis of LS predisposition, but there have been significant advances recently in the understanding of the molecular pathogenesis of LS tumors, which has important implications in clinical management. At the same time, immunotherapy has revolu-tionized the treatment of advanced cancers with DNA mismatch repair defects. We aim to review the recent prog-ress in the LS field and discuss how the accumulating epidemiol…

Bayesian hypothesis testing: A reference approach

2002

Summary For any probability model M={p(x|θ, ω), θeΘ, ωeΩ} assumed to describe the probabilistic behaviour of data xeX, it is argued that testing whether or not the available data are compatible with the hypothesis H0={θ=θ0} is best considered as a formal decision problem on whether to use (a0), or not to use (a0), the simpler probability model (or null model) M0={p(x|θ0, ω), ωeΩ}, where the loss difference L(a0, θ, ω) –L(a0, θ, ω) is proportional to the amount of information δ(θ0, ω), which would be lost if the simplified model M0 were used as a proxy for the assumed model M. For any prior distribution π(θ, ω), the appropriate normative solution is obtained by rejecting the null model M0 wh…

Quantum Query Complexity of Boolean Functions with Small On-Sets

2008

The main objective of this paper is to show that the quantum query complexity Q(f) of an N-bit Boolean function f is bounded by a function of a simple and natural parameter, i.e., M = |{x|f(x) = 1}| or the size of f's on-set. We prove that: (i) For $poly(N)\le M\le 2^{N^d}$ for some constant 0 < d < 1, the upper bound of Q(f) is $O(\sqrt{N\log M / \log N})$. This bound is tight, namely there is a Boolean function f such that $Q(f) = \Omega(\sqrt{N\log M / \log N})$. (ii) For the same range of M, the (also tight) lower bound of Q(f) is $\Omega(\sqrt{N})$. (iii) The average value of Q(f) is bounded from above and below by $Q(f) = O(\log M +\sqrt{N})$ and $Q(f) = \Omega (\log M/\log N+ \sqrt{N…

Impact Force Identification and Location on Isotropic and Composite Panels.

2009

Influence of Background Knowledge and Language Proficiency on Comprehension of Domain-Specific Texts by University Students

2019

This paper presents the results of a quantitative study that explores two factors contributing to reading comprehension of domain specific texts, namely level of language proficiency and background knowledge. Overall, 32 students participated in the study by taking two custom-designed reading comprehension tests. The test scores were further  analyzed using SPSS statistical software. The results of statistical tests revealed the differences between study groups as well as the effects of compensation. More precisely, the most proficient group scored higher on almost all tests and completed the tests more quickly than the remaining groups. The statistical tools used to test the data showed th…

SAUCE: A web application for interactive teaching and learning of parallel programming

2017

Abstract Prevalent hardware trends towards parallel architectures and algorithms create a growing demand for graduate students familiar with the programming of concurrent software. However, learning parallel programming is challenging due to complex communication and memory access patterns as well as the avoidance of common pitfalls such as dead-locks and race conditions. Hence, the learning process has to be supported by adequate software solutions in order to enable future computer scientists and engineers to write robust and efficient code. This paper discusses a selection of well-known parallel algorithms based on C++11 threads, OpenMP, MPI, and CUDA that can be interactively embedded i…

A new approach to partial discharge detection under DC voltage

2018

The continuing development of HVDC power transmission systems presents many problems related to evaluation of the reliability of power system assets [1]-[5]. In this context the identification of insulation defects plays a key role in preventing unexpected failures of electrical components. Partial discharge (PD) measurement is a useful approach to assessing the condition of HV power apparatus and cables. Such measurements are also widely employed for HVAC systems. The inception mechanisms of PD in AC systems are well-known, and measurements are usually performed following the IEC 60270 standard [6]. PD measurements under DC voltage present complexities related to the nature of the phenomen…

Towards More Sustainable Pavement Management Practices Using Embedded Sensor Technologies

2019

Road agencies are constantly being placed in difficult situations when making road maintenance and rehabilitation decisions as a result of diminishing road budgets and mounting environmental concerns for any chosen strategies. This has led practitioners to seek out new alternative and innovative ways of monitoring road conditions and planning maintenance routines. This paper considers the use of innovative piezo-floating gate (PFG) sensors and conventional strain gauges to continuously monitor the pavement condition and subsequently trigger maintenance activities. These technologies can help develop optimized maintenance strategies as opposed to traditional ad-hoc approaches, which often le…

Recommendation of RILEM TC237-SIB on cohesion test of recycled asphalt

2018

This recommendation describes how to evaluate the presence of potentially active bitumen in recycled asphalt (RA) materials through the cohesion test. The experimental protocol is designed according to the research performed by the RILEM Technical Committee 237-SIB ‘‘Testing and characterization of sustainable innovative bituminous materials and systems’’ with the purpose, to develop a new, simple and fast method for the characterization of RA while limiting the need for conventional rheological tests. The guidelines in this recommendation focus on the testing procedure including specimen preparation, data analysis and provide information on the preparation of a tests report.

Structural performances of pultruded GFRP emergency structures – Part 2: Full-scale experimental testing

2019

Abstract This paper presents an experimental testing of a pultruded glass fiber reinforced polymer (FRP) structure used for emergency applications continuing the discussion presented in a previous paper (part 1) where the study of the characteristics of material and elements are presented. First, the design of the composite structure and components and the evaluation of the structural behavior by means of numerical and analytical approach according to current regulatory codes are described. In this frame, the global and local response was observed according to load paths deriving from the design loads at limit states. Then, the experimental test on a full-scale 2D model is presented at diff…