Search results for "testing"

showing 10 items of 1769 documents

Depression bei Kindern und Jugendlichen: Prävalenz, Diagnostik, ätiologische Faktoren, Geschlechtsunterschiede, therapeutische Ansätze

2007

Die Prävalenzraten für die verschiednen Formen von Depression (depressiven Stimmungen, depressiven Syndromen und Major Depression) haben in den letzten Jahren zugenommen, die Geschlechtsunterschiede mit deutlich höheren Raten für Mädchen haben sich erhöht. Als ätiologische Faktoren für das Auftreten von Depression werden u. a. zunehmende Stressfaktoren, dysfunktionale Bewältigungsstile, ein negatives Körperkonzept und unsichere Bindungsmuster genannt. Unter den verschiedenen therapeutischen Ansätzen hat sich die psychoananlytische Behandlungsmethode als die umfassendste erwiesen. Schlüsselwörter Prävalenzraten - Komorbidität - Stress - Coping - Körperkonzept - Bindung Prevalence rates of th…

Coping (psychology)medicine.medical_specialtyGeschlechtsunterschiedPsychologische MessungDepression (Emotion)EtiologyCross-sectional studyEpidemiologyKindDysfunctional familyHuman Sex DifferencesRisk FactorsEpidemiologyNegative body imageMajor DepressionmedicinePsychological testingPsychiatryGeschlechtsunterschiede beim MenschenEpidemiologieDepressive StimmungDepressionPsychological Assessmentmedicine.diseasePsychotherapieComorbidityPsychotherapyEtiologyJugendPsychologyClinical psychologyÄtiologiePsychologische Diagnostik
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Mutation Analysis of Core Binding Factor A1 in Patients with Cleidocranial Dysplasia

1999

SummaryCleidocranial dysplasia (CCD) is a dominantly inherited disorder characterized by patent fontanelles, wide cranial sutures, hypoplasia of clavicles, short stature, supernumerary teeth, and other skeletal anomalies. We recently demonstrated that mutations in the transcription factor CBFA1, on chromosome 6p21, are associated with CCD. We have now analyzed the CBFA1 gene in 42 unrelated patients with CCD. In 18 patients, mutations were detected in the coding region of the CBFA1 gene, including 8 frameshift, 2 nonsense, and 9 missense mutations, as well as 2 novel polymorphisms. A cluster of missense mutations at arginine 225 (R225) identifies this residue as crucial for CBFA1 function. …

Core binding factorRecombinant Fusion ProteinsDNA Mutational AnalysisGreen Fluorescent ProteinsMolecular Sequence DataMutation MissenseHuman malformation syndromeCore Binding Factor Alpha 1 SubunitBiologyTransfectionmedicine.disease_causeBone and BonesCleidocranial dysplasiaCell LineFrameshift mutationCBFA1GeneticsmedicineHumansMissense mutationGenetics(clinical)SupernumeraryFrameshift MutationGenetics (clinical)Sequence DeletionGeneticsMutationPolymorphism GeneticCleidocranial DysplasiaCore Binding FactorsArticlesmedicine.diseaseOsteochondrodysplasiaNeoplasm ProteinsRadiographyNuclear localizationLuminescent ProteinsPhenotypeMicroscopy FluorescenceMutation testingTranscription factorHaploinsufficiencyToothTranscription FactorsThe American Journal of Human Genetics
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Inference for the interclass correlation in familial data using small sample asymptotics

2012

Inference on the parent-offspring correlation coefficient is an important problem in the analysis of familial data, and point estimates and likelihood based inference are available in the literature. In this work, corrections for the signed log-likelihood ratio test statistics are proposed, based on small sample asymptotics, in order to achieve accurate small sample performance. The corrected statistic can be used for hypothesis testing as well as for interval estimation.

Correlation coefficientInterclass correlationInterval estimationStatisticsFiducial inferenceInferencePoint estimationStatisticMathematicsStatistical hypothesis testingAIP Conference Proceedings
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Familial hypercholesterolæmia in children and adolescents: Gaining decades of life by optimizing detection and treatment

2015

Contains fulltext : 155263.pdf (Publisher’s version ) (Open Access) Familial hypercholesterolaemia (FH) is a common genetic cause of premature coronary heart disease (CHD). Globally, one baby is born with FH every minute. If diagnosed and treated early in childhood, individuals with FH can have normal life expectancy. This consensus paper aims to improve awareness of the need for early detection and management of FH children. Familial hypercholesterolaemia is diagnosed either on phenotypic criteria, i.e. an elevated low-density lipoprotein cholesterol (LDL-C) level plus a family history of elevated LDL-C, premature coronary artery disease and/or genetic diagnosis, or positive genetic testin…

CounselingEuropean Atherosclerosis Society Consensus PanelPediatricsCardiac & Cardiovascular SystemsSTATIN THERAPYSettore MED/09 - Medicina InternaVascular damage Radboud Institute for Health Sciences [Radboudumc 16]Familial hypercholesterolemiaAdolescentsCarotid Intima-Media ThicknessINTIMA-MEDIA THICKNESSCost of IllnessPregnancyRisk FactorsDiagnosisYOUNG-ADULTSHIPERCOLESTEROLEMIA (DIAGNÓSTICO;TERAPIA;TENDÊNCIAS)Family historyYoung adultChildChildrenEvidence-Based Medicinemedicine.diagnostic_testHomozygoteMiddle AgedFamilial hypercholesterolæmia3. Good healthEconomics MedicalAdolescents; Children; Consensus statement; Diagnosis; Ezetimibe; Familial hypercholesterolæmia; LDL cholesterol; PCSK9 inhibitor; Statin; Treatment; Cardiology and Cardiovascular MedicineCARDIOVASCULAR-DISEASEConsensus statementLDL cholesterolFemalelipids (amino acids peptides and proteins)Cardiology and Cardiovascular MedicineFamilial hypercholesterolaemiaLife Sciences & BiomedicineDiagnosimedicine.drugAdultHeterozygotemedicine.medical_specialtyStatinAdolescentmedicine.drug_classPCSK9 inhibitorENDOTHELIAL FUNCTIONLOW-DENSITY-LIPOPROTEINReviewsCOST-EFFECTIVENESS ANALYSIS1102 Cardiovascular Medicine And HaematologyMedication AdherenceHyperlipoproteinemia Type IIYoung AdultLife ExpectancyEzetimibemedicineHumansCORONARY-HEART-DISEASEGenetic TestingGenetic testingPregnancyScience & TechnologyClinical Laboratory Techniquesbusiness.industryPreventionStatinAtherosclerosismedicine.diseaseEzetimibeDietASSOCIATION EXPERT PANELBLOOD-PRESSURE RESEARCHPregnancy ComplicationsTreatmentEarly DiagnosisIntima-media thicknessCardiovascular System & HematologyDietary SupplementsPhysical therapyCardiovascular System & Cardiologybusiness
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The energy dependence of Zweig-rule-violating couplings. A dynamical calculation of ϕ → ρπ

1978

It has been argued that the violation of the Zweig rule is strongly dependent on the kinematical region, especially that it should decrease for large timeliket (asymptotic planarity). We have calculated thet-dependence of the vertex ϕρπ with two different methods, the first one using partial-wave dispersion relations and unitarity and the second one based on FESR and duality. The decrease in the timelike region is confirmed by both calculations. In the spacelike region the energy dependence of the Zweig-rule-violating coupling depends on the method of continuation to off-shell values. We only find an energy dependence if the full amplitude πρ → K $$\bar K$$ is taken into account.

CouplingPhysicsAmplitudeUnitarityQuantum electrodynamicsDispersion relationPlanarity testingMathematical physicsVertex (geometry)Il Nuovo Cimento A
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Fatigue Crack Growth for Different Ratios of Bending to Torsion in AlCu4Mg1

2008

The paper contains the fatigue crack growth test results obtained under proportional bending with torsion in AlCu4Mg1 aluminium alloy [1]. Specimens with rectangular cross sections and dimensions: length l = 90 mm, height w = 10 mm and thickness g = 8 mm were tested [2]. Each specimen had an external unilateral notch with depth 2 mm and radius ρ = 0.2 mm. The tests were performed under the stress ratio R = −1. The notches in the specimens were cut with a milling cutter and their surfaces were polished after grinding. The tests were realized on a fatigue test stand MZGS-100 where the ratio of torsion moment to bending moment was \( M_T (t)/M_B (t) = tg\alpha = \sqrt 3 /3,1{\text{ }}and\sqrt …

Crack closureMaterials scienceStress ratiovisual_artBending momentAluminium alloyvisual_art.visual_art_mediumTorsion (mechanics)Fatigue testingParis' lawComposite material
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Construction, assembly and tests of the ATLAS electromagnetic barrel calorimeter

2006

The construction and assembly of the two half barrels of the ATLAS central electromagnetic calorimeter and their insertion into the barrel cryostat are described. The results of the qualification tests of the calorimeter before installation in the LHC ATLAS pit are given.

CryostatPhysicsNuclear and High Energy PhysicsLarge Hadron ColliderCalorimeter (particle physics)Physics::Instrumentation and Detectors010308 nuclear & particles physicsBarrel (horology)Mechanical engineeringCryogenics01 natural sciencesNuclear physicsElectromagnetic calorimetermedicine.anatomical_structureAtlas (anatomy)0103 physical sciencesQualification testing[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]medicinePhysics::Accelerator PhysicsHigh Energy Physics::ExperimentNuclear Experiment010306 general physicsInstrumentationParticle Physics - ExperimentNuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
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Guest-Host Systems of 1,3,5-Tristyrylbenzenes

2003

(E,E,E)-1,3,5-Tris(3,4,5-trimethoxystyryl)benzene (1a) forms monoclinic crystals of the space group P21/c. Incorporation of three transoid diacetyl guest molecules between the three arms leads to triclinic crystals of the space group P1. The styryl groups, originally present in a nonsymmetrical conformation, are simultaneously transformed to a C3 arrangement. (E,E,E)-1,3,5-Tris- (3,4,5-tripropoxystyryl)benzene (1b) forms monoclinic crystals of the space group P21/c. The C3 arrangement of the styryl groups is present in the first, the unsymmetrical arrangement in the second modification. Incorporation of two acetone guests in the largest and the middle-sized angle space between the styryl ar…

Crystallographychemistry.chemical_compoundMaterials scienceGuest hostchemistryGroup (periodic table)MoleculeGeneral ChemistryTriclinic crystal systemSpace (mathematics)BenzenePlanarity testingMonoclinic crystal systemZeitschrift für Naturforschung B
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On real-time algorithms for the location search of discontinuous conductivities with one measurement

2008

We discuss, and compare, two simple methods that provide coordinates of a point in the vicinity of one inclusion within some object with homogeneous electrical properties. In the context of nondestructive testing such an inclusion may correspond to a material defect, whereas in medicine this may correspond to a lesion in the brain, to name only two possible applications. Both methods use only one pair of voltage/current measurements on the entire boundary of the object to determine a single pair of coordinates that is considered to be close to the center of the inclusion. The first method has been proposed previously by Kwon, Seo and Yoon; the second method, called here the effective dipole…

Current (mathematics)business.industryApplied MathematicsBoundary (topology)Context (language use)Inverse problemComputer Science ApplicationsTheoretical Computer ScienceDipoleSimple (abstract algebra)Nondestructive testingSignal ProcessingPoint (geometry)businessAlgorithmMathematical PhysicsMathematicsInverse Problems
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Effect of cyclic loading on fracture strength and microleakage of a quartz fiber dowel with different adhesive, cement and resin core material combin…

2010

Background: This study evaluated the performance of different adhesive-cement-core combinations coupled with quartz fiber dowels after cyclic loading and fracture strength tests and assessed the microleakage using dye penetration method. Methods: Forty maxillary canines (n=10 per group) were restored with fiber dowels (Quartz fiber DT Light Post) and four adhesive-cement-core material combinations [(Group 1: All-Bond 2+C&B (root) / All-Bond 2+Biscore (core); Group 2: All-Bond 2+Bisfil 2B (root) / All-Bond 2+Bisfil 2B (core); Group 3: Scotchbond 1+RelyX ARC (root) / Scotchbond 1+Supreme (core); Group 4: RelyX Unicem (root) / Scotchbond 1+Filtek Supreme (core)]. The specimens were initially c…

CuspidDental CementsEquipment DesignQuartzCyclic loading Fiber dowels Fracture strength MicroleakageComposite ResinsPermeabilityPolyethylene GlycolsResin CementsWeight-BearingResins SyntheticPolymethacrylic AcidsSettore MED/28 - Malattie OdontostomatologicheDentin-Bonding AgentsMaterials TestingMethacrylatesBisphenol A-Glycidyl MethacrylateEquipment FailureStress MechanicalPost and Core Technique
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