Search results for "testing"
showing 10 items of 1769 documents
14th International HLA and Immunogenetics Workshop: Report on the Prospective Chronic Rejection Project
2007
An international collaborative study of 45 transplant centers was undertaken at the 14th International HLA (human leukocyte antigen) and Immunogenetics Workshop to see if HLA antibodies detected posttransplant are predictive of chronic graft failure. With the newly developed assay, MICA (major histocompatibility complex class I-related chain A) antibodies were also measured and their effect analyzed. Total of 5219 sera from patients who were more than 6 months posttransplant with functioning graft were tested for HLA antibodies by enzyme-linked immunosorbent assay, flow cytometry, or Luminex. HLA antibodies were found in 27.2% of kidney patients, 23.6% in the liver, 52.7% in the heart, and …
Exploiting multivalent nanoparticles for the supramolecular functionalization of graphene with a nonplanar recognition motif.
2013
The supramolecular modification of planar graphene with the geometri- cally mismatched, curved 9,10-di(1,3-dithiole-2-ylidene)-9,10-dihydroanthracene (exTTF) molecule is demonstrated. The exTTF-graphene interaction is governed by p-p and CH-p interactions, with a negligible contribution from charge transfer. We amplified these weak forces through multivalent gold nanoparticles. Our re- sults show that planarity is not a prerequisite for recognition motifs for graphene.
European vestibular experiments on the Spacelab-1 mission: 2. Experimental equipment and methods
1986
A series of vestibular experiments were performed in conjunction with the first Spacelab mission, consisting of sets of pre-, in- and postflight tests. A multipurpose experimental apparatus used for the diverse flight and ground tests is presented. Additional apparatus together with the multi-purpose package were used in the baseline data collection facility at the landing site at NASA Dryden Flight Research Facility for the ground tests. The tests involved optokinetic, caloric and mechanical (whole-body or head-alone) stimulation. The latter included linear acceleration in the subject's x, y and z axes, static roll and yaw about an earth-vertical axis. Physiological parameters such as elec…
Improved global-local model to predict guided-wave scattering patterns from discontinuities in complex parts
2019
Ultrasonic guided-wave testing can greatly benefit from (1) an ability to provide quantitative information on the damage that is being detected, and (2) an ability to select the best mode-frequency combination for maximum sensitivity to a given type of damage. Achieving these capabilities in complex structures (e.g. nonprismatic structures such as a stiffened panel in aerospace fuselages) is a nontrivial task. This paper will discuss an improved Global-Local (GL) method where the geometrical “local” discontinuity (e.g. the stiffener) is modelled by traditional FE discretization and the rest of the structure (“global” part) is modelled by Semi-Analytical Finite Element (SAFE) cross-sectional…
Coded Excitation of the Fundamental Flexural Guided Wave in Coated Bone Phantoms
2017
There is an increasing interest of using ultrasonic guided waves to assess long cortical bones. In particular, a method of ultrasonic estimation of cortical thickness based on the fundamental flexural guided wave (FFGW), generally consistent with the A0 Lamb mode, has proven to be promising in vitro and modeling studies. Soft-tissue coating on top of the bone makes, however, the related in vivo application challenge. Visibility of FFGW on top of the soft tissue is not good due to the characteristic displacement profile of this mode, and due to its relatively high attenuation in the bone and surrounding tissue. Moreover, the soft tissue provides a direct propagation path for ultrasonic modes…
Obstructing propagation of interfering modes improves detection of guided waves in coated bone models
2014
Interference due to wave propagation in soft tissue that covers the bone is a major challenge to in vivo assessment of the fundamental flexural guided wave (FFGW) in bone. To improve signal-to-interference ratio (SIR) we propose to obstruct the propagation of interfering modes by locally deforming the coating by external mechanical compression. This approach was modeled by 2D finite-element transient domain (FEMTD) simulations in a fluid-coated (7 mm) solid plate (3 mm). The fluid layer mimics the soft tissue that covers the bone. A single emitter or a 6-element phased array excited ultrasound pulses at 50 kHz on the surface of the coating, and a receiver array was placed on the surface, 20…
2D Waveguided Bessel Beam Generated Using Integrated Metasurface-Based Plasmonic Axicon.
2020
International audience; Near-field imaging of the propagation of a diffraction-free Bessel-type beam in a guided wave configuration generated by means of a metasurface-based axicon lens integrated on a silicon waveguide is reported. The operation of the axicon lens with a footprint as small as 11 μm2 is based on local engineering of the effective index of the silicon waveguide with plasmonic nanoresonators. This generic approach, which can be adapted to different types of planar lightwave circuit platforms, offers the possibility to design nano-engineered optical devicesbased on the use of plasmonic resonators to control light at the nanoscale.
Global–local model for three-dimensional guided wave scattering with application to rail flaw detection
2021
This study presents a three-dimensional global–local formulation for the prediction of guided wave scattering from discontinuities (e.g. defects). The approach chosen utilizes the Semi-Analytical Finite Element method for the “global” portion of the waveguide, and a full Finite Element discretization for the “local” portion of the waveguide containing the discontinuity. The application of interest is the study of guided wave scattering from transverse head defects in rails. Theoretical scattering results are impossible to obtain in this case for a wide-frequency range. While three-dimensional Semi-Analytical Finite Element–Finite Element models for guided wave scattering studies have been …
Detection of disbonds in multilayer structures by laser-based ultrasonic technique
2008
Adhesively bonded multi-layer structures are frequently used, mostly in the aerospace industry, for their structural efficiency. Nondestructive evaluation of bond integrity in these types of structures, both after manufacturing and for periodic inspection during service, is extremely important. A laser-based ultrasonic technique has been evaluated for non-contact detection of disbonds in aluminum multi-layer structures. Two configurations have been used to detect disbonded areas: pitch-catch with unidirectional guided wave scan and through-transmission with bidirectional scan. Guided wave scanning was done with a laser line source and air-coupled transducer sensing at 500 kHz, 1 ;MHz, and 2…
Empfindlichkeitsprüfung vonCandidaSpecies unterAnwendung des kommerziellen Agardiffusionsverfahrens mit LD 2-Ringen für die Routinediagnostik
2003
Zusammenfassung: Die steigende Zahl von Pilzinfektionen, die Entwicklung und Einfuhrung neuer antimykotischer Substanzen sowie die Moglichkeit der Resistenzentwicklung unter Therapie mit Antimykotika haben in der Vergangenheit zu einem standig wachsenden Bedarf an standardisierten Verfahren zur Empfindlichkeitstestung von pathogenen Pilzen gefuhrt. Hierbei entstand unter anderem eine Vielzahl kommerzieller Testverfahren, bei denen mit Hilfe vorgefertigter Testkits eine einfache und schnelle Durchfuhrung der Empfindlichkeitsprufung erzielt werden soll. Eine dieser Methoden, welche in manchen Laboratorien in Deutschland angewendet wird, ist das so genannte LD 2 Ring-Verfahren, welches auf dem…