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showing 10 items of 311 documents

Inguinal Hernia: Defect Obliteration with the 3D Dynamic Regenerative Scaffold Proflor™.

2021

Prosthetic inguinal hernia repair presents significant challenges. Some of these, such as mesh fixation and quality of the biologic response, are still debated among surgeons. For example, there is no strong consensus regarding a specific condition that characterizes the surgical procedure during herniorrhaphy. This issue concerns management of the hernia defect, which in conventional hernia repair with flat meshes remains patent. However, a critical analysis of typical postoperative complications after inguinal hernia repair reveals that some of these adverse events are related to patency of the hernial opening. Postoperative discomfort, pain with specific movements and even hernia recurre…

Scaffoldmedicine.medical_specialtyPain PostoperativeBiologic responsebusiness.industrymedicine.medical_treatmentProcedural approachHernia InguinalGeneral MedicineProstheses and ImplantsSurgical Meshmedicine.diseaseHernia repairGroinSurgeryMesh fixationInguinal herniaRecurrenceHernial openingmedicineHumansHerniabusinessHerniorrhaphySurgical technology international
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Metilazione del DNA in artrite reumatoide

2005

Lo stato di metilazione del DNA genomico e del gene PTHrP è stato valutato con tecniche molecolari e citogenetiche in artrite reumatoide (AR), patologia autoimmune caratterizzata anche da alta incidenza di linfomi e da ipercalcemia per overespressione del gene PTHrP. La metilazione del DNA, infatti, ha un ruolo critico nello sviluppo delle malattie neoplastiche; il gene PTHrP avendo tre promotori uno dei quali contiene un’isola CpG è un buon candidato per la deregolazione da alterato pattern di metilazione locale. Le indagini sulla metilazione genomica, condotte su DNA estratto da sangue periferico di pazienti e di donatori e amplificato in reazioni di Methylation-Sensitive Arbitrarily Prim…

Settore BIO/18 - Geneticainstead chromosomes of controls were almost uniformly decorated by brilliant grains. Studies on methylation of PTHrP gene promoter 2 performed on five CpG island internal sites using the Methylation-Sensitive Restriction Endonuclease Multiplex (MSREM)-PCR showed that one of the sites nearest the trascription starting point is heavy methylated in a significantly high number of RA patients. Thus RA seems to be characterized by genomewide hypomethylation associated with local hypermethylation like the most part of tumors. This result raises the possibility that susceptibility to lymphomas is related to abnormal DNA methylation levels and suggests the opportunity to evaluate the DNA methylation status in RA patientin fact the demethylating therapies together with diet and life style can act towards an increase of tumor risk. Future studies using a larger number of subjects could confirm these findings.Rheumatoid Arthritis (RA) is a chronic multisystem inflammatory disease characterized by high recurrence of lymphomas as well as hypercalcemia due to PTHrP overexpression. Because of DNA methylation plays a critical role in development of neoplasias we determined in RA patients the global DNA methylation status and local methylation pattern of the CpG island of one of the three promoters of PTHrP gene utilizing molecular and cytogenetic techniques. Investigations performed on DNA from peripheral blood of patients and donors amplified by Methylation-Sensitive Arbitrarily Primed (MeS-AP)-PCR indicated that RA is strongly associated with global DNA hypomethylation. Similarly chromosomal DNA methylation pattern analysis by indirect immunofluorescence technique with anti 5-methylcitosine antibody showed all peripheral lymphocyte metaphases from RA patients with chromosomes weakly fluorescent without discrete grain
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Selective heterogeneous photocatalysis: examples of green photosyntheses

2009

Settore CHIM/07 - Fondamenti Chimici Delle TecnologiePhotocatalysis green photosyntheses
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Selective Gree-Syntheses of Flavour-Molecules through TiO2 Photocatalysis in Aqueous Suspension

2013

Settore CHIM/07 - Fondamenti Chimici Delle TecnologieSelective Gree-Syntheses TiO2 Photocatalysis Aqueous Suspension
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La città di Alphabet. Architettura per prosumers.

2021

Attraverso alcuni aspetti salienti dell’ideazione, della produzione e dell’opposizione al progetto del Toronto Quayside di Sidewalk labs, l’articolo discute l’influenza delle infrastrutture digitali per l’informazione sul progetto della casa e del quartiere. L’ampliamento delle attività svolte da remoto nello spazio domestico, enfatizzato dal quotidiano della pandemia da Covid 19, costituisce per gli oligopolisti planetari degli urban data come Alphabet un utile volano pubblicitario e un acceleratore. La fusione dei nuovi vessilli della tecnoemancipazione e della sostenibilità in ipotesi sperimentali che mirano a costruirsi sia per intero che per parti realizza un nuovo orizzonte in cui lo …

Settore ICAR/14 - Composizione Architettonica E UrbanaTaking into account some salient aspects of the conception production and opposition to the Toronto Quayside project by Sidewalk labs the article discusses the influence of urban data-digital infrastructures on the architectural design of the house and the neighbourhood. The extension of remote control on the practices of everyday life in the domestic space emphasized by the daily Covid 19 pandemic constitutes a useful advertising reference and an accelerator for the planetary oligopolists of urban data such as Alphabet. The fusion of the new emblems of techno-emancipation and sustainability in experimental hypotheses that can be built both in whole or in parts draws a new horizon in which the domestic space generates a technological profit and the inhabitants are transformed into producers. From a historical perspective our reality eclipses the idea of technology as an anonymous contribution to collective progress demonstrated by Giedion in Mechanization takes command and subverts the allegorical value assigned by the Architecture of the Seventies to the relational utopias of the Web Stem and Cluster.
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Sine cura. Verso il ri-ciclo dell'architettura del secondo Novecento

2019

Gli argomenti discussi nel saggio interrogano il destino che il Codice dei Beni Culturali (2004- 2011) determina per le opere del secondo Novecento. Nella costruzione del futuro di questi manufatti, che per funzione, tecnologia e cicli d’uso sono spesso segnati dall’obsolescenza e dall’abbandono, le ambiguità e le incongruenze delle attuali procedure legislative sollecitano profondamente il ruolo culturale delle esperienze di ricerca che usano metodologie meta progettuali. Il confronto fra alcuni casi italiani ed altri europei rimarca il ruolo del progetto nella costruzione di una prospettiva di tutela trasformativa per il costruito del secondo Novecento. Nel quadro di azione marcato dall’o…

Settore ICAR/14 - Composizione Architettonica E UrbanaThe essay questions the future's possibilities to operate on the buildings of the second half of the twentieth century according to the Italian Code of Cultural Heritage (2004-2011). When arguing how to encourage the re-use of these artifacts which are often marked by short-life technology cycles obsolescence and abandonment the ambiguities and inconsistencies of current legislative procedures deeply stress the cultural role of research experiences that use project-oriented methodologies. The comparison between some Italian and other European cases highlights the role of a design approach in the construction of a transformative protection perspective for the built matter of the second half of the twentieth century. In a framework aiming to encourage a reconciliation between the recent built environment and the new paradigms of sustainability and circular economy architecture must recognize re-cycle practices as a main theoretical and procedural node. To modernize the late Modern built environment with contemporary construction components is not simply a matter of technical knowledge and expertise: but a theme with theoretical density aesthetic and ethical values. The architectural project in this field today must ask for greater congruence between the bureaucratic and administrative levels and the real consistency of this corpus. It is a matter of identifying strategies to equip it with capabilities meanings and contents remembering that demolition wastes have unsustainable environmental costs and uncertain results concerning the necessary new attribution of political and semantic meaning that these places await.
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La ricostruzione dell'abside in alcuni esempi della seconda metà del XVI secolo a Palermo

2015

Il contributo ha l’obiettivo di studiare alcuni casi di ricostruzione dell’abside eseguiti in edifici chiesastici palermitani nella seconda metà del XVI secolo. Si tratta delle chiese di San Sebastiano, San Francesco d’Assisi e San Martino delle Scale (all’interno dell’omonima abbazia), in cui, nella seconda metà del Cinquecento, per motivi liturgici, l’abside originaria viene “trasformata”, in un’abside “piatta”, al fine di potervi inserire il Coro ligneo. Il nuovo posizionamento del Coro, in conseguenza della Riforma tridentina - problematica centrale nell’Europa di età moderna – suscita, anche in questi casi palermitani, dibattiti e controversie. Il cambiamento della forma dell’abside de…

Settore ICAR/18 - Storia Dell'ArchitetturaThe paper aims to study some cases of reconstruction of the apse in some churches of Palermo in the second half of the 16th century. These are the churches of St. Sebastiano St. Francesco d’Assisi and St. Martino delle Scale (in the homonymous monastery) in wichfor liturgical reasons the original apse was "transformed" in a "flat" apse to insert in it the wooden choir. The new positioning of the choir after the Tridentine Reform was a central issue in the Europe of the modern age so even in Palermo there were some debates and controversies about this problem. The change of the shape of the apse determined in fact some considerable constructive problems related to its coverage.
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Palermo si cura. Pratiche culturali di mutuo soccorso come risposta alle fragilità della città (post)pandemica

2023

In un quadro di riferimento in cui la crisi è globalizzata ma diseguale e in mancanza di un sistema di welfare capace di rispondere alle urgenze dei contesti e dei gruppi sociali più marginalizzati, una risposta ai nuovi bisogni sociali ed individuali è stata offerta da reti solidali e da pratiche di mobilitazione dal basso che svolgono un ruolo di agency territoriale, spesso indipendentemente o in assenza di Istituzioni. Nel contesto palermitano un impegno agito da una pluralità di soggetti culturali già attivi sul territorio, riuniti in un’assemblea pubblica (Palermo si cura), durante il periodo del primo lockdown hanno dato vita ad azioni di mutuo soccorso per rispondere all’emergenza ec…

Settore ICAR/21 - UrbanisticaIn a framework in which the crisis is globalized but unequal and in the absence of a welfare system capable of responding to the urgencies of the most marginalized contexts and social groups a response to the new social and individual needs has been offered by networks of solidarity and from bottom-up mobilization practices that play a role of territorial agency often independently or in the absence of institutions. In the Palermo context a commitment made by a plurality of cultural subjects already active in the area gathered in a public assembly (Palermo si cura) during the period of the first lockdown gave rise to mutual aid actions to respond to the economic emergency and social and offer a proposal to cure the fragility of the city based not on charity but on the claim of a political dimension of collective action. Starting from the analysis of initiatives such as "Un sorriso per Ballarò" and "Abbiamo un (bi)sogno" the contribution analyzes the role the incidence and the fragility of these experiences in providing answers - often filling gaps - to a general interest and how these processes of value creation can hopefully contribute to the construction of local government policies capable of addressing emerging issues.
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L’exemplum del Dinomenide Gelone tra memoria civica e storiografica

2015

La storia della Sicilia greca è scandita, nei suoi momenti chiave, dalla persistente presenza dell’immagine del Dinomenide Gelone. Questo lavoro analizza le valenze paradigmatiche assunte dalla sua figura nella memoria civica siracusana e nella produzione storiografica; inoltre ricostruisce le dinamiche politiche che hanno spinto i principali tiranni siracusani (da Dionisio I a Ierone II) a stabilire un confronto con Gelone. Il suo exemplum è utilizzato per legittimare azioni politiche e impegno antipunico; particolare attenzione è posta alla Biblioteca storica di Diodoro Siculo e al ruolo che in essa assume la figura del Dinomenide; in relazione a questi aspetti l’opera dell’Agirinense sem…

Settore L-ANT/02 - Storia GrecaThe history of Greek Sicily is marked at its key moments by the persistent image of Dinomenid Gelon. This work analyses the paradigmatic value taken on by his figure in the civic memory of the people of Syracuse and in historiographic production. It also reconstructs the political dynamics which pushed the principal tyrants of Syracuse (from Dionysius I to Hiero II) to establish comparisons with Gelon. His exemplum was used to legitimate political actions and commitment against the Carthaginianparticular attention was also given to the Library of History of Diodorus Siculus and the role that the figure of Dinomenid assumes in itregarding these aspects the work of this author seems to have sometimes the signs of a personal interpretation of history: one that cannot always be explained in relation to the use of the two principal sources for Western history Timaeus and Philistos.
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Il Polar prima del Polar: il poliziesco italo-americano tra fine Ottocento e gli anni Trenta del Novecento

2018

Tra la fine dell’Ottocento e gli anni Trenta del Novecento, alcuni Italiani immigrati negli Stati Uniti – quali, fra gli altri, Bernardino Ciambelli, Italo Stanco, Garibaldi Marto Lapolla, Louis Forgione, nonché il sodalizio letterario costituito da Michael Fiaschetti e Prosper Buranelli – si sono cimentati nel genere del poliziesco con alcuni testi che, partendo da alcune delle caratteristiche tipiche del Mystery, quali la serializzazione e l’incardinamento della fabula in uno specifico contesto urbano, insieme ad alcuni degli elementi caratteriali dei personaggi dell’Hard boiled non perdono mai di vista la peculiare ‘missione’ di denuncia politica, economica e sociale. Facendo del problem…

Settore L-FIL-LET/14 - Critica Letteraria E Letterature ComparateBetween late XIX and the first 30 years of the XX Century some Italians immigrated to the United States – such as Bernardino Ciambelli Italo Stanco Garibaldi Marto Lapolla Louis Forgione Michael Fiaschetti and Prosper Buranelli – wrote some texts that starting from the typical features of Mystery (serialization and incardination of the fabula in a specific urban context) together with some of the characteristic elements of the Hard boiled never lose sight of the peculiar 'mission' of political economic and social denunciation. Taking the political and social problems as the primary key of their works these writers want to remove the defamatory role attributed by the public opinion fomented by the press to Italian immigrated community. Their works don’t have the main intent to stage detectives that can solve a case or unmask a culprit but rather they aim to denounce social distortions corruption and injustices suffered by an entire community and not least to indicate the picture of what on the contrary that same society could have been.
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