Search results for "time factor"

showing 10 items of 3219 documents

High-throughput sequencing of RNA silencing-associated small RNAs in olive (Olea europaea L.).

2011

14 páginas, 5 figuras, 3 tablas, S4 figuras, S2 tablas

Time FactorsScienceMolecular Sequence DataSequence DatabasesPlant ScienceBiologyDeep sequencingTranscriptomesRNA interferenceGene Expression Regulation PlantGenome Analysis ToolsOleaGene expressionmicroRNAGenome DatabasesPlant GenomicsGene silencingGene Regulatory NetworksGenome SequencingBiologyConserved SequenceGeneticsPlant Growth and DevelopmentMultidisciplinaryPolymorphism GeneticBase SequenceReverse Transcriptase Polymerase Chain ReactionSequence Analysis RNAGene Expression ProfilingQRRNAGene Expression Regulation DevelopmentalHigh-Throughput Nucleotide SequencingReproducibility of ResultsGenomicsOlive treesFunctional GenomicsRNA silencingMicroRNAsRNA PlantSmall MoleculesMedicineRNA InterferenceResearch ArticleBiotechnologyDevelopmental BiologyPloS one
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Phylogenetic analysis of the isopenicillin-N-synthetase horizontal gene transfer.

1996

A phylogenetic study of the isopenicillin-N-synthetase (IPNS) gene sequence from prokaryotic and lower eukaryotic producers of beta-lactam antibiotics by means of a maximum-likelihood approach has been carried out. After performing an extensive search, rather than invoking a global molecular clock, the results obtained are best explained by a model with three rates of evolution. Grouped in decreasing order, these correspond to A. nidulans and then to the rest of the eukaryotes and prokaryotes, respectively. The estimated branching date between prokaryotic and fungal IPNS sequences (852 +/- 106 MY) strongly supports the hypothesis that the IPNS gene was horizontally transferred from bacteria…

Time FactorsSequence alignmentGram-Positive BacteriaAspergillus nidulansFungal ProteinsTransformation GeneticBacterial ProteinsSpecies SpecificityPhylogeneticsAspergillus nidulansBotanyGram-Negative BacteriaGeneticsMolecular clockMolecular BiologyGeneEcology Evolution Behavior and SystematicsPhylogenyGeneticsFungal proteinLikelihood FunctionsbiologyPhylogenetic treeModels GeneticRNA Ribosomal 5SRNA Fungalbiology.organism_classificationRNA BacterialHorizontal gene transferOxidoreductasesSequence AlignmentJournal of molecular evolution
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Determination of the cultivar and aging of Sicilian olive oils using HPLC-MS and linear discriminant analysis

2010

A large number of certified samples (84) of Sicilian olive oils arising from the eight cultivars most represented in Sicily (Biancolilla, Cerasuola, Moresca, Nocellara del Belice, Nocellara Etnea, Oglialora Messinese, Brandofino and Tonda Iblea) have been collected and analyzed by HPLC/MS using an atmospheric pressure chemical ionization (APCI) source. The sample preparation is very simple; in fact, the oil samples are diluted without any chemical derivatization. A following statistical data treatment by general discriminant analysis (GDA) allows the determination of the olive oil cultivar. Furthermore, changes in the composition of glyceridic components of the olive oils lead to easy discr…

Time FactorsSettore CHIM/10 - Chimica Degli AlimentiLDAAtmospheric-pressure chemical ionizationMass SpectrometryGlyceridesChemometricschemistry.chemical_compoundLiquid chromatography–mass spectrometryPlant OilsSettore CHIM/01 - Chimica AnaliticaSample preparationCultivarDerivatizationOlive OilSicilyChromatography High Pressure LiquidSpectroscopyChemical ionizationChromatographyagingDiscriminant AnalysisHPLC/MSVegetable oilchemistryolive oil; HPLC/MS; LDA; cultivar; agingFood AnalysiscultivarJournal of Mass Spectrometry
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Thermophilic Anaerobic Digestion of Industrial Orange Waste

2006

Thermophilic anaerobic digestion of industrial orange waste (pulp and peel) with subsequent aerobic post-treatment of the digestate was evaluated. Methane production potential was first determined in batch assays and the effects of operational parameters such as hydraulic retention times (HRT) and organic loading rates (OLR) on process performance were studied through semi-continuous digestion. In batch assays, methane production potential of about 0.49 m(3) kg(-1) volatile solids (VS)(added waste) was achieved. In semi-continuous digestion, loading at 2.8 kgVS m(-3) d(-1) (2.9 kg total solids (TS) m(-3) d(-1)) and HRT of 26 d produced specific methane yields of 0.6 m(3) kg(-1) VS (added wa…

Time FactorsSewageWaste managementChemistryMethanogenesisChemical oxygen demandTemperatureIndustrial WasteGeneral MedicineHydrogen-Ion ConcentrationWaste Disposal FluidIndustrial wasteAnaerobic digestionWaste treatmentBiodegradation EnvironmentalBioreactorsAnimal scienceDigestateBioreactorEnvironmental ChemistryAnaerobiosisMethaneWaste Management and DisposalWater Science and TechnologyWaste disposalEnvironmental Technology
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When the smile is a cue to familiarity

2000

International audience; The question discussed in the two following experiments concerns the effect of facial expressions on face recognition. Famous and unknown faces with neutral or smiling expression were presented for different inspection durations (15 ms vs 1000 ms). Subjects had to categorize these faces as famous or unknown (Experiment 1), or estimate their degree of familiarity on a rating scale (Experiment 2). Results showed that the smile increased ratings of familiarity for unfamiliar faces (Experiments 1 and 2) and for famous faces (Experiment 2). These data are discussed in the framework of current face-recognition models and are interpreted in terms of social value of the smil…

Time FactorsSocial ValuesFacial recognition systemSmiling050105 experimental psychology03 medical and health sciences0302 clinical medicineArts and Humanities (miscellaneous)Rating scaleFace perceptionMemoryHumans0501 psychology and cognitive sciencesGeneral PsychologyComputingMilieux_MISCELLANEOUSFacial expression[SCCO.NEUR]Cognitive science/Neuroscience05 social sciencesModels Theoretical[SCCO.LING]Cognitive science/LinguisticsDegree (music)Expression (mathematics)CategorizationFace (geometry)Face[SCCO.PSYC]Cognitive science/PsychologyCuesPsychologySocial psychology030217 neurology & neurosurgeryCognitive psychology
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The meaning of slow nursing in dementia care.

2015

Research literature in the dementia field lacks examples of ‘best-practices’ demonstrating concretely how it is possible to support the sense of coherence in people with dementia. The purpose of this study was to elucidate the nurses’ views concerning a caring approach that may support the sense of coherence in people with dementia. The data were collected through participant observation and focus group interviews during a four-month period in 2011. Sixteen registered nurses recruited from two Norwegian nursing homes participated in this study. The data were interpreted using a phenomenological-hermeneutical method. Three themes were identified: ‘being in the moment’, ‘doing one thing at a…

Time FactorsSociology and Political ScienceMetaphormedia_common.quotation_subjectNorwegianParticipant observation03 medical and health sciences0302 clinical medicineNursingMedicineDementiaHumans030212 general & internal medicineMeaning (existential)Qualitative Researchmedia_common030504 nursingbusiness.industryNorwayInterpretation (philosophy)ContentmentGeneral Social SciencesGeneral MedicineFocus GroupsMiddle Agedmedicine.diseaseFocus grouplanguage.human_languageNursing HomeslanguageDementiaNursing StaffEmpathy0305 other medical sciencebusinessNurse-Patient RelationsDementia (London, England)
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Protein dynamics observed by tunable mid-IR quantum cascade lasers across the time range from 10 ns to 1 s

2017

We have developed a spectrometer based on tunable quantum cascade lasers (QCLs) for recording time-resolved absorption spectra of proteins in the mid-infrared range. We illustrate its performance by recording time-resolved difference spectra of bacteriorhodopsin in the carboxylic range (1800–1700 cm− 1) and on the CO rebinding reaction of myoglobin (1960–1840 cm− 1), at a spectral resolution of 1 cm− 1. The spectrometric setup covers the time range from 4 ns to nearly a second with a response time of 10–15 ns. Absorption changes as low as 1 × 10− 4 are detected in single-shot experiments at t > 1 μs, and of 5 × 10− 6 in kinetics obtained after averaging 100 shots. While previous time-res…

Time FactorsSpectrophotometry InfraredAbsorption spectroscopyAnalytical chemistry010402 general chemistry53001 natural sciencesMolecular physicsSpectral lineAnalytical Chemistrylaw.inventionchannelrhodopsinflash photolysislawSpectral resolutionAbsorption (electromagnetic radiation)InstrumentationSpectroscopyCarbon MonoxidebiologySpectrometerChemistrybacteriorhodopsinLasers010401 analytical chemistry500 Naturwissenschaften und Mathematik::530 Physik::530 PhysikWaterBacteriorhodopsinLasertime-resolved IR spectroscopyAtomic and Molecular Physics and Optics0104 chemical sciencesSolutionsKineticsCascadeBacteriorhodopsinsmyoglobinbiology.proteinQuantum Theory
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Long-term stability study of clofarabine injection concentrate and diluted clofarabine infusion solutions

2011

Purpose: The aim of this study was to investigate the physicochemical stability of clofarabine (CAFdA) injection concentrate and ready-to-use CAFdA infusion solutions over a prolonged period of 28 days. Methods: To determine the stability of CAFdA infusion solutions, the injection concentrate (Evoltra®, 1 mg/mL, Genzyme) was diluted either with 0.9% sodium chloride or 5% glucose infusion solution. The resulting concentrations of 0.2 mg/mL or 0.6 mg/mL, respectively, were chosen to represent the lower and upper limit of the ordinary concentration range. Test solutions were stored under refrigeration (2–8°C) or at room temperature either light protected or exposed to light. CAFdA concentrati…

Time FactorsStability studyDrug StorageSodiumchemistry.chemical_elementAntineoplastic AgentsInjection concentratechemistry.chemical_compoundGlucose infusionDrug StabilitymedicineClofarabinePharmacology (medical)Clofarabine InjectionInfusions IntravenousChromatography High Pressure LiquidChromatographyAdenine Nucleotidesbusiness.industryReproducibility of ResultsPolyethylenePharmaceutical SolutionsPolyvinyl chlorideOncologychemistryArabinonucleosidesbusinessClofarabinemedicine.drugJournal of Oncology Pharmacy Practice
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Effect of polybrominated biphenyls on bromobenzene lethality in mice.

1977

Polybrominated biphenyls (PBBs) are inducers of hepatic microsomal cytochrome P450 and P1 450 in rats and mice. The purpose of this study was to determine, in mice, the effect of PBBs on the lethality of the hepatotoxin bromobenzene. Female NMRI mice were administered a single ip injection of 150 mg/kg PBBs and other mice received phenobarbital (PB), 100 mg/kg daily for 3 days, or 3‐methylcholanthrene (MC), 20 mg/kg daily for 3 days. At 24 hr after PB or MC and 24, 48, and 96 hr after PBBs animals received 3,150 mg/kg bromobenzene ip (LD85) and the time to death was recorded. Both PB and MC enhanced bromobenzene lethality and decreased the median time to death (LT50) from 23 hr in controls …

Time FactorsStereochemistryPolybrominated BiphenylsPharmacologyToxicologyLethal Dose 50chemistry.chemical_compoundMicemedicineAnimalsDrug InteractionsbiologyBiphenyl CompoundsHepatotoxinCytochrome P450PollutionGlutathionechemistryLiverBromobenzeneNmri micePhenobarbitalMicrosomebiology.proteinLethalityPhenobarbitalPolybrominated BiphenylsFemalemedicine.drugBromobenzenesMethylcholanthreneJournal of toxicology and environmental health
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The Effect of Long-Term Storage on the Biological and Histological Properties of Cryopreserved Amniotic Membrane

2011

Cryopreserved amniotic membrane (AM) is widely used in ophthalmology because of its anti-angiogenic, anti-inflammatory, and wound healing promoting capabilities. A common method to conserve the tissue is the storage in cryo-medium containing 50% glycerol at -80°C. The aim of this study was to examine the influence of storage time on the sterility as well as the histological and biological properties of cryopreserved AM.Amniotic membrane from different donors was stored in cell culture media containing 50% glycerol for different time periods, on average 4 months (group 1), 15 months (group 2), and 24 months (group 3), at -80°C. Samples of the tissue and cryo-medium were examined for bacteria…

Time FactorsSterilityBlotting WesternOrgan Preservation SolutionsMedizinTissue BanksBiologyCryopreservationAndrologyCellular and Molecular Neurosciencechemistry.chemical_compoundGlycerolHumansAmnionPolyacrylamide gel electrophoresisCryopreservationExtracellular Matrix ProteinsBacteriaBiological DressingsFungiOrgan PreservationSensory SystemsCulture MediaBlotOphthalmologyMembranechemistryTissue bankImmunologyCytokinesElectrophoresis Polyacrylamide GelWound healingBiomarkersCurrent Eye Research
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