Search results for "traction"

showing 10 items of 3716 documents

Urinary Bladder Weight and Function in a Rat Model of Mild Hyperglycemia and Its Treatment With Dapagliflozin

2019

Hypertrophy and dysfunction of the urinary bladder are consistently observed in animal models of type 1 and less consistently in those of type 2 diabetes. We have tested the effects of mild hyperglycemia (n = 10 per group) in a randomized, blinded study and, in a blinded pilot study, of type 2 diabetes (n = 6 per group) and its treatment with dapagliflozin (1 mg/kg per day) on weight, contraction, and relaxation of the rat bladder. Based on a combination of high-fat diet and a low dose of streptozotocin, animals in the main study reached a mean peak blood glucose level of about 300 mg/dl, which declined to 205 mg/dl at study end. This was associated with a small, if any, increase in bladder…

0301 basic medicinemedicine.medical_specialtyType 2 diabetesMuscle hypertrophyContractility03 medical and health scienceschemistry.chemical_compound0302 clinical medicinerelaxationDiabetes mellitusInternal medicineMedicinePharmacology (medical)DapagliflozinFenoterolOriginal ResearchPharmacologyUrinary bladderdiabetesbusiness.industrylcsh:RM1-950contractionmedicine.diseaseStreptozotocin030104 developmental biologymedicine.anatomical_structureEndocrinologylcsh:Therapeutics. Pharmacologychemistry030220 oncology & carcinogenesishyperglycemiabusinesshypertrophyurinary bladdermedicine.drugFrontiers in Pharmacology
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Drosophila Food-Associated Pheromones: Effect of Experience, Genotype and Antibiotics on Larval Behavior

2016

International audience; Animals ubiquitously use chemical signals to communicate many aspects of their social life. These chemical signals often consist of environmental cues mixed with species-specific signals-pheromones-emitted by conspecifics. During their life, insects can use pheromones to aggregate, disperse, choose a mate, or find the most suitable food source on which to lay eggs. Before pupariation, larvae of several Drosophila species migrate to food sources depending on their composition and the presence of pheromones. Some pheromones derive from microbiota gut activity and these food-associated cues can enhance larval attraction or repulsion. To explore the mechanisms underlying…

0301 basic medicinemelanogasterlcsh:Medicine[ SDV.BA ] Life Sciences [q-bio]/Animal biologyBiochemistryPheromonesLarvaeAntibioticsMedicine and Health Sciencesinsectslcsh:ScienceAnimal Signaling and CommunicationLarvaMultidisciplinaryInsect MetamorphosisbiologyAnimal BehaviorBehavior AnimalEcologyAntimicrobialscommunicationDrosophila Melanogaster[SDV.BA]Life Sciences [q-bio]/Animal biologyaggressionsex-pheromonesDrugsAnimal ModelsAttractionPupaSex pheromoneLarvacourtshipNeurosciences (Sciences cognitives)DrosophilaDrosophila melanogasterCuesrecognitionPupariationResearch ArticleattractionComputer and Information SciencesArthropodaGenotypeZoologyResearch and Analysis MethodsMicrobiology03 medical and health sciencesModel OrganismsInvertebrate ZoologySEX-PHEROMONES;MELANOGASTER;AGGRESSION;COURTSHIP;COMMUNICATION;RECOGNITION;ATTRACTION;EVOLUTION;MUTATION;INSECTSMicrobial ControlevolutionAnimalsDrosophilaSensory cuePharmacologyBehaviorMetamorphosisData Visualizationlcsh:RfungiOrganismsBiology and Life SciencesPupaebiology.organism_classificationZoologie des invertébrésInvertebratesColor Codes030104 developmental biologyFoodOdorantslcsh:QmutationZoologyEntomologyNeuroscienceDevelopmental Biology
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Redox modulation of muscle mass and function

2020

Muscle mass and strength are very important for exercise performance. Training-induced musculoskeletal injuries usually require periods of complete immobilization to prevent any muscle contraction of the affected muscle groups. Disuse muscle wasting will likely affect every sport practitioner in his or her lifetime. Even short periods of disuse results in significant declines in muscle size, fiber cross sectional area, and strength. To understand the molecular signaling pathways involved in disuse muscle atrophy is of the utmost importance to develop more effective countermeasures in sport science research. We have divided our review in four different sections. In the first one we discuss t…

0301 basic medicinemuscle[SDV]Life Sciences [q-bio]Clinical BiochemistryPhysiologyFisiologiaBiochemistryArticleAntioxidants03 medical and health sciences0302 clinical medicineAtrophymedicineAnimalsHumansMuscle Skeletallcsh:QH301-705.5Wastinglcsh:R5-920Mechanism (biology)business.industryOrganic Chemistrymedicine.diseaseMuscle atrophy3. Good healthProtein catabolismMuscular Atrophy030104 developmental biologylcsh:Biology (General)Fisiologia humanamedicine.symptomSignal transductionlcsh:Medicine (General)businessReactive Oxygen SpeciesOxidation-Reduction030217 neurology & neurosurgeryFunction (biology)Muscle contraction
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Microwear and isotopic analyses on cave bear remains from Toll Cave reveal both short-term and long-term dietary habits

2019

Dietary habits of the extinct Ursus spelaeus have always been a controversial topic in paleontological studies. In this work, we investigate carbon and nitrogen values in the bone collagen and dental microwear of U. spelaeus specimens recovered in Level 4 from Toll Cave (Moia, Catalonia, NE Iberian Peninsula). These remains have been dated to > 49,000 C-14 BP. The ability of both proxies to provide data on the diet of U. spelaeus at different times in the life-history (isotopes: average diet of life; microwear: last days/weeks before death), allows us to generate high-resolution and complementary data. Our results show lower values (delta C-13 & delta N-15) in cave bears than in strict herb…

0301 basic medicinereconstructionPleistocenecollagen extractionZoologylcsh:MedicinebonePrehistòriaArticleIsotopic Analysis Microwear Spain site Radiocarbon dating03 medical and health sciences0302 clinical medicineursus-spelaeusbiogeochemistry c-13CaveAnimalslcsh:SciencePhylogenypleistocene bearsgeographyHerbivoreMultidisciplinarygeography.geographical_feature_categoryδ13CbiologyFossilscarbonlcsh:RPaleontologyδ15Nsocial sciencesstable-isotopesbiology.organism_classificationhumanitiesDietCaves030104 developmental biologydental microwearCave bearPaleoecologylcsh:QOmnivoreCollagenToothratios030217 neurology & neurosurgeryUrsidae
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Modulation of muscle-tendon interaction in the human triceps surae during an energy dissipation task.

2017

The compliance of elastic elements allows muscles to dissipate energy safely during eccentric contractions. This buffering function is well documented in animal models but our understanding of its mechanism in humans is confined to non-specific tasks, requiring a subsequent acceleration of the body. The present study aimed to examine the behaviour of the human triceps surae muscle-tendon unit (MTU) during a pure energy dissipation task, under two loading conditions. Thirty-nine subjects performed a single-leg landing task, with- and without added mass. Ultrasound measurements were combined with 3D kinematics and kinetics to determine instantaneous length changes of MTUs, muscle fascicles, A…

030110 physiology0301 basic medicineAdultMaleMaterials sciencePhysiologyQP301.H75_Physiology._Sport.muscle-tendonStrain (injury)KinematicsAquatic ScienceConcentricMotor ActivityAchilles TendonRC120003 medical and health sciencesYoung Adult0302 clinical medicinemedicineHumansta315Muscle SkeletalMolecular BiologyEcology Evolution Behavior and SystematicsSoleus muscleAchilles tendonAnatomyFasciclemedicine.diseaseTendonBiomechanical PhenomenamodulationKineticsmedicine.anatomical_structureInsect ScienceAnimal Science and Zoologymedicine.symptom030217 neurology & neurosurgeryMuscle contractionMuscle ContractionThe Journal of experimental biology
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Identification of tasty compounds of cooked cured ham : physico-chemical and sensory approaches

1997

Abstract Tasty compounds from meat have not been studied in depth. The aim of this work was to isolate, identify and quantify tasty compounds from cooked cured ham and to link them to the sensory evaluations of the fractions from which they are extracted. The extraction of the water-soluble fraction from ham was done by an hydraulic press. The crude extract was ultrafiltered and both gel filtration and nanofiltration allowed to obtain edible fractions. Some links between the physicochemical and sensory data have been found, in particular, the umami taste was related to the presence of IMP and monosodium glutamate. The direct influence of proteolytic peptides on this taste is discussed. More…

0303 health sciencesTasteChromatography030309 nutrition & dieteticsChemistry[SDV]Life Sciences [q-bio]Extraction (chemistry)Sensory system04 agricultural and veterinary sciencesUmami040401 food science[SDV] Life Sciences [q-bio]03 medical and health sciences0404 agricultural biotechnologyNanofiltrationFood scienceComputingMilieux_MISCELLANEOUS
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« Nez et langues électroniques » : bilan et perspectives pour les huiles alimentaires

2003

Le « Nez electronique », et plus recemment la « Langue electronique » ont ete fort mediatises durant la derniere decennie. Aussi est-il necessaire, avec le recul, de faire le point sur les benefices que ces technologies peuvent apporter dans le domaine des produits alimentaires, et en particulier pour huiles vegetales. On trouve une litterature relativement abondante dans ce domaine, mais les applications qui ont reussi a franchir le cap de l’utilisation industrielle sont extremement restreintes. S’agit-il d’une frilosite des industriels pour des investissements de controle-qualite ou d’un manque de fiabilite des resultats de laboratoire ? Pourtant, la demande en outils rapides de controle-…

0303 health scienceshuile d’olive vierge030309 nutrition & dietetics010401 analytical chemistrynez électroniqueextraction des composés volatilslcsh:TP670-699[SDV.IDA] Life Sciences [q-bio]/Food engineering01 natural sciencesBiochemistryespace de tête0104 chemical sciences03 medical and health sciences[SDV.IDA]Life Sciences [q-bio]/Food engineeringCONTROLE QUALITEhuiles raffinéeslcsh:Oils fats and waxesComputingMilieux_MISCELLANEOUSFood ScienceOléagineux, Corps gras, Lipides
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Hormone replacement therapy improves contractile function and myonuclear organization of single muscle fibres from postmenopausal monozygotic female …

2013

Ageing is associated with a decline in muscle mass and strength leading to increased physical dependency in old age. Postmenopausal women experience a greater decline than men of similar age in parallel with the decrease in female sex steroid hormone production. We recruited six monozygous female twin pairs (55-59 years old) where only one twin pair was on hormone replacement therapy (HRT use = 7.8 ± 4.3 years) to investigate the association of HRT with the cytoplasmic volume supported by individual myonuclei (myonuclear domain (MND) size,) together with specific force at the single fibre level. HRT use was associated with a significantly smaller (∼27%; P < 0.05) mean MND size in muscle fib…

0303 health sciencesmedicine.medical_specialtySpecific forcePhysiologybusiness.industrymedicine.medical_treatmentMuscle mass03 medical and health sciencesSteroid hormone0302 clinical medicineEndocrinologySingle muscleAgeingTransgender hormone therapyInternal medicineMyosinmedicinemedicine.symptom10. No inequalitybusiness030217 neurology & neurosurgery030304 developmental biologyMuscle contractionThe Journal of Physiology
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Innovative Green Technologies of Intensification for Valorization of Seafood and Their By-Products

2019

The activities linked to the fishing sector generate substantial quantities of by-products, which are often discarded or used as low-value ingredients in animal feed. However, these marine by-products are a prominent potential good source of bioactive compounds, with important functional properties that can be isolated or up-concentrated, giving them an added value in higher end markets, as for instance nutraceuticals and cosmetics. This valorization of fish by-products has been boosted by the increasing awareness of consumers regarding the relationship between diet and health, demanding new fish products with enhanced nutritional and functional properties. To obtain fish by-product-derived…

030309 nutrition & dieteticsEmerging technologiesmedia_common.quotation_subjectPharmaceutical ScienceCosmeticsReviewCosmetics03 medical and health sciencesIngredient0404 agricultural biotechnologyNutraceuticalinnovative green technologieshigh-added value compoundsDrug DiscoveryFish ProductsAdded valueAnimalsHumansQuality (business)Ultrasonics14. Life underwaterPharmacology Toxicology and Pharmaceutics (miscellaneous)functional foodsmedia_common0303 health sciencesBiological Productsseafood by-productsSupercritical fluid extractionChromatography Supercritical FluidGreen Chemistry Technology04 agricultural and veterinary sciencesFish products040401 food scienceSeafoodDietary SupplementsBiochemical engineeringBusiness
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Characterisation of odour active compounds along extraction process from pea flour to pea protein extract

2013

International audience; Pisum sativum, rich in proteins, represents a main interest for human food. Nevertheless, pea products are underused because of their organoleptic characteristics. The extraction process of the proteins can partly explain the development of the typical flavour.The objective of the present study was to identify odour active compounds and to follow their evolution during four steps of the process (from pea flour to pea protein).Firstly, volatile compounds were extracted by Solvent Assisted Flavour Evaporation from each step and analysed by Gas Chromatography coupled with Mass Spectrometry and Olfactometry. Secondly, the volatile compounds, identified as odour active in…

030309 nutrition & dieteticsFlavourOrganolepticPisum03 medical and health sciences0404 agricultural biotechnologyProtein purification[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyProtein extractionOdour-active compoundsLegumePisum sativum2. Zero hunger0303 health sciencesChromatographybiologyPea proteinExtraction (chemistry)fungifood and beverages04 agricultural and veterinary sciencesbiology.organism_classification040401 food scienceSAFEGC–OGas chromatography[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood Science
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