Search results for "traction"

showing 10 items of 3716 documents

Vertebrobasilar junction giant aneurysm: Lessons learned from a neurosurgical audit and anatomical investigation.

2015

The treatment of vascular lesions of the vertebrobasilar junction (VBJ) remains a challenging task in the neurosurgical practice and the gold standard therapy is still under debate. In this article, the authors report a detailed postmortem study of a VBJ giant aneurysm (GA) previously endovascularly treated. Although the decision-making process for the vast majority of neurosurgical treatment can nowadays be accurately carried out during the preoperative planning (i.e., with the aid of neuroimaging fusion protocols, neuronavigation platforms, etc.) meant to maximize the anatomical understanding of the lesions and minimize possible intraprocedural challenges, this postmortem study represents…

medicine.medical_specialtyNeuronavigationskull base approachesAuditvertebrobasilar junction aneurysmsNeurosurgical ProceduresAneurysmClinical historymedicineHumansMedical physicsVertebral ArterySkull BaseMedical AuditPreoperative planningSettore MED/27 - Neurochirurgiabusiness.industryEndovascular ProceduresAngiography Digital SubtractionIntracranial AneurysmGeneral MedicineBalloon OcclusionMiddle Agedmedicine.diseaseSurgeryanatomical dissectionBasilar ArterySurgeryFemaleneurosurgical auditNeurology (clinical)AutopsybusinessBritish journal of neurosurgery
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Presence of muscarinic inhibitory and absence of nicotinic excitatory receptors at the terminal sympathetic nerves of chicken hearts.

1976

Nicotine (2 X 10(-4) M) or acetylcholine (5.5 X 10(-4) M) in the presence of 3 X 10(-6) M atropine did not increase the rate or amplitude of contraction in isolated atria or ventricular strips of the chicken heart; both drugs also did not cause an output of noradrenaline or adrenaline and did not evoke antidromic discharges in the right sympathetic nerves of isolated perfused chicken hearts. In contrast, "high K+-solutions" evoked an output of noradrenaline and adrenaline and caused a burst of antidromic discharges. Dimethylphenylpiperazine (DMPP; 3.1 X 10(-4) M), by a tyramine-like action, elicited a small output of noradrenaline and increased rate and amplitude of contraction" but did not…

medicine.medical_specialtyNicotineSympathetic Nervous SystemEpinephrineTyramineStimulationIn Vitro TechniquesReceptors NicotinicInhibitory postsynaptic potentialNorepinephrineHeart RateInternal medicineMuscarinic acetylcholine receptormedicineAnimalsReceptors CholinergicEvoked PotentialsPharmacologyChemistryMyocardiumHeartGeneral MedicineMyocardial ContractionReceptors MuscarinicAcetylcholineAntidromicAtropineNicotinic agonistEndocrinologyExcitatory postsynaptic potentialCatsPotassiumDimethylphenylpiperazinium IodideChickensAcetylcholinemedicine.drugNaunyn-Schmiedeberg's archives of pharmacology
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Inhibition of calcium entry induced by cularines and isocrasifoline in uterine smooth muscle.

1991

Abstract The effects of nifedipine, papaverine and four benzylisoquinoline alkaloids (cularine, cularidine, celtisine and isocrasifoline) were studied in isolated rat uterus in order to clarify the mechanism of their relaxant action. All the compounds tested completely relaxed KCl-induced contractions and totally or partially inhibited oxytocin-induced rhythmic contractions. Only papaverine acted intracellularly, promoting relaxation of contractile responses induced by oxytocin or vanadate in a Ca 2+ -free medium. In spite of the structural relationship between papaverine and the other alkaloids, the mechanism of their relaxant action is not the same. The activities of cularine derivatives …

medicine.medical_specialtyNifedipineIn Vitro TechniquesOxytocinchemistry.chemical_compoundUterine ContractionAlkaloidsNifedipineCoumarinsInternal medicinePapaverinemedicineAnimalsVanadateBenzylisoquinolinePharmacologyPapaverineChemistryAlkaloidMuscle SmoothRats Inbred StrainsIsoquinolinesRatsEndocrinologyOxytocinMechanism of actionCalciumFemalemedicine.symptomVanadatesmedicine.drugMuscle contractionMuscle ContractionEuropean journal of pharmacology
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Inhibitory effects of okadaic acid on rat uterine contractile responses to different spasmogens

1997

In the present study, we examined the effects of okadaic acid, a selective inhibitor of type I and 2A protein phosphatases, on the mechanical responses evoked by oxytocin, K + - and Na + -modified solutions and ouabain in estrogen-primed rat myometrium. Oxytocin elicited a rapid, phasic contraction followed by rhythmic oscillations. The phasic response was partially resistant to the absence of external Ca 2+ . Okadaic acid (1 μM) and the L-type calcium channel blocker nifedipine (1 μM) abolished the oscillatory component and reduced the initial, phasic response to about 80% of the control response. High K + (60 mM) solution, ouabain (1 mM), K + -free medium and low Na + (25 mM) solution ind…

medicine.medical_specialtyNifedipinePhosphatasechemistry.chemical_elementCalciumOxytocinOuabainUterine Contractionchemistry.chemical_compoundNifedipineInternal medicineOkadaic AcidmedicineExtracellularAnimalsPharmacology (medical)Rats WistarOuabainPharmacologyDose-Response Relationship DrugSodiumMyometriumOkadaic acidCalcium Channel BlockersPhosphoric Monoester HydrolasesRatsAmilorideEndocrinologychemistryPotassiumCalciumFemalemedicine.drugFundamental & Clinical Pharmacology
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Knowledge Discovery from Microbiology Data: Many-Sided Analysis of Antibiotic Resistance in Nosocomial Infections

2005

Nosocomial infections and antimicrobial resistance (AR) are highly important problems that impact the morbidity and mortality of hospitalized patients as well as their cost of care. The goal of this paper is to demonstrate our analysis of AR by applying a number of various data mining (DM) techniques to real hospital data. The data for the analysis includes instances of sensitivity of nosocomial infections to antibiotics collected in a hospital over three years 2002-2004. The results of our study show that DM makes it easy for experts to inspect patterns that might otherwise be missed by usual (manual) infection control. However, the clinical relevance and utility of these findings await th…

medicine.medical_specialtyOperations researchmedicine.drug_classHospitalized patientsComputer scienceKnowledge engineeringAntibioticsAntibiotic resistanceKnowledge extractionmedicineInfection controlRelevance (information retrieval)Intensive care medicineCost of careProspective cohort study
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Conflict of interest reporting in dentistry meta-analyses: A systematic review

2013

Objectives: The issue of reporting conflicts of interest (COI) in medical research has come under scrutiny over the past decade. Absolute transparency is important when dealing with conflicts of interest to provide readers with all essential information required to make an informative decision of the results. The key objective of this study was to examine the prevalence of reporting conflicts of interest in therapeutic dental meta-analyses of Randomized Control Trials (RCTs), and to investigate possible associations with other categorical variables. Study Design: We conducted an extensive literature search across multiple databases to search for relevant review articles for this study. We u…

medicine.medical_specialtyOral Medicine and PathologyScrutinybusiness.industryAlternative medicineConflict of interestMEDLINEDentistryOdontologíaReview:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludTransparency (behavior)law.inventionRandomized controlled trialData extractionlawUNESCO::CIENCIAS MÉDICASmedicinebusinessGeneral DentistryCategorical variableJournal of Clinical and Experimental Dentistry
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Callus distraction of the femur and tibia. Experience with the Monofixator - indications for reosteosynthesis

1998

In a 4-year period, 18 patients underwent callus distraction of the femur or tibia with the use of a unilateral external fixator. Twelve patients had post-traumatic bone loss resulting from complex lower-limb fractures. The bony defect was located in the tibia in 11 cases and in the femur in one case. All patients had major associated soft-tissue lesions. The length of the bony defect averaged 6.25 cm. Eight fractures were infected at the beginning of treatment. Six other patients underwent callus distraction for reasons of limb shortening. Five femora and one tibia were lengthened. The average increase in length was 6.5 cm. There were no fixator-related complications during distraction. Th…

medicine.medical_specialtyOsteosynthesisbusiness.industrymedicine.medical_treatmentSurgerylaw.inventionIntramedullary rodExternal fixationlawDistractionOrthopedic surgeryEmergency MedicinemedicineDistraction osteogenesisOrthopedics and Sports MedicineSurgeryFemurTibiabusinessDer Unfallchirurg
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Management of aneurysmal subarachnoid hemorrhage: State of the art and future perspectives

2017

Background: Aneurysmal subarachnoid hemorrhage (SAH) accounts for 5% of strokes and carries a poor prognosis. It affects around 6 cases per 100,000 patient years occurring at a relatively young age. Methods: Common risk factors are the same as for stroke, and only in a minority of the cases, genetic factors can be found. The overall mortality ranges from 32% to 67%, with 10–20% of patients with long-term dependence due to brain damage. An explosive headache is the most common reported symptom, although a wide spectrum of clinical disturbances can be the presenting symptoms. Brain computed tomography (CT) allow the diagnosis of SAH. The subsequent CT angiography (CTA) or digital subtraction …

medicine.medical_specialtyOutcome; subarachnoid hemorrhage; treatment; vasospasmSubarachnoid hemorrhagesubarachnoid hemorrhageIschemia030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineCerebral vasospasmAneurysmInternal medicinemedicinecardiovascular diseasesStrokevasospasmOutcometreatmentmedicine.diagnostic_testbusiness.industryVasospasmDigital subtraction angiographymedicine.diseaseAnesthesiaAngiographyNeurovascular: Review ArticleCardiologySurgeryNeurology (clinical)business030217 neurology & neurosurgerySurgical Neurology International
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Jugular pacing lead extraction with laser sheath: a case report.

2010

Over the past 20 years, the number of patients with pacemakers (PM) or implantable cardioverter defibrillators has risen markedly; consequently, an increasing number of lead-removal procedures have become necessary. A 64-year-old woman presenting with an infected device pocket and positive bacterial cultures ( Staphylococcus aureus ) was admitted to our department for lead removal; in 1991, she underwent VVI PM implantation for atrioventricular II degree Mobitz 1 block, and a unipolar lead was introduced via the left jugular vein. The procedure was performed in our Electrophysiology Lab with a cardiac surgeon on standby, using an excimer laser system emitting the energy at the tip of a flex…

medicine.medical_specialtyPacemaker ArtificialProsthesis-Related Infectionslaw.inventionlawPhysiology (medical)Jugular veinlead extracion laser sheatMedicineHumansLead (electronics)Device RemovalEndocarditisbusiness.industryLasersCardiac Pacing ArtificialMiddle AgedStaphylococcal InfectionsLaserSettore MED/11 - Malattie Dell'Apparato CardiovascolareSurgeryCardiothoracic surgeryFluoroscopyFemaleJugular VeinsCardiology and Cardiovascular MedicinebusinessLead extractionEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
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THE ROLE OF ENDOSCOPY IN ACUTE RECURRENT AND CHRONIC PANCREATITIS AND PANCREATIC CANCER

1999

Endoscopy plays an important role in the diagnosis and treatment of acute and chronic pancreatitis as well as pancreatic cancer. Sphincterotomy and stone removal in biliary pancreatitis, stone extraction and drainage in chronic pancreatitis, and stent implantation in pancreatic cancer are the predominant procedures. With endoscopy, minimal invasive techniques are at hand to solve urgent and long term problems.

medicine.medical_specialtyPancreatic diseaseCost-Benefit AnalysisGastroenterologyDiagnosis DifferentialPancreatic cancerInternal medicineSecondary PreventionmedicineHumansStone extractionEndoscopy Digestive Systemmedicine.diagnostic_testbusiness.industryGastroenterologymedicine.diseaseEndoscopyPancreatic NeoplasmsTreatment Outcomemedicine.anatomical_structurePancreatitisAcute DiseaseChronic DiseasePancreatitisStone removalNeoplasm Recurrence LocalDifferential diagnosisPancreasbusinessGastroenterology Clinics of North America
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