Search results for "tracts"
showing 10 items of 803 documents
Osteonecrosis of the jaw after long-term oral bisphosphonates, followed by short-term denosumab treatment for osteoporosis: a case report
2014
Bisphosphonates and denosumab are antiresoptive agents and are mainly used for management of metastatic bone cancer, osteoporosis and other diseases. Bisphosphonates (BP) can reduce skeletal related events (SRE) by 30–50%1; denosumab (D) has been found even more effective than BP2. BP and D have been both associated to osteonecrosis of the jaw (ONJ). We report a case of an osteoporotic woman (62 yrs), complaining maxillary intense pain after a recent tooth molar extraction, observed in July 2013 at our centre. She mentioned previous treatments with monthly ibandronate (Bonviva ® 150 mg) per os (from January 2003 to April 2010), risedronate (35 mg weekly, from May 2010 to May 2012) and two a…
O2.1. FIRST EPISODE PSYCHOSIS PATIENTS ACROSS EUROPE DIFFER IN INTELLECTUAL QUOTIENT (IQ) AND EXPOSURE TO ENVIRONMENTAL HAZARDS
2018
Abstract Background Children who later develop Schizophrenia on average are more likely to present with lower IQ; this has been considered evidence for the neurodevelopmental theory of schizophrenia. Though, recent studies have shown that first episode psychosis patients with a history of cannabis use have significantly higher premorbid and current IQ compared to those who never used it. This suggests that abnormal early neurodevelopment does not explain the aetiology of all cases of Schizophrenia, leaving space to environmental hazards. The present study aims to: investigate differences in IQ, as a marker of neurodevelopment, and in exposure to environmental risk factors in a large sample …
The combination of laser-assisted surgery with PRP for the treatment of BRONJ in cancer patient. A pilot study
2014
Aim. Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a well-known potential complication of bisphosphonates (BPs) therapy and its treatment could reckon on different approaches. Recently, encouraging results for BRONJ were showed from some clinical studies using Er, Cr: YSGG laser-assisted surgery. Platelet-Rich Plasma (PRP), a new approach to promote tissue regeneration and healing, may be a promising complementary therapy. The aim of this pilot study is to study the effectiveness, in terms of clinical healing, of a combined treatment (laserassisted surgery and topical PRP) for BRONJ in a group of cancer patients. Methods. Ten oncological patients (3 males, 7 females; aged 69-89…
Description of a new protocol with application of PRP in post-extraction sockets of a patient treated with aminobisphosphonate
2014
Background. Platelet-rich plasma (PRP), an autologous product rich of growth factors, is an adjunctive bio-material able to promote healing in dental surgery, especially in elderly. It is also used for treating bisphosphonate-related osteonecrosis of the jaw (BRONJ) and for application in post-extraction alveolar site in order to obtain mucosa healing and reduce BRONJ risk. Aim. To describe a dental extraction PRP enriched protocol adopted in a patient treated with aminobisphosphonate in order to evaluate the healing of the post-extraction alveolar site. Case report. An osteoporotic woman (71 yrs), treated with alendronate per os for 10 years and suspended from 1 year, currently with vitami…
Oral Abstract Sessions
2014
FREE-LIVING AND LABORATORY-BASED GAIT ASSESSMENTS PROVIDE CONGRUENT RESULTS AMONG 75-YEAR-OLD MEN AND WOMEN
2018
It is often wondered how representative laboratory-based assessments are of the free-living condition. Indeed, free-living gait is more predictive of self-reported falls history compared to laboratory-based gait. However, explicit explorations of the relationship between laboratory-based and free-living based gait parameters remain scarce. Therefore, this association was studied using a trunk-worn accelerometer during a laboratory-based 6-min walking test, and in free-living conditions (6 days) in a sample of 75-year-old men and women (N=77). Gait quantity (minutes of walking per day, distance covered for free-living and laboratory, respectively) and quality (assessed with multiscale entrop…
A chromatographic objective function to characterise chromatograms with unknown compounds or without standards available
2015
Abstract Getting useful chemical information from samples containing many compounds is still a challenge to analysts in liquid chromatography. The highest complexity corresponds to samples for which there is no prior knowledge about their chemical composition. Computer-based methodologies are currently considered as the most efficient tools to optimise the chromatographic resolution, and further finding the optimal separation conditions. However, most chromatographic objective functions (COFs) described in the literature to measure the resolution are based on mathematical models fitted with the information obtained from standards, and cannot be applied to samples with unknown compounds. In …
The cypsela (achene) of Echinacea purpurea as a diffusion unit of a community of microorganisms
2021
AbstractEchinacea purpurea is a plant cultivated worldwide for its pharmaceutical properties, mainly related to the stimulation of the immune system in the treatment of respiratory infections. The cypselas (fruits) of E. purpurea were examined in order to investigate the presence, localization and potential function(s) of endophytic microorganisms. Electron and confocal microscopy observations showed that three different components of microorganisms were associated to cypselas of E. purpurea: (i) one endocellular bacterial component in the cotyledons, enclosed within the host membrane; (ii) another more generic bacterial component adhering to the external side of the perianth; and (iii) a f…
DO FLEXIBLE AND TENACIOUS GOAL PURSUIT ALLEVIATE THE INFLUENCES OF FUNCTIONAL DECLINE TO ACTIVITY PARTICIPATION?
2018
Assimilative and accommodative coping strategies have hardly been studied in relation to activity participation when facing functional decline. We investigated whether tenacious goal pursuit (TGP) and flexible goal adjustment (FGA) influence the association between physical or cognitive performance, and physical activity or participation in other hobbies. Participants were 78-93-year-old community-dwelling people (n=187). TGP and FGA were self-evaluated with distinct scales (ranges 5–25). Physical performance was assessed with Short Physical Performance Battery (SPPB; 0–12) and cognitive performance with Mini-Mental State Examination (MMSE; 0–30). Physical activity (0–5) and participation i…
Effect of the basidiomycete Poria cocos on experimental dermatitis and other inflammatory conditions.
1997
The hydroalcoholic extract from P. cocos was examined for oral and topical anti-inflammatory activities. It proved to be active against carrageenan, arachidonic acid, tetradecanoyl phorbol acetate (TPA) acute edemas, TPA chronic inflammation and oxazolone delayed hypersensitivity in mice. Two lanostane-type triterpenes were isolated and identified by spectroscopic methods as dehydrotumulosic and pachymic acids. Their ID50 on acute TPA edema was 4.7 x 10(-3) and 6.8 x 10(-4) mumol/ear, respectively.