Search results for "traditional medicine"

showing 10 items of 422 documents

Euphosantianane E–G: Three New Premyrsinane Type Diterpenoids from Euphorbia sanctae-catharinae with Contribution to Chemotaxonomy

2019

Euphorbia species were widely used in traditional medicines for the treatment of several diseases. From the aerial parts of Egyptian endemic plant, Euphorbia sanctae-catharinae, three new premyrsinane diterpenoids, namely, euphosantianane E&ndash

Pharmaceutical ScienceAgglomerative hierarchical clustering01 natural sciencesArticlepremyrsinane diterpenoidsAnalytical Chemistrylcsh:QD241-441TerpeneType (biology)lcsh:Organic chemistryEuphorbiaDrug DiscoveryPhysical and Theoretical ChemistryEuphorbiaMolecular StructurebiologyTraditional medicinePlant Extracts010405 organic chemistryOrganic ChemistryeuphorbiaceaeEuphorbiaceaeEuphorbia sanctae-catharinaePlant Components Aerialendemic plantchemotaxonomic significancebiology.organism_classificationAntineoplastic Agents Phytogenic0104 chemical sciences010404 medicinal & biomolecular chemistryChemistry (miscellaneous)Chemotaxonomyeuphosantianane E–G<i>Euphorbia sanctae-catharinae</i>Molecular MedicineEgyptDiterpenesDrug Screening Assays AntitumorMolecules
researchProduct

Medicinal Plants in the Treatment of Depression: Evidence from Preclinical Studies.

2021

AbstractMedicinal plants and their extracts are natural remedies with enormous potential for treating various diseases, including depression and anxiety. In the case of depression, hundreds of plants have traditionally been used in folk medicine for generations. Different plant extracts and natural products have been analyzed as potential antidepressant agents with validated models to test for antidepressant-like effects in animals, although other complementary studies have also been employed. Most of these studies focus on the possible mediators implicated in these potential effects, with dopamine, serotonin, and noradrenaline being the principal neurotransmitters implicated, both through …

Pharmaceutical ScienceAnalytical Chemistrylaw.invention03 medical and health sciences0302 clinical medicinelawDrug DiscoveryMedicineAnimalsHumansMedicinal plantsDepression (differential diagnoses)PharmacologyFolk medicineKavaPlants MedicinalTraditional medicinebusiness.industryDepressionPlant ExtractsOrganic ChemistryAntidepressive AgentsComplementary and alternative medicine030220 oncology & carcinogenesisMolecular MedicineAntidepressantNarrative reviewPhytotherapybusiness030217 neurology & neurosurgeryHypericumPhytotherapyPlanta medica
researchProduct

2019

Phytochemical investigations of ethanol root bark and stem bark extracts of Cleistochlamys kirkii (Benth.) Oliv. (Annonaceae) yielded a new benzopyranyl cadinane-type sesquiterpene (cleistonol, 1) alongside 12 known compounds (2–13). The structures of the isolated compounds were established from NMR spectroscopic and mass spectrometric analyses. Structures of compounds 5 and 10 were further confirmed by single crystal X-ray crystallographic analyses, which also established their absolute stereochemical configuration. The ethanolic crude extract of C. kirkii root bark gave 72% inhibition against the chloroquine-sensitive 3D7-strain malaria parasite Plasmodium falciparum at 0.01 μg/mL. The is…

Pharmaceutical ScienceSesquiterpene01 natural sciencesAnalytical Chemistrychemistry.chemical_compoundDrug DiscoveryCytotoxic T cellPhysical and Theoretical ChemistryCytotoxicityIC50biologyTraditional medicine010405 organic chemistryOrganic ChemistryPlasmodium falciparumbiology.organism_classification0104 chemical sciences010404 medicinal & biomolecular chemistrychemistryPhytochemicalChemistry (miscellaneous)Annonaceaevisual_artvisual_art.visual_art_mediumMolecular MedicineBarkMolecules
researchProduct

Euphosantianane A–D: Antiproliferative Premyrsinane Diterpenoids from the Endemic Egyptian Plant Euphorbia Sanctae-Catharinae

2018

Euphorbia species are rich in diterpenes. A solvent extraction of Euphorbia sanctae-catharinae, a species indigenous to the Southern Sinai of Egypt, afforded several premyrsinane diterpenoids (1&ndash

Pharmaceutical ScienceTumor cells01 natural sciencesAnalytical ChemistryTDDTF-ECDlcsh:QD241-441tumor anti-proliferative activitylcsh:Organic chemistryDrug DiscoveryPhysical and Theoretical ChemistrySolvent extractionA549 cellEuphorbiabiologyTraditional medicine010405 organic chemistryChemistryOrganic ChemistryEuphorbiaceaeEuphorbiaceaediterpenesEuphorbia sanctae-catharinaebiology.organism_classification0104 chemical sciences010404 medicinal & biomolecular chemistryChemistry (miscellaneous)flavonoidsMolecular Medicine<i>Euphorbia sanctae-catharinae</i>Molecules
researchProduct

COX-2 and sPLA2 inhibitory activity of aqueous extract and polyphenols of Rhizophora mangle (red mangrove)

2006

The aqueous extract of Rhizophora mangle bark and its polyphenolic fractions showed remarkable in vitro antiinflammatory activity in a preliminary study. The low molecular weight fraction exhibited cyclooxygenase-2 inhibitory activity while the total aqueous extract and the low molecular weight fraction showed secretory phospholipase A(2) inhibitory activity.

PharmacognosyPhospholipases Alaw.inventionchemistry.chemical_compoundPhenolslawDrug DiscoveryPlant BarkHumansPhenolsEnzyme InhibitorsRhizophora mangleFlavonoidsPharmacologyCyclooxygenase 2 InhibitorsDose-Response Relationship DrugTraditional medicinebiologyPlant ExtractsChemistryMembrane ProteinsPolyphenolsRhizophoraceaeGeneral Medicinebiology.organism_classificationCyclooxygenase 2Polyphenolvisual_artPlant Barkvisual_art.visual_art_mediumRhizophoraceaeBarkPhytotherapyPhytotherapyFitoterapia
researchProduct

Phenolic compounds of herbal infusions obtained from some species of the Lamiaceae family

2018

Abstract The present investigation was to estimate the total phenolic content and composition of flavonoids and hydroxycinnamic acids in herbal infusions obtained from aerial parts of three Lamiaceae species (Dracocephalum moldavica, Ocimum americanum and Satureja hortensis). The total phenolic content of herbal infusions was determined using a spectrophotometric method, whereas the individual phenolics were assessed by high-performance liquid chromatography (HPLC). The HPLC method was developed and validated. The total phenolic content was measured by applying the Folin-Ciocalteu method with reference to gallic acid. Results were in the range from 29.39 to 65.38 mg estimated as gallic acid…

Pharmacology toxicologyPharmacyphenolic compounds01 natural sciencesBiochemistryOcimum americanumspectrophotometryMedicineDracocephalum moldavicaMolecular BiologyPharmacologyTraditional medicinebiologySatureja hortensis010405 organic chemistrybusiness.industry010401 analytical chemistryRfood and beveragesGeneral Medicinebiology.organism_classification0104 chemical sciencesMedicineLamiaceaeHPLCbusinessCurrent Issues in Pharmacy and Medical Sciences
researchProduct

WITHDRAWN: Herbalists, traditional healers and pharmacists: a view of the tuberculosis in Ghana

2015

The Publisher regrets that this article is an accidental duplication of an article that has already been published, http://dx.doi.org/. The duplicate article has therefore been withdrawn.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.

Pharmacology Toxicology and Pharmaceutics(all)medicine.medical_specialtyTuberculosisTraditional medicinebusiness.industryFamily medicineAlternative medicinemedicineGeneral Pharmacology Toxicology and Pharmaceuticsbusinessmedicine.diseaseRevista Brasileira de Farmacognosia
researchProduct

Combining the wisdoms of traditional medicine with cutting-edge science and technology at the forefront of medical sciences

2019

Abstract Background A central topic is to bring traditional medicine to a new horizon by integrating the latest advances in genomic, metabolomic, and system biological approaches, in order to re-examine the wisdom and knowledge of traditional Chinese medicine (TCM) and other traditional medicines. Purpose A new consortium has been formed at a conference of the Harvard Medical School, Boston, on October 29–30, 2018. The main goal was to build a collaborative platform for the scientific investigation of traditional medicine with cutting edge sciences and technologies at the forefront of biomedicine. Results Traditional medicines are largely experience-based, but the scientific basis is largel…

Pharmacology0303 health sciencesTraditional medicinebusiness.industryMedical schoolPharmaceutical ScienceOrgan functionTraditional Chinese medicine03 medical and health sciences0302 clinical medicineComplementary and alternative medicineDrug development030220 oncology & carcinogenesisDrug DiscoveryAcupunctureMolecular MedicineMedicinal herbsIntegrative medicinebusinessBiomedicine030304 developmental biologyPhytomedicine
researchProduct

Traditional Chinese Medicine Remedy to Jury: The Pharmacological Basis for the Use of Shikonin as an Anticancer Therapy

2013

Shikonin is the major constituent of the root of Lithospermum erythrorhizon, which has been used in traditional Chinese medicine to treat external wounds, burns, or dermatitis for centuries. Nowadays, this root is commonly used as an herbal medicine against cancer. Studies carried out over the past 30 years have demonstrated that many of the effects historically associated with the use of this root have a scientific basis, with shikonin and its derivatives being responsible for its pharmacological properties. These include both anti-inflammatory and anticancer effects. While previous summaries have focused on the pharmacokinetics and toxicity of shikonin, the aim of this review is to report…

PharmacologyAntitumor activitybiologyTraditional medicinebusiness.industryOrganic ChemistryAnti-Inflammatory AgentsAntineoplastic AgentsTraditional Chinese medicineLithospermum erythrorhizonbiology.organism_classificationPlant RootsBiochemistryNeoplasmsChinese traditionalDrug DiscoveryHumansMolecular MedicineMedicineMedicine Chinese TraditionalbusinessNaphthoquinonesCurrent Medicinal Chemistry
researchProduct

Hypotensive Effect ofPistacia lentiscusL

1987

AbstractThe present studies were undertaken to confirm the hypotensive effect of Pistacia lentiscus L. in normotensive urethane anaesthetized Wistar rats. It was shown that lyophilized aqueous extract caused a dose-dependent decreased of the systemic arterial blood pressure. Acute toxicity was also determined. Phytochemical analysis revealed the presence of steroids-triterpenes, catechin tannins, flavonoids, sugars, resins and saponins.

PharmacologyAqueous extractchemistry.chemical_compoundBlood pressurebiologychemistryPhytochemicalTraditional medicinePistacia lentiscusMolecular MedicineCatechinbiology.organism_classificationAcute toxicityInternational Journal of Crude Drug Research
researchProduct