COX-2 and sPLA2 inhibitory activity of aqueous extract and polyphenols of Rhizophora mangle (red mangrove)

6533b826fe1ef96bd12848f3

RESEARCH PRODUCT

COX-2 and sPLA2 inhibitory activity of aqueous extract and polyphenols of Rhizophora mangle (red mangrove)

María José Alcaraz Evangelina Marrero M. J. Abad Gleiby Melchor Paulina Bermejo Javier Megías Janet Sánchez Angel Villar A Escobar Elizabeth De Armas

subject

Pharmacognosy Phospholipases A law.invention chemistry.chemical_compound Phenols law Drug Discovery Plant Bark Humans Phenols Enzyme Inhibitors Rhizophora mangle Flavonoids Pharmacology Cyclooxygenase 2 Inhibitors Dose-Response Relationship Drug Traditional medicine biology Plant Extracts Chemistry Membrane Proteins Polyphenols Rhizophoraceae General Medicine biology.organism_classification Cyclooxygenase 2 Polyphenol visual_art Plant Bark visual_art.visual_art_medium Rhizophoraceae Bark Phytotherapy Phytotherapy

description

The aqueous extract of Rhizophora mangle bark and its polyphenolic fractions showed remarkable in vitro antiinflammatory activity in a preliminary study. The low molecular weight fraction exhibited cyclooxygenase-2 inhibitory activity while the total aqueous extract and the low molecular weight fraction showed secretory phospholipase A(2) inhibitory activity.

year	journal	country	edition	language
2006-06-01	Fitoterapia

https://doi.org/10.1016/j.fitote.2006.03.009

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