Search results for "Rhizophoraceae"

showing 3 items of 3 documents

Polyketide Derivatives from Mangrove Derived Endophytic Fungus Pseudopestalotiopsis theae

2020

Chemical investigation of secondary metabolites from the endophytic fungus Pseudopestalotiopsis theae led to the isolation of eighteen new polyketide derivatives, pestalotheols I&ndash

Models MolecularMagnetic Resonance SpectroscopyStereochemistryPharmaceutical Science010402 general chemistry01 natural sciencesArticlePolyketidepolyketideDrug DiscoverymedicineEndophytesCytotoxicityPharmacology Toxicology and Pharmaceutics (miscellaneous)IC50lcsh:QH301-705.5endophytic fungusbiologyMolecular Structure010405 organic chemistryChemistryAbsolute configurationFungibiology.organism_classification0104 chemical sciencesAcinetobacter baumanniiPseudopestalotiopsis theaelcsh:Biology (General)<i>Pseudopestalotiopsis theae</i>PolyketidesFermentationColistincytotoxicityRhizophoraceaeAntibacterial activityTwo-dimensional nuclear magnetic resonance spectroscopymedicine.drugMarine Drugs
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COX-2 and sPLA2 inhibitory activity of aqueous extract and polyphenols of Rhizophora mangle (red mangrove)

2006

The aqueous extract of Rhizophora mangle bark and its polyphenolic fractions showed remarkable in vitro antiinflammatory activity in a preliminary study. The low molecular weight fraction exhibited cyclooxygenase-2 inhibitory activity while the total aqueous extract and the low molecular weight fraction showed secretory phospholipase A(2) inhibitory activity.

PharmacognosyPhospholipases Alaw.inventionchemistry.chemical_compoundPhenolslawDrug DiscoveryPlant BarkHumansPhenolsEnzyme InhibitorsRhizophora mangleFlavonoidsPharmacologyCyclooxygenase 2 InhibitorsDose-Response Relationship DrugTraditional medicinebiologyPlant ExtractsChemistryMembrane ProteinsPolyphenolsRhizophoraceaeGeneral Medicinebiology.organism_classificationCyclooxygenase 2Polyphenolvisual_artPlant Barkvisual_art.visual_art_mediumRhizophoraceaeBarkPhytotherapyPhytotherapyFitoterapia
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Cytosporones, coumarins, and an alkaloid from the endophytic fungus Pestalotiopsis sp. isolated from the Chinese mangrove plant Rhizophora mucronata

2009

Chemical examination of the endophytic fungus Pestalotiopsis sp., isolated from the leaves of the Chinese mangrove Rhizophora mucronata, yielded 11 new compounds including cytosporones J-N (1-3, 5-6), five new coumarins pestalasins A-E (8-12), and a new alkaloid named pestalotiopsoid A (14), along with the known compounds cytosporone C (4), dothiorelone B (7), and 3-hydroxymethyl-6,8-dimethoxycoumarin (13). The structures of the new compounds were unambiguously elucidated on the basis of extensive spectroscopic data analysis.

Spectrometry Mass Electrospray IonizationMagnetic Resonance SpectroscopyClinical BiochemistryPharmaceutical ScienceBiochemistryEndophyteCell Linechemistry.chemical_compoundAlkaloidsAscomycotaCoumarinsDrug DiscoveryBotanyAnimalsHumansPestalotiopsisMolecular BiologyRhizophora mucronatabiologyAlkaloidOrganic ChemistryRhizophoraceaePhenolic acidFungi imperfectibiology.organism_classificationchemistryRhizophoraceaeMolecular MedicineSpectrophotometry UltravioletMangroveBioorganic &amp; Medicinal Chemistry
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