Search results for "transitional"
showing 10 items of 125 documents
Results of a Phase I-II Pilot Study with Intravescical Gemcitabine in Superficial Bladder Cancer (Ta-T1)
2005
To study the ablative activity of intravescical gemcitabine against superficial transitional cell carcinoma of the bladder at different doses and concentrations. Methods Twenty-seven patients were treated with intravescical gemcitabine after transurethral resection, during which one to three papillary marker lesions were left unresected. Starting 14 days after transurethral resection, six gemcitabine instillations were given at weekly intervals. Gemcitabine, diluted in 50 mL of saline solution and maintained for 2 hr, was given at a dose of 500, 1000 and 2000 mg in groups of nine patients each. A complete response (CR) was defined as negative cutologycystoscopy and biopsy findings. Results…
Adjuvant Intravesical Chemotherapy in Patients with Primary T1 G3 Transitional Cell Carcinoma of the Bladder
1993
The Authors present their experience with TUR plus adjuvant intravesical chemotherapy in 50 patients affected by primary T1 G3 bladder tumours without previous or concomitant carcinoma in situ. At a mean follow-up of 36 months, 84% of the patients are alive and tumour-free. Cystectomy was performed in three patients due to locally invasive disease. Five patients (10%) died of bladder cancer.
Möglichkeiten und Grenzen der Spiral-CT bei der Untersuchung von Nierenbeckenkarzinomen
1994
PURPOSE To assess the value of spiral CT in comparison to conventional CT in the staging of renal pelvic carcinoma. PATIENTS AND METHODS 35 patients with renal pelvic carcinoma underwent preoperative CT; conventional technique (n = 21) and spiral CT (n = 14) with the reconstruction of thin sections were compared. RESULTS Non-invasive or minimal invasive tumours (TA, T1, T2) could not be differentiated with either technique. Small, flat tumours (TA) or multicentric tumours may be missed, even if spiral scanning is applied. The separation of local tumour growth from infiltration is significantly improved by spiral CT (12 of 12 patients instead of 18 out of 21 patients with the conventional te…
Transitional cell carcinoma of endometrium: a case report of rare pure form
2018
Transitional cell carcinoma is a very rare histological subtype of endometrial cancer, with only 18 cases described in literature. Ovary represents the most common site where it accounts for 2% of all ovarian cancers. Due to the rarity of this disease, current management is controversial and includes various approaches, mostly described in the adjuvant setting, both radiotherapy and chemotherapy alone or in combination. Here, we report a case of a 65-year-old patient who underwent adjuvant vaginal brachytherapy for an endometrial transitional cell carcinoma. The patient was treated with radical total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH-BSO), without lymph-node sa…
Urethral recurrence of transitional cell carcinoma in a female patient after cystectomy and orthotopic ileal neobladder.
2000
A 63-year-old woman presented elsewhere with a unifocal pT1, G3 transitional cell carcinoma at the bladder base in 1995. She underwent urethral sparing cystectomy and ileal neobladder. Intraoperative frozen section from the proximal urethra did not demonstrate tumor involvement. Final histological examination revealed pT1, pN2, G3 transitional cell carcinoma. Adjuvant chemotherapy was not given. In 1998 the patient had symptoms of obstructive voiding due to a 3 3 3 cm. solid mass at the neobladder-urethra anastomosis (see figure). After 6 cycles of methotrexate, vinblastine, doxorubicin and cisplatin and a transient tumor size reduction, the patient was referred to us for local tumor progre…
An Anti-Ubiquitin Antibody Response in Transitional Cell Carcinoma of the Urinary Bladder
2015
BackgroundTo use combinatorial epitope mapping ("fingerprinting") of the antibody response to identify targets of the humoral immune response in patients with transitional cell carcinoma (TCC) of the bladder.MethodsA combinatorial random peptide library was screened on the circulating pool of immunoglobulins purified from an index patient with a high risk TCC (pTa high grade plus carcinoma in situ) to identify corresponding target antigens. A patient cohort was investigated for antibody titers against ubiquitin.ResultsWe selected, isolated, and validated an immunogenic peptide motif from ubiquitin as a dominant epitope of the humoral response. Patients with TCC had significantly higher anti…
Identity and Cultural Transition : Lessons to Learn from a Negative Case Analysis
2020
In this paper, we present a single case study of identity crisis that unfolded in the cultural transition context. Our participant was ‘Jenni’ – a 26 years old female basketball player with the double (Scandinavian and African American) ethnic identity. In a series of life story interviews, she shared her story of migrating to the USA at the age of 16 for sport and study. Jenni’s transition narrative was extracted and analyzed using several complementary theoretical frameworks, including the intersectionality perspective on identity. The analysis of the transition narrative revealed that in spite of the pre-transition high expectations about the transition success, Jenni experienced a crisi…
Reconceptualising the Role of Talk in CLIL
2011
This theoretical paper offers a reconceptualisation of talk in CLIL based on sociocultural and dialogic theories of education. Building on these educational theories and the experiences of an on-going CLIL project, this paper presents a pedagogical model for the navigation of the ‘talkscape’ of the CLIL classroom. This model comprises a total of seven talk-types: organisational, social, critical, expert, exploratory, meta and pedagogic. In addition to these talk-types, the paper introduces the notion of a ‘transitional dynamic’. This notion aims to capture the transition from first language to foreign language use in CLIL both within the context of individual courses and across a broader CL…
Konstytucyjna zasada równości w kontekście przepisów abolicyjnych w ustawie Polski Ład
2022
Artykuł został poświęcony instytucji przejściowego ryczałtu od dochodów wprowadzonej ustawą Polski Ład. Jak wykazano, w istocie spełnia ona kryteria abolicji podatkowej i jednocześnie budzi poważne wątpliwości co do zgodności z konstytucyjnymi zasadami równości (art. 32 Konstytucji RP) i powszechności opodatkowania (art. 84 Konstytucji RP). W publikacji przedstawiono instytucję abolicji podatkowej, jej istotę i rys historyczny oraz normatywną konstrukcję przejściowego ryczałtu od dochodów. Analizie poddano także zgodność przepisów normujących instytucję przejściowego ryczałtu od dochodów ze wskazanymi przepisami ustawy zasadniczej
Study of the Stability of Citrate Capped AgNPs in Several Environmental Water Matrices by Asymmetrical Flow Field Flow Fractionation
2021
Asymmetrical flow field-flow fractionation (AF4) coupled to UV-Vis and dynamic light scattering (DLS) detectors in series, was tested for stability studies of dispersions of citrate-capped silver nanoparticles (AgNPs) in several water matrices. The main goal is to provide knowledge to understand their possible behavior in the environment for short times since mixturing (up to 180 min). Ultrapure (UPW), bottled (BW1, BW2), tap (TW), transitional (TrW) and sea water (SW) matrices were assayed. Observations were compatible with the aggregation of AgNPs, a change in the plasmon band and a size growth with time were done. Fractograms showed different evolution fingerprints in the function of the…