Search results for "trap"

showing 10 items of 2144 documents

Separating the Mechanism-Based and Off-Target Actions of Cholesteryl Ester Transfer Protein Inhibitors With CETP Gene Polymorphisms

2010

Background— Cholesteryl ester transfer protein (CETP) inhibitors raise high-density lipoprotein (HDL) cholesterol, but torcetrapib, the first-in-class inhibitor tested in a large outcome trial, caused an unexpected blood pressure elevation and increased cardiovascular events. Whether the hypertensive effect resulted from CETP inhibition or an off-target action of torcetrapib has been debated. We hypothesized that common single-nucleotide polymorphisms in the CETP gene could help distinguish mechanism-based from off-target actions of CETP inhibitors to inform on the validity of CETP as a therapeutic target. Methods and Results— We compared the effect of CETP single-nucleotide polymorphisms …

high-density lipoproteinsEpidemiologyBLOOD-PRESSUREPharmacologyDISEASEchemistry.chemical_compoundDOUBLE-BLINDHigh-density lipoprotein:CIENCIAS MÉDICAS ::Medicina interna [UNESCO]Polymorphism (computer science)Physiology (medical)Cholesterylester transfer proteinGeneticsMedicinegeneticsHigh-density lipoproteinsGENOME-WIDE ASSOCIATIONUNESCO::CIENCIAS MÉDICAS ::Medicina internaPharmacologyHDL CHOLESTEROLbiologybusiness.industryCholesterolTorcetrapib:CIENCIAS MÉDICAS [UNESCO]Genetics ; Pharmacology ; Epidemiology ; High-density lipoproteinsDose–response relationshipBlood pressurechemistryATHEROSCLEROSISUNESCO::CIENCIAS MÉDICASbiology.proteinMENDELIAN RANDOMIZATIONepidemiology; genetics; high-density lipoproteins; pharmacologylipids (amino acids peptides and proteins)epidemiologyTORCETRAPIBpharmacologyCardiology and Cardiovascular MedicinebusinessHIGH-DENSITY-LIPOPROTEINLIPID-LEVELSLipoproteinCirculation
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Supplementing air with CO2 stripped from recirculating aquaculture improves growth of two green microalgae in aquaculture wastewater

2023

To improve sustainability and to implement the principles of circular economy in aquaculture, we tested the possibility to boost the capture of nitrate by two green microalgal species from recirculating aquaculture system's (RAS) wastewater by supplementing air with carbon dioxide stripped from a RAS. Carbon dioxide addition increased cell densities of Monoraphidium griffithii and Haematococcus pluvialis in photobioreactors during 9-day growing periods. However, growth rates and nitrate uptake rates were only improved for M. griffithii. Addition of CO2 decreased pH of the medium with M. griffithii which likely also affected positively on algal growth and nutrient uptake. These laboratory sc…

hiilidioksidiphotobioreactorcircular economydissolved nutrientsnutrient trappingkiertotalouscarbon dioxidejätevesinitraatitAquatic ScienceAquaculture
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Reconstrucció del paisatge rural i urbà d'Almenara i La Llosa entre els segle XIII al XVI

2023

La tesi titulada «Reconstrucció del paisatge rural i urbà d'Almenara i La Llosa entre els segles XIII-XVI», aprofundeix en l'evolució del paisatge cultural d'ambdós municipis i l'estudi de la seua població. Amb la finalitat de valorar els béns culturals municipals d'aquest període i destacar-ne la rellevància i les funcions en el passat. Cosa que possibilita una millor acceptació en el manteniment i en el respecte d'aquests béns en la societat actual. El paisatge constitueix una realitat dinàmica, ja que és resultat de processos ambientals, socials i culturals que s'han succeït al llarg del temps en el territori. Aquests processos estan marcats per les maneres de vida, les polítiques, les a…

història de l'artcomtat d'almenarademografiaurbanismesistema hidràulicsegle xvgvsigalmenarapaisatge culturalmolinsgermaniesgeografiaprovíncia de castellóbarri marineragriculturarecomptesalqueries musulmanespròixidageorreferènciaramaderiaUNESCO::HISTORIAsegle xvibaronia de la llosala plana baixahistòriamusulmansgovernsucrela llosapaisatge ruralfirasegle xivsegle xviiport o carregador d'almenarafont de quartbatalla d'almenarapunt del cidfont redonafont de la llosarafalscastell d'almenararuscos de meltorre de costacensosbassa de regtrapigsegle xiiiséquia majorusos comunalsrevoltes múdejarsenginypatrimoni culturalpaisatge urbàmuralles d'almenaraempriusrapitacomunitat valencianavilallanamoreresmoriscos
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Penning-trap-assisted decay spectroscopy studies of neutron-rich nuclei in the A = 110 region

2011

hiukkasloukutJYFLTRAP-ioniloukkuspectroscopyisotoopitionitPenning trapPenningin loukkuspektroskopiaioniloukutneutronirikkaat ytimetneutron-rich fission productsydinfysiikkaisotopes
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Intrapartum analgesia as condition of human satisfaction at hospital

2013

The study investigates parturients’ satisfaction with intrapartum analgesia. It aims to assess their opinions about hospital and health staff involved in delivery, besides investigating emotional control, locus control and bond between mothers and their newborn infants. A multidimensional approach has been used to investigate the variable of woman as a person, the variable of context and the variable of bond with the newborn infant. The study was conducted according to a quasi-experimental design, with a control group. The study was performed within the Analgesia and Intensive Care Operational Unit of the Maternal-Infant Department of the P. Giaccone University General Hospital of Palermo. …

human satisfactiondepressionintrapartum analgesialocus of controlanxietypregnant women
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Role of elastic and electronic interactions in trapping of hydrogen by impurities in transition metals

1985

The interplay between the lattice distortion and the electronic contributions to the trapping of migrating hydrogen isotopes by substitutional impurities is investigated. We use a comprehensive calculational scheme incorporating (i) the effective-medium theory for the electronic interaction, (ii) the lattice Green’s function for elastic coupling, and (iii) the hydrogen quantum motion. The calculations for Ti and Cr impurities in V host show that lattice strain effects dominate. Cr, which otherwise provides an electronic trap site, does not induce trapping when elastic effects are incorporated. The situation in the case of Ti is just the reverse. We find no isotope dependence of the binding …

hydrogen isotopesMaterials scienceTransition metalHydrogenchemistryImpurityChemical physicsPhysicschemistry.chemical_elementTrappingPhysics::Atomic PhysicsAtomic physicstransition metals
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Plasma leptin or VEGF are little affected by maximal exercise at high altitude (5050 m)

2010

hypoxemiahypoxia; physical activity; extrapulmonary impacthypoxiaphysical activitySettore MED/10 - Malattie Dell'Apparato Respiratorioextrapulmonary impacthypobaric hypoxiaSettore BIO/09 - Fisiologiaincremental exercise
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Colon Bioaccessibility under In Vitro Gastrointestinal Digestion of Different Coffee Brews Chemically Profiled through UHPLC-Q-Orbitrap HRMS

2021

Coffee represents one of the most traditionally consumed beverages worldwide, containing a broad range of human health&ndash

in vitro gastrointestinal digestionHealth (social science)Antioxidant030309 nutrition & dieteticsmedicine.medical_treatmentcoffeePlant ScienceOrbitraplcsh:Chemical technologyHealth Professions (miscellaneous)MicrobiologyArticleGastrointestinal digestionlaw.invention03 medical and health scienceschemistry.chemical_compound0302 clinical medicinelawchlorogenic acidsmedicinelcsh:TP1-1185Food sciencepolyphenols0303 health sciencesChemistryChlorogenic acidIn vitrobioaccessibilityCaffeoylquinic acidAntioxidant capacityPolyphenol030220 oncology & carcinogenesisCaffeineFood ScienceFoods
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Initialization of the JYFLTRAP system

2013

The IGISOL facility has been moved into a new location at the acceleration laboratory of the University of Jyväskylä. The superconducting magnet that is part of the JYFLTRAP system has been re-energized. In this thesis a commissioning of the Penning trap apparatus JYFLTRAP is described. This involves a precise alignment of the structure of the trap along field lines of strong solenoid field. The alignment was completed successfully with a special alignment device. In addition, some improvements were done for the Penning traps and transfer line from RFQ cooler, and a buncher to the injection of Penning traps was built during this project. Jyväskylän yliopiston IGISOL-ryhmän laboratorio on mu…

initializationJYFLTRAPalignmentlaboratoriotkäyttöönotto
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Characteristics of Intrapreneurs in Scale-Intensive Service Firms

2014

This empirical paper explores the work of employees in charge of service innovation when firms develop and launch new scale-intensive services by addressing two research questions: i) How do employees responsible for service innovation work? and ii) what are the related managerial implications when developing and launching new scale-intensive services? To this end, 21 qualitative, in-depth interviews were conducted with employees in five large scale-intensive service firms. The findings suggest that the involvement of internal professionals is an asset when new scale-intensive services are developed, and that internal professionals act as intrapreneurs when they are involved in the developm…

innowacje dotyczące usługService (business)lcsh:Management. Industrial managementscale-intensive servicesComputingMilieux_THECOMPUTINGPROFESSIONComputer scienceDownloadintrapreneurshipzarządzanie innowacjamilcsh:BusinessPermissionservice innovationWorld Wide Webprzedsiębiorczość wewnętrznalcsh:HD28-70Management of Technology and InnovationTourism Leisure and Hospitality ManagementScale (social sciences)Institution (computer science)usługi o intensywnej skaliBusiness and International Managementlcsh:HF5001-6182Open access journalinnovation management
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