Search results for "triazol"
showing 10 items of 598 documents
Inhibitoren der Korrosion 30 (1,2) - Vergleichende Studien über das Verhalten bekannter und bisher unbekannter Inhibitoren der Korrosion des Kupfers …
1985
Folgende Verbindungen wurden auf ihre Fahigkeit zur Inhibierung der Korrosion von Kupferproben unter Standardbedingungen uberpruft: Benzotriazol (BTA), 5-Aminotetrazol-monohydrat (5-AT), 2,5-Diphenyl-3-(m-chlorphenyl)-tetrazolium-nitrat (Tetrazin-B), α- und β-Naphthylamin, Phenylthioharnstoff, Xanthanwasserstoff, 2-Mercaptothiazolin (2-MT) und Kupferron. Folgende Messungen wurden durchgefuhrt: Bestimmung der Geschwindigkeit der Sauerstoffaufnahme im Schuttelversuch und pH-statische Verfolgung des Korrosionsverlaufs in Abhangigkeit (a) von der Konzentration des Inhibitors, (b) dem Verteilungszustand der Kupferprobe (Korn, Staub, Blech), (c) der Anwesenheit von Cu2+-Ionen und (d) dem pH-Wert.…
1-Benzyl-1H-benzotriazole
2012
In the title compound, C13H11N3, the benzotriazole ring system is essentially planar, with a maximum deviation of 0.0173 (18) Å, and forms a dihedral angle of 75.08 (8)Å with the phenyl ring. In the crystal, pairs of weak C—H...N hydrogen bonds form inversion dimers. In addition, there are weak C—H...π(arene) interactions and weak π–π stacking interactions, with a centroid–centroid distance of 3.673 (11) Å.
1-Benzyloxy-1H-benzotriazole
2012
In the title compound, C13H11N3O, the dihedral angle between the benzotriazole ring system [maximum deviation = 0.027 (16) Å] and the benzene ring is 10.28 (9)°. The C—C—O—N bond adopts an anti conformation [torsion angle = −177.11 (16)°]. In the crystal, the molecules interact via weak C—H...π interactions and aromatic π–π stacking [centroid-to-centroid distance = 3.731 (12) Å].
1-Benzyl-1H-benzotriazole 3-oxide monohydrate
2012
In the title hydrate, C13H11N3O·H2O, the benzotriazole ring system is planar (r.m.s. deviation = 0.007 Å) and is almost orthogonal to the phenyl ring to which it is linked by a methylene group, forming a dihedral angle of 81.87 (15)°. In the crystal, molecules are linked into chains along [001] by O—H...O hydrogen bonds. The chains are consolidated into a three-dimensional architecture by C—H...O, C—H...π and π–π [centroid–centroid distance between the five- and six-membered rings of the benzotriazole ring system = 3.595 (3) Å] interactions.
1-Mesitylmethyl-1Hbenzotriazole 3-oxide.
2010
In the title compound, C16H17N3O, the benzotriazole ring forms a dihedral angle of 77.25 (6)° with the phenyl ring. The benzotriazole ring is essentially planar with a maximum deviation of 0.012 (19) Å. Weak intermolecular C—H...O hydrogen bonds form R22(10) motifs. The crystal packing is consolidated by π—π interactions with centroid–centroid distances of 3.5994 (12) Å together with very weak C—H...π interactions.
1-Benzyl-1H-benzotriazole 3-oxide-1-hy-droxy-1H-benzotriazole (1/1).
2012
In the title compound, C6H5N3O·C13H11N3O, the benzotriazole ring system in the 1-benzyl-1H-benzotriazole 3-oxide (A) molecule is close to being planar (r.m.s. deviation = 0.011 Å); its mean plane forms a dihedral angle of 67.56 (7)° with that of the attached phenyl ring. The benzotriazole ring system in the 1-hydroxybenzotriazole (B) molecule is also close to being planar (r.m.s. deviation = 0.010 Å). In the crystal, weak C—H...O and C—H...π interactions are present. TheAandBmolecules are linked by an O—H...N hydrogen bond.
Synthesis and photovoltaic performance of the porphyrin based sensitizers with 2H-[1,2,3]triazolo[4,5-c]pyridine and benzotriazole as auxiliary accep…
2017
Abstract Two novel zinc porphyrin dyes containing either benzotriazole or 2 H -[1,2,3]triazolo[4,5- c ]pyridine as auxiliary acceptors, respectively, were synthesized for dye-sensitized solar cells. These two auxiliary acceptors were firstly applied into porphyrin based dyes. The photophysical and electrochemical properties of the dyes were investigated. These two dyes show the whole visible light absorption when they are adsorbed on the TiO 2 film, which means that they are promising sensitizers for dye-sensitized solar cells. The absorption intensity of the triazolopyridine containing dye is higher than that of the benzotriazole containing dye, resulting in a better light harvesting. Thus…
1,5-Disubstituted 1,2,3-Triazoles as Amide Bond Isosteres Yield Novel Tumor-Targeting Minigastrin Analogs.
2021
[Image: see text] 1,5-Disubstituted 1,2,3-triazoles (1,5-Tz) are considered bioisosteres of cis-amide bonds. However, their use for enhancing the pharmacological properties of peptides or proteins is not yet well established. Aiming to illustrate their utility, we chose the peptide conjugate [Nle(15)]MG11 (DOTA-dGlu-Ala-Tyr-Gly-Trp-Nle-Asp-Phe-NH(2)) as a model compound since it is known that the cholecystokinin-2 receptor (CCK2R) is able to accommodate turn conformations. Analogs of [Nle(15)]MG11 incorporating 1,5-Tz in the backbone were synthesized and radiolabeled with lutetium-177, and their pharmacological properties (cell internalization, receptor binding affinity and specificity, pla…
Role of calcium in E-selectin induced phenotype of T84 colon carcinoma cells
2003
The adhesion of cancer cells to the endothelium during the metastatic process involves the interaction of specific cell-cell adhesion receptors on the cell surface. E-selectin on endothelial cells and sialyl Lewis X carbohydrate component on tumor cells are mainly implicated in the adhesion of colon carcinoma cells to the endothelium of target organ. In this paper we show that binding of E-selectin to T84 colon tumor cells causes approximately a twofold increase in intracellular calcium concentration. In particular, using two inhibitors of receptor operated calcium channels, CAI and SK&F 96365, we present evidences that the augmentation in cytoplasmic calcium originates from ionic influx fr…
Efficacy and safety of canagliflozin over 52 weeks in patients with type 2 diabetes on background metformin and pioglitazone.
2014
Aim The efficacy and safety of canagliflozin, a sodium glucose co-transporter 2 inhibitor, was evaluated in patients with type 2 diabetes mellitus (T2DM) inadequately controlled with metformin and pioglitazone. Methods In this randomized, double-blind, phase 3 study, patients (N = 342) received canagliflozin 100 or 300 mg during a 26-week, placebo-controlled, core period and a 26-week, active-controlled extension in which placebo-treated patients were switched to sitagliptin 100 mg. Efficacy comparisons for canagliflozin versus placebo at week 26 are reported, with no comparisons versus sitagliptin at week 52 (sitagliptin used to maintain double-blind and control for safety). Safety data ar…