Search results for "trigeminal"

showing 3 items of 93 documents

A “Painful Tic Convulsif” (Trigeminal Neuralgia And Ipsilateral Facial Spasm) Due To Double Neuro-Vascular Impingement: A Case Report.

2011

painful tic convulsif trigeminal neuralgia facial spasm neurovascular impingement
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A Novel Pathophysiological Mechanism Contributing to Trigeminal Neuralgia

2016

Trigeminal neuralgia (TN) is a form of neuropathic pain that affects the fifth cranial nerve, the most widely distributed nerve in the head. Although TN has been associated with a variety of pathological conditions, neurovascular compression on the trigeminal nerve, as it exits the brain stem, is the most frequent reported cause. This compression provides a progressive demyelination of the nerve and a subsequent aberrant neural transmission. Although several studies have clarified some physiopathological mechanisms underlying TN, the molecular basis remains vague. Very recently the substitution of methionine 136 by valine (MET126Val) in sodium channel Nav1.6 in a case study of typical TN ha…

trigeminal ganglionlcsh:Biochemistry03 medical and health sciencesTrigeminal ganglion0302 clinical medicineaction potentialTrigeminal neuralgianeurovascualr compressionGeneticsmedicinelcsh:QD415-436Molecular BiologyPathologicalTrigeminal neuralgia; action potential; molecular mechanism; neurovascualr compression; trigeminal ganglionGenetics (clinical)Trigeminal nervebusiness.industrySodium channellcsh:RM1-950medicine.diseasePathophysiologylcsh:Therapeutics. Pharmacology030220 oncology & carcinogenesisAnesthesiaNeuropathic painMolecular MedicineBrainstemmolecular mechanismbusinessNeuroscience030217 neurology & neurosurgeryTrigeminal neuralgiaResearch Article
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Enhancement by TNF-alpha of reactivation and replication of latent herpes simplex virus from trigeminal ganglia of mice.

1995

The influence of tumor-necrosis-factor-alpha (TNF-alpha), granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukine-1 (IL-1) and IL-3 on the in vitro reactivation frequency and replication rate of trigeminal ganglia of mice latently infected with herpes simplex virus (HSV) strain KOS was studied. It could be demonstrated that TNF-alpha and possibility GM-CSF, but not IL-1 and IL-3, enhanced the reactivation frequency and replication of HSV. Interferon alpha/beta (IFN alpha/beta) prevented reactivation and replication.

virusesmedicine.medical_treatmentHerpesvirus 1 HumanBiologymedicine.disease_causeVirus ReplicationVirusHerpesviridaeMiceInterferonVirologyAlphaherpesvirinaeChlorocebus aethiopsmedicineAnimalsHumansVero CellsMice Inbred BALB CTumor Necrosis Factor-alphaGranulocyte-Macrophage Colony-Stimulating FactorInterferon-alphaGeneral MedicineInterferon-betabiology.organism_classificationVirologyIn vitroVirus LatencyCytokineHerpes simplex virusViral replicationTrigeminal GanglionInterleukin-3Virus Activationmedicine.drugInterleukin-1Archives of virology
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