Search results for "twist"

showing 10 items of 82 documents

TWIST and p-Akt immunoexpression in normal oral epithelium, oral dysplasia and in oral squamous cell carcinoma

2010

Objectives: The aim of this study was to evaluate the immunoexpression of TWIST and p-Akt proteins in oral leukoplakia (OL) and oral squamous cell carcinoma (OSCC), correlating their expressions with the histological features of the lesions. Study design: Immunohistochemical studies were carried out on 10 normal oral epithelium, 30 OL and 20 OSCC formalin-fixed, paraffin-embedded tissue samples. Immunoperoxidase reactions for TWIST and p-Akt proteins were applied on the specimens and the positivity of the reactions was calculated for 1000 epithelial cells. Results: Kruskal-Wallis and Dunn’s post tests revealed a significant difference in TWIST and p-Akt immunoexpression among normal oral mu…

MalePathologymedicine.medical_specialtyEpitheliumTwist transcription factormedicineHumansGeneral DentistryMouth neoplasmOral DysplasiaOral Medicine and PathologyImmunoperoxidasebusiness.industryTwist-Related Protein 1CancerMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseEpitheliumstomatognathic diseasesmedicine.anatomical_structureOtorhinolaryngologyDysplasiaUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellImmunohistochemistryFemaleMouth NeoplasmsResearch-ArticleSurgeryLeukoplakia OralbusinessProto-Oncogene Proteins c-aktMedicina Oral Patología Oral y Cirugia Bucal
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On the blue phase structure of hydrogen-bonded liquid crystals via 19F NMR

2018

Abstract 19 F NMR spectra are simulated for blue phase I of FPHG( St 1.5 ∗ Ap 1.5 ) based on a model of a double-twisted substructure inside cylinders that form a body-centred cubic lattice. A kinetic matrix is included to describe jump processes over quarter pitch lengths. Though the lines in the NMR spectra are broad and featureless, changes in the widths and positions with temperature are well described by the blue phase model structure. The spectra in the chiral nematic N∗ phase are also simulated. Dynamics in the BP I are found to be slower than in the N∗ phase.

Materials scienceHydrogenSpectral simulationChemieGeneral Physics and Astronomychemistry.chemical_elementBlue phase IDouble-twisted substructure02 engineering and technologyFluorine-19 NMR010402 general chemistryKinetic energy01 natural sciencesMolecular physicsSpectral lineDiffusion rateLiquid crystalLattice (order)Physical and Theoretical Chemistry021001 nanoscience & nanotechnologyFluorine NMR0104 chemical sciencesNMR spectra databasechemistrySubstructureSettore CHIM/07 - Fondamenti Chimici Delle Tecnologie0210 nano-technologyChiral nematic
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Micro-photoluminescence of Carbon Dots Deposited on Twisted Double-Layer Graphene Grown by Chemical Vapor Deposition

2021

Carbon-based nanomaterials, such as carbon dots (CDs) and graphene (Gr), feature outstanding optical and electronic properties. Hence, their integration in optoelectronic and photonic devices is easier thanks to their low dimensionality and offers the possibility to reach high-quality performances. In this context, the combination of CDs and Gr into new nanocomposite materials CDs/Gr can further improve their optoelectronic properties and eventually create new ones, paving the way for the development of advanced carbon nanotechnology. In this work, we have thoroughly investigated the structural and emission properties of CDs deposited on single-layer and bilayer graphene lying on a SiO2/Si …

Materials sciencechemistry.chemical_element02 engineering and technologyChemical vapor deposition010402 general chemistry01 natural sciencesNanomaterialslaw.inventionsymbols.namesakemicro-photoluminescencelawcarbon dotsGeneral Materials ScienceNanocompositebusiness.industryGrapheneBilayer021001 nanoscience & nanotechnology0104 chemical scienceschemistryRaman spectroscopysymbolsOptoelectronicstwisted bilayer grapheneAFM0210 nano-technologybusinessRaman spectroscopyBilayer grapheneCarbon
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On the existence of invariant curves of twist mappings of an annulus

1983

Mathematical analysisHolomorphic functionInvariant (mathematics)TwistImplicit function theoremIteration processRotation numberMathematics
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CVBEM solution for De Saint-Venant orthotropic beams under coupled bending and torsion

2014

The aim of this paper is to provide a solution for the coupled flexure–torsion De Saint Venant problem for orthotropic beams taking full advantage of the complex variable boundary element method (CVBEM) properly extended using a complex potential function whose real and imaginary parts are related to the shear stress components, the orthotropic ratio and the Poisson coefficients. The proposed method returns the complete stress field and the unitary twist rotation of the cross section at once by performing only line integrals. Numerical applications have been reported to show the validity and the efficiency of the proposed modified CVBEM to handle shear stress problems in the presence of ort…

Mechanical EngineeringMathematical analysisComputational MechanicsLine integralCVBEMTorsion (mechanics)GeometryPhysics::Classical PhysicsOrthotropic materialComputer Science::Numerical AnalysisStress fieldSolid mechanicsShear stressorthotropic beamsTwistSettore ICAR/08 - Scienza Delle CostruzioniBoundary element methodMathematicsActa Mechanica
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CVBEM application to a novel potential function providing stress field and twist rotation at once

2013

AbstractIn this paper, complex variable boundary element method (CVBEM) is used for the solution of de Saint-Venant’s torsion problem in homogenous isotropic elastic beams with a generic cross section, considering a complex potential function related to the stress field. Generally, CVBEM, when used for torsion problems, leads to evaluation of the stress field divided by the twist rotation. The latter has been evaluated by performing a domain integral. In this paper, taking advantage of the aforementioned potential function, it is possible, by applying CVBEM, to evaluate the complete stress distribution and the twist rotation of the cross section and the torsional stiffness factor, performin…

Mechanical EngineeringMathematical analysisIsotropyLine integralA domainTorsion (mechanics)CVBEMPotential theoryStress fieldClassical mechanicsMechanics of MaterialsTwistBoundary element methodMathematics
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Recurrent Mutations in the Basic Domain of TWIST2 Cause Ablepharon Macrostomia and Barber-Say Syndromes

2015

Contains fulltext : 153827.pdf (Publisher’s version ) (Open Access) Ablepharon macrostomia syndrome (AMS) and Barber-Say syndrome (BSS) are rare congenital ectodermal dysplasias characterized by similar clinical features. To establish the genetic basis of AMS and BSS, we performed extensive clinical phenotyping, whole exome and candidate gene sequencing, and functional validations. We identified a recurrent de novo mutation in TWIST2 in seven independent AMS-affected families, as well as another recurrent de novo mutation affecting the same amino acid in ten independent BSS-affected families. Moreover, a genotype-phenotype correlation was observed, because the two syndromes differed based s…

Models MolecularCandidate geneHirsutismProtein ConformationHeLa Cellmedicine.disease_causeTranscriptomeTwist transcription factorModelsGenetics(clinical)ExomeEye AbnormalitiesNon-U.S. Gov'tExomeGenetics (clinical)ZebrafishGeneticsMutationMicroscopyMacrostomiaSetleis syndromeHypertelorismResearch Support Non-U.S. Gov'tHypertrichosiEyelid DiseaseGENÉTICAPhenotypeEyelid DiseasesAbnormalitiesMultipleSequence AnalysisHumanChromatin ImmunoprecipitationMolecular Sequence DataMutation MissenseHypertrichosisAbnormalities; Multiple; Amino Acid Sequence; Animals; Base Sequence; Chromatin Immunoprecipitation; Exome; Eye Abnormalities; Eyelid Diseases; HeLa Cells; Hirsutism; Humans; Hypertelorism; Hypertrichosis; Macrostomia; Microscopy; Electron; Molecular Sequence Data; Mutation; Missense; Protein Conformation; Repressor Proteins; Sequence Analysis; DNA; Skin Abnormalities; Twist Transcription Factor; Zebrafish; Models; Molecular; Phenotype; Genetics; Genetics (clinical)Other Research Radboud Institute for Molecular Life Sciences [Radboudumc 0]BiologyResearch SupportElectronArticleFrameshift mutationGeneticAblepharon macrostomia syndromeSkin AbnormalitieGeneticsmedicineJournal ArticleAnimalsHumansAbnormalities MultipleAmino Acid SequenceNeurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7]Base SequenceAnimalTwist-Related Protein 1MolecularSequence Analysis DNADNARepressor Proteinmedicine.diseaseRepressor ProteinsTwist Transcription FactorEye AbnormalitieMicroscopy ElectronMutationSkin Abnormalitiessense organsMissenseNanomedicine Radboud Institute for Molecular Life Sciences [Radboudumc 19]HeLa CellsAmerican journal of human genetics
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Hilbert modularity of some double octic Calabi--Yau threefolds

2018

We exhibit three double octic Calabi--Yau threefolds over the certain quadratic fields and prove their modularity. The non-rigid threefold has two conjugate Hilbert modular forms of weight [4,2] and [2,4] attached while the two rigid threefolds correspond to a Hilbert modular form of weight [4,4] and to the twist of the restriction of a classical modular form of weight 4.

Modularity (networks)Pure mathematicsAlgebra and Number TheoryMathematics - Number Theory010102 general mathematicsModular formField (mathematics)010103 numerical & computational mathematics01 natural sciencesMathematics - Algebraic GeometryQuadratic equationMathematics::Algebraic GeometryFOS: MathematicsCalabi–Yau manifoldNumber Theory (math.NT)0101 mathematicsTwistHilbert modular formAlgebraic Geometry (math.AG)Mathematics
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Specific expression patterns of epithelial to mesenchymal transition factors in gestational molar disease.

2015

Introduction The epithelial to mesenchymal transition, a well-known and re-emerging model in pathology, has not been completely investigated in the field of gestational pathology. This study aims at improving the comprehension of this process in molar disease, even looking for new possible immunohistochemical markers. Materials and methods We have analysed the immunohistochemical expression of Twist1 and Snai2, two of the most important transcription factors involved in epithelial to mesenchymal transition, in formalin-fixed paraffin-embedded samples of 23 spontaneous abortive pregnancies, 22 molar pregnancies (10 partial and 12 complete) and 7 term placentas. Results Twist1 and Snai2 were …

MolarPathologymedicine.medical_specialtyStromal cellEpithelial-Mesenchymal TransitionBiologyPregnancymedicineHumansEpithelial–mesenchymal transitionTwistClaudinComplete mole; EMT; Molar disease; Snai2; Twist; Twist1; Obstetrics and Gynecology; Reproductive Medicine; Developmental BiologyCadherinTwist-Related Protein 1EMTObstetrics and GynecologyTrophoblastNuclear ProteinsHydatidiform MoleImmunohistochemistryComplete mole; EMT; Molar disease; Snai2; Twist; Twist1Complete moleSNAI2Molar diseasemedicine.anatomical_structureReproductive MedicineSnai2Case-Control StudiesImmunohistochemistryFemaleSnail Family Transcription FactorsBiomarkersTwist1Developmental BiologyTranscription FactorsPlacenta
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The importance of kinematic twists and genuine saturation effects in dijet production at the Electron-Ion Collider

2021

We compute the differential yield for quark anti-quark dijet production in high-energy electron-proton and electron-nucleus collisions at small $x$ as a function of the relative momentum $\boldsymbol{P}_\perp$ and momentum imbalance $\boldsymbol{k}_\perp$ of the dijet system for different photon virtualities $Q^2$, and study the elliptic and quadrangular anisotropies in the relative angle between $\boldsymbol{P}_\perp$ and $\boldsymbol{k}_\perp$. We review and extend the analysis in [1], which compared the results of the Color Glass Condensate (CGC) with those obtained using the transverse momentum dependent (TMD) framework. In particular, we include in our comparison the improved TMD (ITMD…

Nuclear Theoryquark antiquarkQC770-798hiukkasfysiikkaPROTONtransverse momentum dependence01 natural scienceslaw.inventionColor-glass condensateGLUON DISTRIBUTION-FUNCTIONSHigh Energy Physics - Phenomenology (hep-ph)lawEQUATIONSaturation (graph theory)Wave functionPhysicselectron nucleon: colliding beamsQUARK PAIR PRODUCTIONFLUCTUATIONSQCD PhenomenologyQCD phenomenologyHigh Energy Physics - PhenomenologykinematicstwistPhysics::Space PhysicsProduction (computer science)Quarkdijet: productionCOLLISIONSNuclear and High Energy PhysicsParticle physics[PHYS.NUCL]Physics [physics]/Nuclear Theory [nucl-th]FOS: Physical sciencesanisotropy114 Physical sciencesdihadron: angular correlationdeep inelastic scattering (phenomenology)AZIMUTHAL CORRELATIONSMomentumelectron p: scatteringNuclear Theory (nucl-th)Nuclear and particle physics. Atomic energy. Radioactivity0103 physical sciencesWAVE-FUNCTIONS010306 general physicsColliderDeep Inelastic Scattering (Phenomenology)010308 nuclear & particles physicselectron nucleus: scatteringHigh Energy Physics::PhenomenologyEVOLUTIONGluon[PHYS.HPHE]Physics [physics]/High Energy Physics - Phenomenology [hep-ph]gluon: saturationcolor glass condensateHigh Energy Physics::ExperimentkvanttiväridynamiikkaJournal of High Energy Physics
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